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The height, weight, DBP, SBP and waist circumference of both groups were recorded and SUA, TG, TC, HDL, LDL, FPG and FINS were determined. The FINS was measured with radioimmunoassy (RIA). The HOMA-IR was calculated based on FPG and FINS with the minimal model. The statistical data were analyzed by SPSS 16.0 software. Results show that for the hyperuricemia group, as compared with the control group, the FINS levels are increased significantly ((27.85±19.56)μIU/mL vs (18.38±10.33)μIU/mL, P<0.01), the HOMA-IR is significantly higher ((8.38±7.96) vs (4.08±2.44), P<0.01), the HbA1c levels and FPG levels are also significantly increased ((6.29%±1.81%) vs (4.94%±0.43%), P<0.01), ((6.38±2.68)mmol/L vs (4.96±0.56)mmol/L , P<0.01). The multiple stepwise regression analysis shows that the SUA levels are related to BMI, HbA1c, TG and HDL, a positive correlation between SUA levels and TG (r=0.321, P<0.01), FPG (r=0.207, P<0.01), HbA1c(r=0.353, P<0.01), INS(r=0.337, P<0.01), HOMA-IR (r=0.315, P<0.01), but a negative correlation with HDL in two groups. It is concluded that hyperuricemia is correlated with abnormal blood glucose levels and the insulin resistance., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=mxQS64Btv0YePli/e+tWKQ==, pdfFileSize=387397, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242119470093766787, articleId=1242119467254219719, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=新疆汉族血尿酸水平与糖代谢指标之间的情况分析, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=为了探讨新疆汉族血尿酸（SUA）水平与糖代谢相关指标之间的关系，随机抽取新疆医科大学第一附属医院汉族住院病人301例为研究对象，其中高尿酸组149例，尿酸正常组152例。血清检测血尿酸（SUA）及血糖相关指标。检测人体测量参数，用放射免疫法（RIA）测定空腹血清胰岛素（FINS），并计算稳态模型胰岛素抵抗（HOMA-IR）指数。结果显示：① FINS水平，高尿酸血症组（27.85±19.56）μIU/mL明显高于对照组（18.38±10.33）μIU/mL，P<0.01；HOMA-IR，高尿酸血症组（8.38±7.96）明显高于对照组（4.08±2.44），P<0.01；糖化血红蛋白（HbA1c）水平，高尿酸血症组（6.29%±1.81%）明显高于对照组（4.94%±0.43%），P<0.01；空腹血糖（FPG）水平，高尿酸血症组（6.38±2.68）mmol/L明显高于对照组（4.96±0.56）mmol/L，P<0.01。② 研究对象的SUA水平与甘油三酯（TG）（r=0.321，P<0.01）、FPG（r=0.207，P<0.01）、HbA1c（r=0.353，P<0.01）、FINS（r=0.337，P<0.01）、HOMA-IR（r=0.315，P<0.01）呈显著正相关，与高密度脂蛋白（HDL）（r=-0.147，P<0.01）呈显著负相关。③ 多元逐步回归分析显示，体质指数（BMI）、HbA1c、TG和HDL是影响血尿酸的主要相关因素。研究表明，高尿酸血症患者存在糖代谢异常及胰岛素抵抗。, authors=肖明1 ,姚华2 ,伊惠霞2 , authorsList=肖明;姚华;伊惠霞, authorCompany=1. 新疆医科大学公共卫生学院，乌鲁木齐 8300542. 新疆医科大学第一附属医院，乌鲁木齐 830054, correspAuthors=null, authorNote=null, correspAuthorsNote=肖明, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, 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科技导报
|研究论文
2010
, 28
(1002) :
30
-33
新疆汉族血尿酸水平与糖代谢指标之间的情况分析
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肖明1 ,姚华2 ,伊惠霞2
作者信息
1. 新疆医科大学公共卫生学院，乌鲁木齐 8300542. 新疆医科大学第一附属医院，乌鲁木齐 830054
通讯作者:
肖明
Correlation between serum uric acid and related indexes of glucose metabolism in Han ethnic population of Xinjiang.
