Article(id=1242117635148678040, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242117615708082392, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1252857600000, receivedDateStr=2009-09-14, revisedDate=1253548800000, revisedDateStr=2009-09-22, acceptedDate=null, acceptedDateStr=null, onlineDate=1256659200000, onlineDateStr=2009-10-28, pubDate=1256659200000, pubDateStr=2009-10-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1256659200000, onlineIssueDateStr=2009-10-28, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774073521647, creator=sys-migrate, updateTime=1774073521647, updator=sys-migrate, issue=Issue{id=1242117615708082392, tenantId=1146029695717560320, journalId=1146031591421210625, year='2009', volume='27', issue='0920', pageStart='1', pageEnd='140', issueExtLink='null', onlineDate='null', pubDate='1256659200000', pubDateStr='2009-10-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774073517010, creator='sys-migrate', updateTime=1774073517010, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=39, endPage=43, ext={EN=ArticleExt(id=1242117639359759299, articleId=1242117635148678040, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Metabonomic Differences of Plasma Between Abnormal Savda and Unsavda Syndrome Neoplasm Patients, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=The metabonomic differences of plasma between abnormal savda and unsavda syndrome neoplasm are studied in light of the traditional Uighur medicine. Plasma samples were obtained from 80 cases of abnormal savda syndrome neoplasm patients and 160 cases of abnormal unsavda syndrome neoplasm patients. For each sample, the 1H Nuclear Magnetic Resonance (NMR) based metabonomic analysis was performed and the obtained data was analyzed by the Orthogonal Partial Least-Squares Discriminant Analysis (OPLS-DA). The results show that the abnormal savda syndrome neoplasm patients have a lower degree of glucose, Very Low Density Lipoprotein (VLDL), unsaturated lipids, alanine and a higher degree of fatty acid metabolites like acetone, acetoacetate, β-hydrocxy butyrate, isobutyrate; product of glycolysis like lactate, pyruvate; amino acids like leucine, tyrosine, isoleucine, valine, acetylcysteine; another metabolites like myo-inositol,glycoprotein in plasma than the unsavda syndrome neoplasm patients(P<0.05). These findings indicate that the abnormal savda syndrome neoplasm patients have a higher degree of fat mobilization and glycolysis level, their immune function is more seriously damaged and their prognosis may be worse than that of abnormal unsavda syndrome neoplasm patients., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=/OScHByRWCeRgMmsjbvnxQ==, pdfFileSize=575381, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242117637082252214, articleId=1242117635148678040, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=异常黑胆质型与非异常黑胆质型肿瘤患者血浆代谢组学差异分析, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=探讨异常黑胆质型与非异常黑胆质型肿瘤患者血浆差异性代谢成分，描述两种肿瘤患者血浆代谢组学差异。对80例异常黑胆质型肿瘤患者和160例非异常黑胆质型肿瘤患者血浆进行核磁共振氢谱检测，对结果进行正交偏最小二乘判别（OPLS-DA）分析。结果表明，异常黑胆质型肿瘤患者血浆葡萄糖、极低密度脂蛋白、不饱和脂类、丙氨酸含量比非异常黑胆质型肿瘤患者低，差异有统计学意义（P<0.05）。同时，脂肪酸氧化产物乙酰乙酸、β-羟丁酸、丙酮、异丁酸，糖酵解产物乳酸、丙酮酸，以及亮氨酸、酪氨酸、异亮氨酸、缬氨酸、乙酰半胱氨酸、糖蛋白、肌醇等代谢物在血浆中的含量比非异常黑胆质型肿瘤患者高，差异有统计学意义（P<0.05）。由此得出结论：异常黑胆质型肿瘤患者体内的脂肪动员和糖酵解水平比非异常黑胆质型肿瘤患者高，免疫功能的损毁可能比后者严重，预后可能比后者差。, authors=^{巴吐尔·买买提明1,2，哈木拉提·吾甫尔1，豪富华3}, authorsList=巴吐尔·买买提明;哈木拉提·吾甫尔;豪富华, authorCompany=1. 新疆医科大学药学院，乌鲁木齐 8300542. 中南大学药学院，长沙 4100073. 中国科学院武汉物理与数学研究所；波谱与原子分子物理国家重点实验室，武汉 430071, correspAuthors=null, authorNote=null, correspAuthorsNote=哈木拉提·吾甫尔, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=XP3u5DtuIXf6XJ5Ypwl4Ww==, pdfFileSize=575381, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, 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