Article(id=1242120256060194945, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242120230915346576, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1273420800000, receivedDateStr=2010-05-10, revisedDate=1274976000000, revisedDateStr=2010-05-28, acceptedDate=null, acceptedDateStr=null, onlineDate=1278950400000, onlineDateStr=2010-07-13, pubDate=1278950400000, pubDateStr=2010-07-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1278950400000, onlineIssueDateStr=2010-07-13, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774074146520, creator=sys-migrate, updateTime=1774074146520, updator=sys-migrate, issue=Issue{id=1242120230915346576, tenantId=1146029695717560320, journalId=1146031591421210625, year='2010', volume='28', issue='13', pageStart='3', pageEnd='139', issueExtLink='null', onlineDate='null', pubDate='1278950400000', pubDateStr='2010-07-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774074140524, creator='sys-migrate', updateTime=1774074140524, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=87, endPage=91, ext={EN=ArticleExt(id=1242120266638229680, articleId=1242120256060194945, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Effects of X-ray on Histological Structure and Interrelated Polypeptides in Liver of Filial Mice, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=To explore the effects of X-ray on weight,histological structure and expression of Bax protein in liver of developing filial mice,160 mice of 6~7 days after birth were radiated with different dosages (0, 1, 3, 5, 7Gy) of X-ray. Changes of liver and body weight were examined, histological structure was observed using bio-microscopy,and the expression of Bax protein was measured by immunohistochemical staining in filial mice liver at 1, 5, 10 and 20d after irradiation. Results show that X-ray influences the growth and development of the filial mice liver. The liver weight of filial mice of the experimental groups is lower than that of the control group 5~20d after irradiation (P<0.05 or P<0.01), except experimental groups with 1Gy; the body weight of filial mice of the experimental groups is lower than that of the control group 5~20d after irradiation(P<0.01); the expression intensity of Bax protein in the liver of filial mice is significantly increased with the increase of the dose; the structure of hepatic lobule is unclear, hepatic plate is thinner, hepatic sinusoid is stronger, accompanied with hepatocyte disfiguration, irregular arrangement, nucleus atrophy, and vacuolization, after irradiation., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=tPJKuhjgWdA8dRi5LyBPPQ==, pdfFileSize=6058818, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242120263953875112, articleId=1242120256060194945, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=X射线辐射对仔鼠肝组织结构和相关蛋白的影响, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=为探讨X射线辐射对仔鼠肝重量、肝组织结构及肝中Bax蛋白表达的影响,对160只仔鼠(出生6~7d),用不同剂量(0、1、3、5、7Gy)的X射线进行全身辐射,分别于辐射后1、5、10、20d,检测各期仔鼠肝重和体重的变化,用显微技术观察仔鼠肝脏组织结构的变化,用免疫组织化学方法检测肝脏中Bax蛋白的表达。结果表明,X射线辐射影响仔鼠肝脏的生长发育,辐射后5~20d,辐射组仔鼠肝重均低于对照组,差异显著(P<0.05)或极显著(P<0.01);除1Gy辐射组外,其他辐射组在5~20d时仔鼠体重均低于对照组,差异极显著(P<0.01);随辐射剂量增大,辐射组仔鼠肝中Bax蛋白阳性表达逐渐增强;辐射后仔鼠肝小叶结构不清,肝板变细,肝血窦变大,肝细胞变形,排列不规则,细胞核萎缩,细胞出现空泡化。, authors=刘曜荣1,2,俞诗源2, authorsList=刘曜荣;俞诗源, authorCompany=1. 西北师范大学附属中学,兰州 7300702. 西北师范大学生命科学学院,兰州 730070, correspAuthors=null, authorNote=null, correspAuthorsNote=俞诗源, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=fTqqbVIi50yjcXKjdekLjQ==, pdfFileSize=6058818, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=[Author(id=1278907465647505998, tenantId=1146029695717560320, journalId=null, articleId=1242120256060194945, orderNo=null, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=null, authorType=null, ext={CN=AuthorExt(id=null, tenantId=null, journalId=1146031591421210625, articleId=1242120256060194945, authorId=1278907465647505998, language=CN, stringName=刘曜荣;俞诗源, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=null, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=null)], keywords=[Keyword(id=1242120261621842079, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=CN, orderNo=1, keyword=X射线), Keyword(id=1242120263488307361, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=CN, orderNo=1, keyword=仔鼠), Keyword(id=1242120263647690914, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=CN, orderNo=1, keyword=肝), Keyword(id=1242120263735771301, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=CN, orderNo=1, keyword=组织结构), Keyword(id=1242120263815463078, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=CN, orderNo=1, keyword=Bax蛋白), Keyword(id=1242120266109747370, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=EN, orderNo=1, keyword=X-ray), Keyword(id=1242120266189439148, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=EN, orderNo=1, keyword=filial mice), Keyword(id=1242120266277519533, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=EN, orderNo=1, keyword=liver), Keyword(id=1242120266373988526, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=EN, orderNo=1, keyword=histological structure), Keyword(id=1242120266487234735, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242120256060194945, language=EN, orderNo=1, keyword=Bax