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To provide a basis for the natural medicine to be used for the prevention of dental caries, SPF-SD rats infected with Streptococcus mutans were selected. The caries 2000#, with distilled water, infusion Turkish gall, NaF and CHX solution, as well as the Turkish gall+NaF mixture, respectively, were applied to 5 groups of rats by painting their mouth. The collected rat saliva was cultured, the levels of Streptococcus mutans and dental caries score of Keyes were recorded to see the effects of Turkish gall on the rat growth and reproduction of Streptococcus mutans in their mouth and to evaluate the effects of drugs in inhibiting the formation of caries. The results show that (1) Streptococcus mutans level: as compared with the distilled water, there is a decrease to different extents for all strains, but only for NaF and CHX groups there is a significant difference (P<0.05); (2) caries scores of Keyes: the experimental groups of drugs all show some inhibition effects on the formation of dental caries in rats in varying degrees, of which Turkish gall shows good effects on sulcal-surface and smooth-surface caries (P<0.05), but they are all lower than the NaF group; Turkish gall+NaF group has no obvious role in the synergistic inhibition of caries. The natural medicine Turkish gall inhibits rat oral Streptococcus mutans growth and metabolism, which effectively prevents the occurrence of dental caries., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=ZHAO Jin, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=kUyypl50v7uQMUNG7OmQKg==, pdfFileSize=644006, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242119350631596625, articleId=1242119348551221822, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=天然药物没食子和联合氟制剂预防龋病的动物实验研究, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=通过动物实验观察天然药物没食子(Turkish gall)和联合氟制剂预防龋病的效果,为天然药物没食子预防龋病的临床研究提供了理论和试验依据。选用SPF-SD大鼠感染致龋细菌,饲以致龋饲料2000#,分别用蒸馏水、没食子浸剂、氟化钠溶液、洗必泰溶液以及没食子+氟化钠混合液连续5周给5组大鼠口腔涂药,采集大鼠唾液培养,记录变形链球菌水平及龋齿Keyes记分,观察没食子和没食子+氟化钠对大鼠口腔内变形链球菌生长繁殖的影响并评估药物抑制龋损形成的效果。结果显示:① 对于变形链球菌水平,与蒸馏水组相比,其余各组菌量均有不同程度的降低,只有氟化钠组和洗必泰组与蒸馏水组比较有统计学差异(P<0.05);② 对于龋齿Keyes记分,各实验组药物对大鼠龋齿的形成及严重程度均有不同程度的抑制,其中没食子显示对窝沟面龋和光滑面龋有较好的防治效果(P<0.05),但均低于氟化钠组;没食子+氟化钠组未见明显的协同抑龋作用。表明天然药物没食子能抑制大鼠口腔变链菌的生长代谢,可有效预防龋齿的发生。, authors=牛巧丽1,哈木拉提·吾甫尔2,赵今1,努尔比亚·买买提依明1, authorsList=牛巧丽;哈木拉提·吾甫尔;赵今;努尔比亚·买买提依明, authorCompany=1. 新疆医科大学第一附属医院口腔科,乌鲁木齐 8300542. 新疆医科大学维吾尔医药系,乌鲁木齐 830054, correspAuthors=null, authorNote=null, correspAuthorsNote=赵今, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=zooqFbg3ZJyF2WO7lAVNUQ==, pdfFileSize=644006, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, 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天然药物没食子和联合氟制剂预防龋病的动物实验研究
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科技导报 |研究论文 2009 , 27 (0924) : 61 -66
天然药物没食子和联合氟制剂预防龋病的动物实验研究
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赵今
Effects of Natural Medicine Turkish Gall and the Union Fluorine on Caries Development in Rats
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    ZHAO Jin
出版时间: 2009-12-28
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通过动物实验观察天然药物没食子(Turkish gall)和联合氟制剂预防龋病的效果,为天然药物没食子预防龋病的临床研究提供了理论和试验依据。选用SPF-SD大鼠感染致龋细菌,饲以致龋饲料2000#,分别用蒸馏水、没食子浸剂、氟化钠溶液、洗必泰溶液以及没食子+氟化钠混合液连续5周给5组大鼠口腔涂药,采集大鼠唾液培养,记录变形链球菌水平及龋齿Keyes记分,观察没食子和没食子+氟化钠对大鼠口腔内变形链球菌生长繁殖的影响并评估药物抑制龋损形成的效果。结果显示:① 对于变形链球菌水平,与蒸馏水组相比,其余各组菌量均有不同程度的降低,只有氟化钠组和洗必泰组与蒸馏水组比较有统计学差异(P<0.05);② 对于龋齿Keyes记分,各实验组药物对大鼠龋齿的形成及严重程度均有不同程度的抑制,其中没食子显示对窝沟面龋和光滑面龋有较好的防治效果(P<0.05),但均低于氟化钠组;没食子+氟化钠组未见明显的协同抑龋作用。表明天然药物没食子能抑制大鼠口腔变链菌的生长代谢,可有效预防龋齿的发生。
龋病  /  没食子  /  动物模型  /  变形链球菌
Based on the experimental observation of animal, the effects of the natural medicines Turkish gall and the union fluorine on dental caries prevention are studied. To provide a basis for the natural medicine to be used for the prevention of dental caries, SPF-SD rats infected with Streptococcus mutans were selected. The caries 2000#, with distilled water, infusion Turkish gall, NaF and CHX solution, as well as the Turkish gall+NaF mixture, respectively, were applied to 5 groups of rats by painting their mouth. The collected rat saliva was cultured, the levels of Streptococcus mutans and dental caries score of Keyes were recorded to see the effects of Turkish gall on the rat growth and reproduction of Streptococcus mutans in their mouth and to evaluate the effects of drugs in inhibiting the formation of caries. The results show that (1) Streptococcus mutans level: as compared with the distilled water, there is a decrease to different extents for all strains, but only for NaF and CHX groups there is a significant difference (P<0.05); (2) caries scores of Keyes: the experimental groups of drugs all show some inhibition effects on the formation of dental caries in rats in varying degrees, of which Turkish gall shows good effects on sulcal-surface and smooth-surface caries (P<0.05), but they are all lower than the NaF group; Turkish gall+NaF group has no obvious role in the synergistic inhibition of caries. The natural medicine Turkish gall inhibits rat oral Streptococcus mutans growth and metabolism, which effectively prevents the occurrence of dental caries.
caries  /  Turkish gall  /  animal model  /  Streptococcus mutans
牛巧丽;哈木拉提·吾甫尔;赵今;努尔比亚·买买提依明. 天然药物没食子和联合氟制剂预防龋病的动物实验研究. 科技导报, 2009 , 27 (0924) : 61 -66 .
. Effects of Natural Medicine Turkish Gall and the Union Fluorine on Caries Development in Rats[J]. Science & Technology Review, 2009 , 27 (0924) : 61 -66 .

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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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