Article(id=1242118071163355767, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242117794456732041, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1241452800000, receivedDateStr=2009-05-05, revisedDate=-2209017600000, revisedDateStr=1900-01-01, acceptedDate=null, acceptedDateStr=null, onlineDate=1144598400000, onlineDateStr=2006-04-10, pubDate=1144598400000, pubDateStr=2006-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1144598400000, onlineIssueDateStr=2006-04-10, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774073625600, creator=sys-migrate, updateTime=1774073625600, updator=sys-migrate, issue=Issue{id=1242117794456732041, tenantId=1146029695717560320, journalId=1146031591421210625, year='2006', volume='24', issue='0604', pageStart='1', pageEnd='94', issueExtLink='null', onlineDate='null', pubDate='1144598400000', pubDateStr='2006-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774073559629, creator='sys-migrate', updateTime=1774073559629, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=44, endPage=48, ext={EN=ArticleExt(id=1242118073407311878, articleId=1242118071163355767, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Comprehensive Evaluation Study on Therapeusis of the Elder's Diseases Based on Primary Osteoporosis, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=Objective: Taking primary osteoporosis as example, this study was designed to evaluate three therapeusis by multidimensional, especially biology, social psychology and health economics indexes and to provide new pathway and methods for the elder's diseases and the other chronic disease comprehensive evaluation. Methods: The three therapeusis are Vit D+ Ca, estrogen and diphosphonates. The biology indexes are bone mineral density of lumbar (L1-4), total lumbar, thighbone neck and Ward's triangle area. The social psychology indexes are quality of life SF-36 eight dimensionalities and sum total. The health economics indexes are drug cost, examine cost and total cost. Results: ① According to the bone mineral density, the estrogen treatment's effect was significantly worse than before at L-1, ;L-2 and L-Total,VitD+ Ca treatment was significantly worse than before at L-2 and the others were not significant. ② According to the quality of life , the Estrogen treatment effect was significantly better than before at RP and RE, diphosphonates treatment had significant difference at SF and GH,three therapeusis were significantly better than before at SF-36 Total. ③ According to the medical cost, by the end of the first follow-up, there were no significant statistical difference among the three therapeusis and by the end of the second followed-up, the drug cost was significant statistical different and the Vit D+ Ca was cheaper than the others. ④ According to the Data Envelopment Analysis, the data of first follow-up show that DEA of both diphosphonates treatment and estrogen treatment were useful (θ=1), and DEA of Vit D + Ca treatment was not useful (θ<1 ). The bone mineral density of Vit D + Ca treatment could be improved further according to the relaxation variable. The second follow-up showed that DEA of all the three treatments were useful, and all the relaxation variables were zero. Conclusion: ① According to the bone mineral density, the diphosphonates is the best; According to the quality of life, estrogen is the best and according to the cost, the Vit D + Ca is the best. According to the three aspects, in short-term effect,the effect of estrogen and diphosphonates are equivalent, and VitD+ Ca is relative worst; but in long-term effect,the three treatment are equivalent. ② Evaluation of therapeusis may take the different conclusions if clinical practices consider only one aspect. The A index implicates the different result from the B index as well as th, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=MfHvEqsE8W3SNJG1nSrE0w==, pdfFileSize=526484, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242118072908186241, articleId=1242118071163355767, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=基于原发性骨质疏松症的老年疾病不同治疗方案的综合评价研究, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=目的:以原发性骨质疏松症为例,从生物学、社会心理学和卫生经济学等多个维度对3种治疗方案的优劣进行了系统评价,为老年疾病及其它慢性疾病治疗方案的综合评价提供了新的思路和方法。方法:3种治疗方案为VitD+钙剂、雌激素、二膦酸盐,生物学评价指标为腰椎L1-4、Ltotal、股骨颈Neck、Ward’s三角区骨密度;社会心理学评价指标为SF-36的8个维度和总得分;卫生经济学评价指标为药物费用、检查费用和总费用。结果:①骨密度评价,激素组在腰椎L1、腰椎L2、腰椎Total的骨密度治疗前后的差异在统计学上具有显著性意义,VitD+钙剂组在腰椎L2部位的骨密度治疗前后的差异在统计学上具有显著性意义,其它部位的骨密度改变无显著性意义;②生命质量评价,激素组在RP、RE两个维度治疗前后的差异具有显著性意义,二膦酸盐组在SF、GH两个维度的差异有显著性意义,3组方案在SF-36总分的差异均有显著性意义;③医疗费用评价,第一次随访结束时,3组方案在药物费用、检查费用以及总费用上的差异在统计学上均没有显著性意义;在第二次随访结束时,药物费用的差异在统计学上具有显著性意义,VitD+钙剂组低于激素组和二膦...更多酸盐组,其它的在统计学上无显著性意义;④多投入-多产出的DEA综合评价,在第一次随访结束时,二膦酸盐组和激素组的效率值θ=1,即DEA有效;VitD+钙剂组θ<1,即DEA无效,说明在3组方案中,二膦酸盐组和激素组是等效的,VitD+钙剂组相对较差,且根据松弛变量(±S),其可以提高的产出指标是骨密度;在第二次随访结束时,3组方案的效率值θ=1,即均为DEA有效,表明3组方案是等效的。结论:①如果从骨密度角度来判断,二膦酸盐组相对最好;如果从生命质量角度判断,激素组相对最好;如果从医疗费用角度判断,VitD+钙剂组相对最好;如果综合考虑上述3个方面,则在短时间内VitD+钙剂组相对较差,但从长远来看,3组方案是等效的;②如果仅从某一个方面评价医疗方案,则可能出现“盲人摸象”的现象,因此有必要进行多指标综合评价,而本研究采用的数据包络分析是一个比较理想的方法;③根据第一次随访结束时与第二次随访结束时的结果差异,揭示了在医疗方案评价中需要考虑的一个重要变量——时间。, authors=梁渊,沈霖,卢祖洵, 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