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Adult male beagle dogs were randomly divided into a control group and two experimental groups, which receive either continuous exposure group or twice-weekly exposure to the magnetic field. Both experimental groups were exposed to the magnetic field for 4 weeks. Blood, urine, immune function, bone marrow smears, sperm quality, and morphology were assessed before and after irradiation. After the 4-week exposure, the dogs were sacrificed and the major organs were collected for pathological observation. Comprehensive analyses of these parameters showed that, except for a few indicators, there were no significant differences between the two experimental groups and the control group. The differences in the conventional indicators were within the normal range. Thus, exposure to an intermediate frequency magnetic field had no significant biological effects in beagle dogs, and there was no correlation between irradiation time or magnetic field with the biological effects. 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科技导报
| 研究论文 2010, 28(19): 86-92
中频磁场辐射全身毒性与安全性实验评价
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郭 静1,李 晓1,郭振东1,高晓娜1,冯 虹1,朱丽艳1,朱京丽3,洛小林3,唐劲天2
作者信息
1. 福州浩联医疗科技有限公司北京医疗研究中心,北京 1000852. 清华大学工程物理系;粒子技术与辐射成像教育部重点实验室,北京 1000843. 中日友好医院放疗科,北京 100029
通讯作者:
唐劲天
Experimental Evaluation of Systemic Toxicity and Safety of Exposure to Intermediate Frequency Alternating Magnetic Radiation
Affiliations
出版时间: 2010-10-13
文章导航
通过模拟临床试验条件对100kHz中频交变磁场进行安全性评价。选用成年雄性的比格犬,随机分为对照组、连续辐照组和一周辐照2次组。两辐照组均接受为期4周的辐照,分别于辐照前和辐照后进行血液检测、尿液检测、免疫指标检测、骨髓涂片、精子质量和形态检测。辐照后处死比格犬,取各主要脏器制成病理切片,进行病理观察。综合分析磁场的生物学影响。分析发现,两辐照组与对照组及两辐照组间除个别指标外大部分指标无显著差别,而有差别的指标也在常规检测的正常值范围内。结果表明,磁感应治疗机产生的中频磁场对生物体无显著的生物学影响,且辐照时间与磁场的生物学效应无相关关系。
We performed an experimental study to determine the safety and systemic toxicity of a 100-kHz intermediate frequency alternating magnetic field. Adult male beagle dogs were randomly divided into a control group and two experimental groups, which receive either continuous exposure group or twice-weekly exposure to the magnetic field. Both experimental groups were exposed to the magnetic field for 4 weeks. Blood, urine, immune function, bone marrow smears, sperm quality, and morphology were assessed before and after irradiation. After the 4-week exposure, the dogs were sacrificed and the major organs were collected for pathological observation. Comprehensive analyses of these parameters showed that, except for a few indicators, there were no significant differences between the two experimental groups and the control group. The differences in the conventional indicators were within the normal range. Thus, exposure to an intermediate frequency magnetic field had no significant biological effects in beagle dogs, and there was no correlation between irradiation time or magnetic field with the biological effects. These results provide evidence that intermediate frequency magnetic fields are safe and suitable for use in clinical trials.
medium frequency alternating magnetic field
/
irradiation
/
security
/
toxicity
郭 静;李 晓;郭振东;高晓娜;冯 虹;朱丽艳;朱京丽;洛小林;唐劲天.
中频磁场辐射全身毒性与安全性实验评价.
科技导报,
2010
, 28
(19)
: 86
-92
.
.
Experimental Evaluation of Systemic Toxicity and Safety of Exposure to Intermediate Frequency Alternating Magnetic Radiation[J].
Science & Technology Review ,
2010
, 28
(19)
: 86
-92
.
2010年第28卷第19期
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接收时间:2010-04-19
首发时间:2010-10-13
出版时间:2010-10-13
收稿日期:2010-04-19
修回日期:2010-09-29
https://castjournals.cast.org.cn/joweb/kjdb/CN/1242120688711041025
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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