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利用核移植技术建立哺乳类动物模型
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周琪
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    中国科学院动物研究所,北京,100080
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    出版时间: 2004-02-10
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    随着大众对人类健康的日益关注、现代医药事业的不断发展,新药物的研制和试验日益显得重要。但这类与人类自身相关的科学研究如果在人体上进行试验,则风险很大;如果通过实验方法使实验动物产生与人类相似的生理状态,或将外源基因导入实验动物,则能使其稳定地整合,从而表达并产生相应的生理效应,建立能够模拟人类生理或病理状态的动物模型。通过对具有与人类疾病相似的动物模型的研究,可使药物试验等试验工作准确无误,更接近真实,使实验结果具有科学性和重复性,从而促进人类健康事业的发展。
    细胞核移植  /  模式动物  /  动物模型  /  人类健康  /  生物制药
    周琪. 利用核移植技术建立哺乳类动物模型. 科技导报, 2004 , 22 (0402) : 17 -19 .

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    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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