Article(id=1242119971430531508, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242117114744607287, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1258905600000, receivedDateStr=2009-11-23, revisedDate=1263830400000, revisedDateStr=2010-01-19, acceptedDate=null, acceptedDateStr=null, onlineDate=1273680000000, onlineDateStr=2010-05-13, pubDate=1273680000000, pubDateStr=2010-05-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1273680000000, onlineIssueDateStr=2010-05-13, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774074078659, creator=sys-migrate, updateTime=1774074078659, updator=sys-migrate, issue=Issue{id=1242117114744607287, tenantId=1146029695717560320, journalId=1146031591421210625, year='2010', volume='28', issue='09', pageStart='3', pageEnd='139', issueExtLink='null', onlineDate='null', pubDate='1273680000000', pubDateStr='2010-05-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774073397570, creator='sys-migrate', updateTime=1774073397570, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=84, endPage=88, ext={EN=ArticleExt(id=1242119974844699351, articleId=1242119971430531508, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Effect of Uygur Foeniculum Vulgare Mill on Transfer Growth Factor-β1 of Experimental Hepatic Fibrosis Rats, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=To study the effect of Uygur Foeniculum vulgare Mill on Transfer Growth Factor -β1 (TGF-β1) of experimental hepatic fibrosis rats, 48 Wistar rats were divided into 4 groups randomly, i.e., the normal control group, the model group, the colchicines group, and the Uygur Foeniculum vulgare Mill group. All rats except for those in the normal control group were induced with 2mL/kg carbon tetrachloride. Uygur Foeniculum vulgare Mill group and colchicines group were treated with 100mg/kg Uygur Foeniculum vulgare Mill and 0.2mg/kg colchicines, respectively, for 6 weeks. Live tissue of hepatic fibrosis was extirpated for pathologic examination with Hematoxylin-Eosin (HE) stains and expression of TGF-β1 with immunohistochemistry stain. The results show that the degree of hepatic fibrosis in the Foeniculum vulgare Mill preventive group was improved significantly as seen from staining of HE. The expression of TGF-β1 in the model group was in a higher level than that in the normal group (P<0.01). But the expression level of TGF-β1 in the Foeniculum vulgare Mill group was lower than that in the model group. It is inferred that Foeniculum vulgare Mill can be used to prevent rat hepatic fibrosis by reducing expression of TGF-β1 and to improve hepatic functions., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=Ouqgk1pelwf0+G5jp6ljeQ==, pdfFileSize=1214313, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242119974068748736, articleId=1242119971430531508, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=维吾尔药小茴香对肝纤维化大鼠转化生长因子-β1的影响, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=观察维吾尔药小茴香对实验性大鼠肝纤维化转化生长因子-β1（TGF-β1）的影响，探讨其抗肝纤维化作用及其机制。选取健康Wistar大鼠48只，随机分为正常对照组、肝纤维化模型组、维吾尔药小茴香组、秋水仙碱组，共4组，每组12只。除正常对照组外，其他各组均腹腔注射40%的四氯化碳油造模剂2mL/kg，药物干预组造模，同时分别给予维吾尔药小茴香100mg/kg和秋水仙碱0.2mg/kg，持续6周。各组大鼠留取肝组织进行病理学观察和TGF-β1免疫组化染色。结果显示，小茴香可显著降低给药组大鼠TGF-β1表达水平（P<0.01），小茴香组大鼠肝纤维化程度较模型组明显改善，表明维吾尔药小茴香具有明显的抗肝纤维化作用，并可降低实验性大鼠TGF-β1水平。, authors=^{吴小川1,2，马秀敏1,2，薛志琴2，朱玥洁2，马 骏3，侯 敏1,2，薛 洁1，丁剑冰1,2}, authorsList=吴小川;马秀敏;薛志琴;朱玥洁;马 骏;侯 敏;薛 洁;丁剑冰;, authorCompany=1. 新疆医科大学新疆中维药药学重点实验室，乌鲁木齐 8300112. 新疆医科大学基础医学院，乌鲁木齐 8300113. 新疆医科大学附属中医医院，乌鲁木齐 830000, correspAuthors=null, authorNote=null, correspAuthorsNote=丁剑冰, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=qo4sYHRowNTTWHpwRq/aUg==, pdfFileSize=1214313, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, 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