Article(id=1242117576063520842, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242117531259961825, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1250524800000, receivedDateStr=2009-08-18, revisedDate=1252252800000, revisedDateStr=2009-09-07, acceptedDate=null, acceptedDateStr=null, onlineDate=1255363200000, onlineDateStr=2009-10-13, pubDate=1255363200000, pubDateStr=2009-10-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1255363200000, onlineIssueDateStr=2009-10-13, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774073507558, creator=sys-migrate, updateTime=1774073507558, updator=sys-migrate, issue=Issue{id=1242117531259961825, tenantId=1146029695717560320, journalId=1146031591421210625, year='2009', volume='27', issue='0919', pageStart='1', pageEnd='140', issueExtLink='null', onlineDate='null', pubDate='1255363200000', pubDateStr='2009-10-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774073496878, creator='sys-migrate', updateTime=1774073496878, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=94, endPage=98, ext={EN=ArticleExt(id=1242117579007918796, articleId=1242117576063520842, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Antiproliferative Activity of Individual Herbs of Abnormal Savda Munziq on HL-60 Cells, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=Abnormal Savda Munziq (Patent no. C082130082.8) is a herbal formula composed of ten medicinal herbs, namely Glycyrrhiza uralensis, Ziziphus jujuba, Cordia dichotoma, Anchusa italica, Adiantum capillus-veneris, Euphorbia humifusa, Foeniculum vulgare, Lavandula angustifolia, Melissa officinalis and Alhagi pseudoalhagi. It is used in traditional Uighur medicine for the treatment and prevention of cancer, diabetes and cardiovascular diseases. This paper studies the antiproliferative activity of individual herbs of Abnormal Savda Munziq(except Alhagi pseudoalhagi) on HL-60 cells. Cell viability of HL-60 cells exposed to CH2Cl2 extract and MeOH extract of each herb was determined by the trypan blue exclusion method after 24 h, 48 h and 72 h of incubation (37°C, 5% CO2), respectively. As a result, except for Foeniculum vulgare, CH2Cl2 extracts of all herbs significantly reduce the viability of HL-60 cells (P<0.05); MeOH extracts of only two herbs, namely Glycyrrhiza uralensis and Euphorbia humifusa, significantly reduce the viability of HL-60 cells (P<0.05). The cell viability of cells exposed to CH2Cl2 extract of all herbs was shown to be significantly lower than that of cells exposed to its MeOH extract (P<0.05). The results clearly show that the CH2Cl2 extracts of eight herbs, namely Cordia dichotoma, Euphorbia humifusa, Adiantum capillus-veneris, Glycyrrhiza uralensis, Ziziphus jujuba, Lavandula angustifolia, Anchusa italica, Melissa officinalis and the MeOH extracts of two herbs, namely Glycyrrhiza uralensis and Euphorbia humifusa, have in vitro antiproliferative activity on HL-60 cells. The antiproliferative activity of CH2Cl2 extract of each herb is stronger than that of its MeOH extract., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=XV6K64+eUDNlRxdKmRQijQ==, pdfFileSize=460435, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242117577984512081, articleId=1242117576063520842, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=异常黑胆质成熟剂中各单味药对HL-60细胞增殖的抑制作用, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=异常黑胆质成熟剂是维吾尔医复方制剂，由甘草、红枣、破布木、牛舌草、铁线蕨、地锦草、小茴香、薰衣草、蜜蜂花和刺糖10味药组成，用于治疗由异常黑胆质所导致的肿瘤、糖尿病和心血管疾病等。研究了异常黑胆质成熟剂中各单味药（除刺糖外）对HL-60细胞增殖的抑制作用。HL-60细胞暴露于各单味药两种不同提取物（二氯甲烷和甲醇），于37℃、CO2体积分数为5%的恒温孵箱中培养后24、48、72 h，用台盼蓝染色法检测细胞存活率。结果表明，各单味药的二氯甲烷提取物除小茴香外均显著降低HL-60癌细胞的存活率（P<0.05）。在甲醇提取物中，只有甘草和地锦草两味药的甲醇提取物可显著降低HL-60癌细胞的存活率（P<0.05）。与各单味药甲醇提取物相比，其二氯甲烷提取物均显著降低HL-60癌细胞的存活率（P<0.05）。结果显示，破布木、地锦草、铁线蕨、甘草、红枣、薰衣草、牛舌草和蜜蜂花8味药的二氯甲烷提取物和甘草、地锦草两味药的甲醇提取物均能抑制HL-60癌细胞的体外增殖。各单味药二氯甲烷提取物对HL-60细胞增殖的抑制作用均明显强于其相应的甲醇提取物。, authors=^{木拉提·克扎衣别克1，Brigitte Kopp2，Sonja Prinz2，Ruxandra Popescu2，哈木拉提·吾甫尔1}, authorsList=木拉提·克扎衣别克;Brigitte Kopp;Sonja Prinz;Ruxandra Popescu;哈木拉提·吾甫尔, authorCompany=1. 新疆医科大学维吾尔医药系，乌鲁木齐 8300112. 维也纳大学生药系，维也纳 A-1090，奥地利, correspAuthors=null, authorNote=null, correspAuthorsNote=木拉提·克扎衣别克, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=tz6v0vlmbxJyzDSb3Nw4BA==, pdfFileSize=460435, pdfExtLink=null, richHtmlUrl=null, 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