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科技导报
|研究论文
2006
, 24
(0602) :
43
-46
乳酸杆菌通过定植和提供免疫信号调节宿主免疫反应
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孙进1 ,施用晖1，2 ,马西艺1 ,苏广伟1
作者信息
1. 江南大学食品学院食品营养与安全研究所 江苏无锡2. 江南大学教育部食品科学和安全重点实验室 江苏无锡
Lactobacillus Modulate Host Immune Response through Colonization and Provision of Immune Signals
Affiliations
出版时间: 2006-02-10
文章导航
提取了Lactobacillussp.的肽聚糖,用AffymetrixMOE430A基因芯片研究了肽聚糖对机体免疫细胞基因表达的影响。结果发现,乳酸杆菌肽聚糖可以刺激免疫细胞Th1型免疫反应相关基因的表达,可能激活TLR-NF-κB相关信号通路,同时,不同剂量的肽聚糖可能通过调节Tollip的表达,影响TLR-NF-κB信号通路的激活,从而调节细胞因子的表达。
Peptidoglycan(PG) was prepared from Lactobacillus sp. Effects of Lactobacillus sp. PG on gene expression of mice immunocytes were studied by using Affymetrix MOE430A Genechip. PG was found inducing expression of molecules related to type 1 immune response. TLR-NF-κB signal pathway would be activated. The expression of Tollip, a negative regulator of TLR-NF-κB signal pathway was modulated by different doses of PG, which could lead to different expressions of different cytikons.
孙进;施用晖;马西艺;苏广伟.
乳酸杆菌通过定植和提供免疫信号调节宿主免疫反应.
科技导报,
2006
, 24
(0602)
: 43
-46
.
.
Lactobacillus Modulate Host Immune Response through Colonization and Provision of Immune Signals[J].
Science & Technology Review ,
2006
, 24
(0602)
: 43
-46
.
2006年第24卷第0602期
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文章信息
接收时间：2009-03-30
首发时间：2006-02-10
出版时间：2006-02-10
收稿日期：2009-03-30
修回日期：1900-01-01
https://castjournals.cast.org.cn/joweb/kjdb/CN/1242118137869570329
引用本文
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2种不同金属材料的力学参数
科 属数 种数 占总种数比例 属 种数 占总种数比例 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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