Affiliations
出版时间: 2010-01-28
文章导航
为了探讨新疆汉族血尿酸（SUA）水平与糖代谢相关指标之间的关系，随机抽取新疆医科大学第一附属医院汉族住院病人301例为研究对象，其中高尿酸组149例，尿酸正常组152例。血清检测血尿酸（SUA）及血糖相关指标。检测人体测量参数，用放射免疫法（RIA）测定空腹血清胰岛素（FINS），并计算稳态模型胰岛素抵抗（HOMA-IR）指数。结果显示：① FINS水平，高尿酸血症组（27.85±19.56）μIU/mL明显高于对照组（18.38±10.33）μIU/mL，P<0.01；HOMA-IR，高尿酸血症组（8.38±7.96）明显高于对照组（4.08±2.44），P<0.01；糖化血红蛋白（HbA1c）水平，高尿酸血症组（6.29%±1.81%）明显高于对照组（4.94%±0.43%），P<0.01；空腹血糖（FPG）水平，高尿酸血症组（6.38±2.68）mmol/L明显高于对照组（4.96±0.56）mmol/L，P<0.01。② 研究对象的SUA水平与甘油三酯（TG）（r=0.321，P<0.01）、FPG（r=0.207，P<0.01）、HbA1c（r=0.353，P<0.01）、FINS（r=0.337，P<0.01）、HOMA-IR（r=0.315，P<0.01）呈显著正相关，与高密度脂蛋白（HDL）（r=-0.147，P<0.01）呈显著负相关。③ 多元逐步回归分析显示，体质指数（BMI）、HbA1c、TG和HDL是影响血尿酸的主要相关因素。研究表明，高尿酸血症患者存在糖代谢异常及胰岛素抵抗。
To investigate the correlation between serum uric acid and related indexes of glucose metabolism, 301 blood samples were collected from a hospital, among which 149 are from hyperuricemia patients as the hyperuricemia group and 152 are from healthy subjects as the control group. The height, weight, DBP, SBP and waist circumference of both groups were recorded and SUA, TG, TC, HDL, LDL, FPG and FINS were determined. The FINS was measured with radioimmunoassy (RIA). The HOMA-IR was calculated based on FPG and FINS with the minimal model. The statistical data were analyzed by SPSS 16.0 software. Results show that for the hyperuricemia group, as compared with the control group, the FINS levels are increased significantly ((27.85±19.56)μIU/mL vs (18.38±10.33)μIU/mL, P<0.01), the HOMA-IR is significantly higher ((8.38±7.96) vs (4.08±2.44), P<0.01), the HbA1c levels and FPG levels are also significantly increased ((6.29%±1.81%) vs (4.94%±0.43%), P<0.01), ((6.38±2.68)mmol/L vs (4.96±0.56)mmol/L , P<0.01). The multiple stepwise regression analysis shows that the SUA levels are related to BMI, HbA1c, TG and HDL, a positive correlation between SUA levels and TG (r=0.321, P<0.01), FPG (r=0.207, P<0.01), HbA1c(r=0.353, P<0.01), INS(r=0.337, P<0.01), HOMA-IR (r=0.315, P<0.01), but a negative correlation with HDL in two groups. It is concluded that hyperuricemia is correlated with abnormal blood glucose levels and the insulin resistance.
hyperuricemia
/
glucose metabolism
/
insulin resistance
肖明;姚华;伊惠霞.
新疆汉族血尿酸水平与糖代谢指标之间的情况分析.
科技导报,
2010
, 28
(1002)
: 30
-33
.
.
Correlation between serum uric acid and related indexes of glucose metabolism in Han ethnic population of Xinjiang.[J].
Science & Technology Review ,
2010
, 28
(1002)
: 30
-33
.
2010年第28卷第1002期
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接收时间：2009-10-13
首发时间：2010-01-28
出版时间：2010-01-28
收稿日期：2009-10-13
修回日期：2009-12-25
https://castjournals.cast.org.cn/joweb/kjdb/CN/1242119467254219719
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2种不同金属材料的力学参数
科 属数 种数 占总种数比例 属 种数 占总种数比例 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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