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科技导报
|研究论文
2005
, 23
(0511) :
50
-53
真菌多糖AbEXP1-a的结构及其免疫调节活性研究
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张卉
作者信息
Study on Chemical Structure and Immunomodulating Activity of Fungal Polysaccharide AbEXP 1-a
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出版时间: 2005-11-10
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采用酸水解法、红外光谱法和核磁共振法对真菌多糖AbEXP1-a的结构进行了研究,并对该多糖的免疫调节活性进行了动物实验检测。结果表明,多糖AbEXP1-a分子由葡萄糖和甘露糖以3:1的比例构成。推测其主链由3个葡萄糖分子通过β-(1→6)糖苷键连在一起,再以α-(1→6)或β-(1→6)糖苷键与甘露糖连接而构成。多糖AbEXP1-a对小鼠非特异性免疫、体液免疫和细胞免疫均有明显的促进作用,可提高小鼠迟发性变态反应,即多糖AbEXP1-a可以全面提高机体的免疫功能。其最适作用剂量为10mg/kg体重。
The chemical structure of fungal polysaccharide AbEXP 1-a was studied through acid hydrolysis, IR spectroscopy and NMR spectroscopy. And its immunomodulating activity was tested through animal experiments. The results are as follow: AbEXP 1-a is consisted of glucose and mannose in ratio of 3:1. Its backbone was deduced that consisted of 3 glucoses combined by β-(1→6) glycosidic linkage and a meanose linking to them through α-(1→6) or β-(1→6) glycosidic linkage. AbEXP 1-a was found to be capable of promoting non-specific immunity, humoral immunity and cellular immunity of mice. Besides, it also could promote delayed type hypersensitivity in mice. All that means that AbEXP 1a could enhance the immunity of organisms comprehensively and the appropriate dosage is 10 mg/kg body weight.
microorganism engineering
/
fungal polysaccharide
/
chemical structure
/
immunomodulating
张卉.
真菌多糖AbEXP1-a的结构及其免疫调节活性研究.
科技导报,
2005
, 23
(0511)
: 50
-53
.
.
Study on Chemical Structure and Immunomodulating Activity of Fungal Polysaccharide AbEXP 1-a[J].
Science & Technology Review ,
2005
, 23
(0511)
: 50
-53
.
2005年第23卷第0511期
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接收时间:2009-08-25
首发时间:2005-11-10
出版时间:2005-11-10
收稿日期:2009-08-25
修回日期:1900-01-01
https://castjournals.cast.org.cn/joweb/kjdb/CN/1242118984183644313
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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