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The four factors that influence the extraction result, the quantity and the concentration of alcohol, the extracting time and the frequency, were optimized. The extracting process is as follows: to extract twice with 55%, 65%, 75% alcohol, of amount of 10, 12, 14 times, 1.0, 1.5 and 2.0 hours each time. Then the L9(34) orthogonal design is used to find the best alcohol extraction technology of Gancao, Dijincao, Tiexianjue, Xiangqinglan. A balanced sampling is adopted in the range of each key factor to make each experiment highly representative. With the well-distributed nature of these factors, the orthogonal layout can ensure all experiments serve their purpose. The results show that the extracting time and amount do not have marked influence but the concentration of alcohol does. Due to the insignificant influence of the amount of alcohol and the extracting time, the optimum extraction technology A2B2C3 may be replaced by A2B1C1, that is, to extract twice with 65% alcohol, of amount of 10 times, 1 hour each time. The extraction method is reasonable, feasible and convenient to be applied to production. The preparation technology for Abnormal Savda Munziq Granular can be similarly obtained. , authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=ajxHYjsQ9CGCIbQlD55Hmg==, pdfFileSize=346356, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242120416957895235, articleId=1242120414508417521, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=异黑成熟颗粒醇提取工艺, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, 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科技导报
| 研究论文 2010, 28(15): 79-82
异黑成熟颗粒醇提取工艺
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古孜力努尔·依马木1,蒲 文2,薛桂蓬3,邢建国3,李 萧4,阿不都热依木·玉苏甫1
作者信息
1. 新疆医科大学维吾尔医药系,乌鲁木齐 8300112. 新疆医科大学第一附属医院,乌鲁木齐 8300113. 新疆维吾尔自治区药物研究所,乌鲁木齐 8300044. 新疆医科大学药学院,乌鲁木齐 830011
通讯作者:
阿不都热依木·玉苏甫
Alcohol Extraction Technology of Abnormal Savda Munziq Granular
Affiliations
出版时间: 2010-07-13
文章导航
为筛选异黑成熟颗粒中甘草、地锦草、铁线蕨和香青兰最佳的醇提取工艺,采用单因素试验,以甘草酸含量和醇浸出物量为指标,对影响提取效果的乙醇浓度A、提取时间B、乙醇用量C和提取次数D进行考查,确定提取次数为2次,选择乙醇浓度为55%、65%、75%,乙醇用量为10、12、14倍量,提取时间为1.0、1.5、2.0h。进一步采用L9(34)正交试验设计优选甘草、地锦草、铁线蕨和香青兰醇提取条件,对实验各关键因素变化范围内均衡抽样,使每次试验都具有较强的代表性。结果表明,乙醇浓度对提取效果有显著影响,而提取时间、乙醇用量对提取效果无显著性影响,最佳提取工艺为A2B2C3。鉴于乙醇用量和提取时间对提取效果无显著性影响,为降低成本、节省工时,将B2改为B1,将C3改为C1,由此得提取工艺为A2B1C1。确定药材醇提取条件:65%乙醇10倍量,提取2次,每次1h。由此,经过正交试验法优选的提取工艺设计合理,结果稳定可行,符合大工业生产要求。上述实验结果可为异黑成熟颗粒制备工艺的确定提供实验依据。
To develop the optimal alcohol extraction technology of Gancao, Dijincao, Tiexianjue in the Abnormal Savda Munziq Granula, with the content and the amount of alcohol extractive of glycyrrhizin as index, single factor experiments were carried out. The four factors that influence the extraction result, the quantity and the concentration of alcohol, the extracting time and the frequency, were optimized. The extracting process is as follows: to extract twice with 55%, 65%, 75% alcohol, of amount of 10, 12, 14 times, 1.0, 1.5 and 2.0 hours each time. Then the L9(34) orthogonal design is used to find the best alcohol extraction technology of Gancao, Dijincao, Tiexianjue, Xiangqinglan. A balanced sampling is adopted in the range of each key factor to make each experiment highly representative. With the well-distributed nature of these factors, the orthogonal layout can ensure all experiments serve their purpose. The results show that the extracting time and amount do not have marked influence but the concentration of alcohol does. Due to the insignificant influence of the amount of alcohol and the extracting time, the optimum extraction technology A2B2C3 may be replaced by A2B1C1, that is, to extract twice with 65% alcohol, of amount of 10 times, 1 hour each time. The extraction method is reasonable, feasible and convenient to be applied to production. The preparation technology for Abnormal Savda Munziq Granular can be similarly obtained.
abnormal Savda Munziq granular
/
single factor
/
orthogona
古孜力努尔·依马木;蒲 文;薛桂蓬;邢建国;李 萧;阿不都热依木·玉苏甫.
异黑成熟颗粒醇提取工艺.
科技导报,
2010
, 28
(15)
: 79
-82
.
.
Alcohol Extraction Technology of Abnormal Savda Munziq Granular[J].
Science & Technology Review ,
2010
, 28
(15)
: 79
-82
.
2010年第28卷第15期
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接收时间:2010-05-26
首发时间:2010-07-13
出版时间:2010-07-13
收稿日期:2010-05-26
修回日期:2010-08-05
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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