protein)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1125356956822126595, delFlag=0, nameCn=科技导报, nameEn=Science & Technology Review, nameHistory1=null, nameHistory2=null, issn=1000-7857, eissn=, cn=11-1421/N, coden=null, periodic=3, language=CN, oaType=0, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=wfghvu3bhh/dKxuZ+ucVHA==, journalPrice=null, startedYear=null, abbrevIsoEn=Sci Technol Rev, journalRemark=null, publicationField=null, createdTime=null, updatedTime=1774230116083, createdBy=null, updatedBy=13041195026, firstLetterCn=S, firstLetterEn=S, subjectCode=Natural Sciences, subjectName=自然科学, subjectCodeEn=Natural Sciences, subjectNameEn=null, picCn=wfghvu3bhh/dKxuZ+ucVHA==, picEn=yjSfclmpNm7ihn9NbTZ69g==, jcr=null, cjcr=null, exts=[JournalExt(id=1242774439910290156, language=CN, name=科技导报, nameHistory1=null, nameHistory2=null, managedBy=中国科学技术协会, sponsoredBy=中国科学技术协会, publishedBy=科技导报社, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/CN/home, createdTime=1774230116107, updatedTime=1774230116107, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/CN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.cast.org.cn/webm, submissionEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionReviewUrl=https://kjdbauthor.cast.org.cn/webm, submissionCeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionAeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, option={"copyright":""}), JournalExt(id=1242774439960621805, language=EN, name=Science & Technology Review, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/EN/home, createdTime=1774230116119, updatedTime=1774230116119, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/EN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionReviewUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionCeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionAeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, option={"copyright":""})], databaseList=null, tenantJournalId=1146031591421210625, websiteList=[Website(id=1146104741081231361, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/CN, language=CN, createTime=1751182263881, createBy=18614031015, updateTime=1751778001962, updateBy=18614031015, name=科技导报, tplId=1146099689490845704, title=科技导报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1148021146403992296, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=articleTextType, value=kx, createTime=1751639170504, updateTime=1751639170504, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146378826469, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=banner, value=null, createTime=1751639170498, updateTime=1751639170498, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146366243556, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1751639170495, updateTime=1751639170495, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146395603687, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic, createTime=1751639170502, updateTime=1751639170502, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146387215078, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1751639170500, updateTime=1751639170500, creator=18614031015, updator=18614031015)]), Website(id=1146105254833139715, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/EN, language=EN, createTime=1751182386363, createBy=18614031015, updateTime=1753500121937, updateBy=18614031015, name=科技导报, tplId=1146101810881728533, title=Science & Technology Review, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1155838567709528217, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=articleTextType, value=kx, createTime=1753502988984, updateTime=1753502988984, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567692750998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=banner, value=null, createTime=1753502988980, updateTime=1753502988980, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567688556693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1753502988979, updateTime=1753502988979, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567705333912, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic, createTime=1753502988983, updateTime=1753502988983, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567701139607, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1753502988982, updateTime=1753502988982, creator=18614031015, updator=18614031015)])], journalTitle=科技导报, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Science & Technology Review, journalPhotoCn=wfghvu3bhh/dKxuZ+ucVHA==, journalPhotoEn=yjSfclmpNm7ihn9NbTZ69g==, journalFirstLetter=S, journalRecommend=null, journalNew=null, journalCollection=1, jcrJf=null, cjcrJf=0.91, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=null, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/Y2010/V28/I13/87, detailUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/Y2010/V28/I13/87, pdfUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/PDF/Y2010/V28/I13/87, pdfUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/PDF/Y2010/V28/I13/87, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1278950400000, fullTextJson=null, articleText=null, reference=null)
收藏切换
X射线辐射对仔鼠肝组织结构和相关蛋白的影响
收藏切换
PDF下载
刘曜荣;俞诗源
科技导报 | 研究论文 2010,28(13): 87-91
收起
收藏切换
科技导报 | 研究论文 2010, 28(13): 87-91
X射线辐射对仔鼠肝组织结构和相关蛋白的影响
全屏
刘曜荣;俞诗源
作者信息

