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科技导报 |综述文章 2014 , 32 (17) : 71 -75
硼中子俘获治疗中血硼浓度的测量方法
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赵修良, 金晓峰, 程晓龙, 周剑良, 雷龙, 曹舟
作者信息
    南华大学核科学技术学院, 衡阳 421001
通讯作者:
周剑良,教授,研究方向为核技术应用及辐射防护技术,电子信箱:m15211361861@163.com
作者简介:
赵修良,教授,研究方向为核电子学与测控技术,电子信箱:zxl13327341099@163.com
Development of Blood Boron Concentration Measurement in Boron Neutron Capture Therapy
  • ZHAO Xiuliang, JIN Xiaofeng, CHENG Xiaolong, ZHOU Jianliang, LEI Long, CAO Zhou
  • Affiliations
      School of Nuclear Science and Technology, University of South China, Hengyang 421001, China
    出版时间: 2014-06-18 doi: 10.3981/j.issn.1000-7857.2014.17.011
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    介绍了硼中子俘获治疗(BNCT)过程中的血硼浓度测量的概念,分析总结了物理测量法、化学测量法、核测量法这3 种测量血硼浓度方法的不足。其中,着重介绍了基于核测量法的血硼浓度测量技术。血硼浓度的快速精确的测量是硼中子俘获治疗过程中的关键,综述了核测量法——瞬发γ射线中子活化分析(PGNAA)技术的发展及应用;PGNAA装置测量血硼浓度的技术现状;当前核测量方法存在的问题及解决办法。认为未来硼浓度测量技术的发展方向是BNCT治疗肿瘤时四维估算照射剂量技术。
    血硼浓度  /  核测量法  /  硼中子俘获治疗
    This paper introduces the concept of blood born concentration measurement in the process of boron neutron capture therapy (BNCT). The deficiency of the physical, chemical, and nuclear methods for blood boron measurement is analyzed with a focus on the nuclear method. Rapidly and accurately measuring the blood boron concentration is the key in the process of BNCT. The status quo and development of the prompt gamma neutron activation analysis (PGNAA) are discussed. The problems and solutions of existing nuclear measurement methods are summarized. Future techniques for measuring blood boron concentration may be oriented toward fourdimensional estimation of exposure dose in the process of tumor therapy using BNCT.
    blood boron  /  nuclear measurement method  /  boron neutron capture therapy
    赵修良, 金晓峰, 程晓龙, 周剑良, 雷龙, 曹舟. 硼中子俘获治疗中血硼浓度的测量方法. 科技导报, 2014 , 32 (17) : 71 -75 . DOI: 10.3981/j.issn.1000-7857.2014.17.011
    ZHAO Xiuliang, JIN Xiaofeng, CHENG Xiaolong, ZHOU Jianliang, LEI Long, CAO Zhou. Development of Blood Boron Concentration Measurement in Boron Neutron Capture Therapy[J]. Science & Technology Review, 2014 , 32 (17) : 71 -75 . DOI: 10.3981/j.issn.1000-7857.2014.17.011

      国家国防科技工业局军品配套科研项目(JPPT-115-5-882)

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    doi: 10.3981/j.issn.1000-7857.2014.17.011
    • 接收时间:2014-02-18
    • 首发时间:2014-06-20
    • 出版时间:2014-06-18
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    • 收稿日期:2014-02-18
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    周剑良,教授,研究方向为核技术应用及辐射防护技术,电子信箱:m15211361861@163.com
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    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
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