通讯作者:

俞诗源
Effects of X-ray on Histological Structure and Interrelated Polypeptides in Liver of Filial Mice
Affiliations
出版时间: 2010-07-13
文章导航
收藏切换
为探讨X射线辐射对仔鼠肝重量、肝组织结构及肝中Bax蛋白表达的影响,对160只仔鼠(出生6~7d),用不同剂量(0、1、3、5、7Gy)的X射线进行全身辐射,分别于辐射后1、5、10、20d,检测各期仔鼠肝重和体重的变化,用显微技术观察仔鼠肝脏组织结构的变化,用免疫组织化学方法检测肝脏中Bax蛋白的表达。结果表明,X射线辐射影响仔鼠肝脏的生长发育,辐射后5~20d,辐射组仔鼠肝重均低于对照组,差异显著(P<0.05)或极显著(P<0.01);除1Gy辐射组外,其他辐射组在5~20d时仔鼠体重均低于对照组,差异极显著(P<0.01);随辐射剂量增大,辐射组仔鼠肝中Bax蛋白阳性表达逐渐增强;辐射后仔鼠肝小叶结构不清,肝板变细,肝血窦变大,肝细胞变形,排列不规则,细胞核萎缩,细胞出现空泡化。
X射线  /  仔鼠  /  肝  /  组织结构  /  Bax蛋白
To explore the effects of X-ray on weight,histological structure and expression of Bax protein in liver of developing filial mice,160 mice of 6~7 days after birth were radiated with different dosages (0, 1, 3, 5, 7Gy) of X-ray. Changes of liver and body weight were examined, histological structure was observed using bio-microscopy,and the expression of Bax protein was measured by immunohistochemical staining in filial mice liver at 1, 5, 10 and 20d after irradiation. Results show that X-ray influences the growth and development of the filial mice liver. The liver weight of filial mice of the experimental groups is lower than that of the control group 5~20d after irradiation (P<0.05 or P<0.01), except experimental groups with 1Gy; the body weight of filial mice of the experimental groups is lower than that of the control group 5~20d after irradiation(P<0.01); the expression intensity of Bax protein in the liver of filial mice is significantly increased with the increase of the dose; the structure of hepatic lobule is unclear, hepatic plate is thinner, hepatic sinusoid is stronger, accompanied with hepatocyte disfiguration, irregular arrangement, nucleus atrophy, and vacuolization, after irradiation.
X-ray  /  filial mice  /  liver  /  histological structure  /  Bax protein
刘曜荣;俞诗源. X射线辐射对仔鼠肝组织结构和相关蛋白的影响. 科技导报, 2010 , 28 (13) : 87 -91 .
. Effects of X-ray on Histological Structure and Interrelated Polypeptides in Liver of Filial Mice[J]. Science & Technology Review, 2010 , 28 (13) : 87 -91 .
2010年第28卷第13期
PDF下载
272
152
引用本文
BibTeX
文章信息
  • 接收时间:2010-05-10
  • 首发时间:2010-07-13
  • 出版时间:2010-07-13
补充材料
相关文章
文章信息
作者
出版历史
  • 收稿日期:2010-05-10
  • 修回日期:2010-05-28
基金
作者信息

通讯作者:

俞诗源
参考文献
分享链接
https://castjournals.cast.org.cn/joweb/kjdb/CN/1242120256060194945
分享至
全文二维码

扫描看全文

引用本文
BibTeX
本文的引用情况
2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