Article(id=1242117114291618027, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242117113696031283, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1247500800000, receivedDateStr=2009-07-14, revisedDate=-2209017600000, revisedDateStr=1900-01-01, acceptedDate=null, acceptedDateStr=null, onlineDate=1252771200000, onlineDateStr=2009-09-13, pubDate=1252771200000, pubDateStr=2009-09-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1252771200000, onlineIssueDateStr=2009-09-13, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774073397464, creator=sys-migrate, updateTime=1774073397464, updator=sys-migrate, issue=Issue{id=1242117113696031283, tenantId=1146029695717560320, journalId=1146031591421210625, year='2009', volume='27', issue='0917', pageStart='3', pageEnd='140', issueExtLink='null', onlineDate='null', pubDate='1252771200000', pubDateStr='2009-09-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774073397321, creator='sys-migrate', updateTime=1774073397321, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=88, endPage=91, ext={EN=ArticleExt(id=1242117117852586568, articleId=1242117114291618027, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Usage of Cisatracurium Besilate in Adult Anesthesia Induction, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=The clinical effect of different doses of cisatricurium besilate in adults after anesthesia induction is discussed in this paper. Sixty aged 25 to 65 years old ASA class I～II adult patients scheduled for elective surgery were randomized assigned to three groups: C2 (2ED95: cisatricurium 0.1 mg/kg), C3 (3ED95: cisatricurium 0.15 mg/kg), C4 (4ED95: cisatricurium 0.2 mg/kg) or C6 (6ED95: cisatricurium 0.3 mg/kg) and were given 2ED95, 3ED95, 4ED95 or 6ED95 of cisatricurium besilate, respectively. Patients were free of psychiatric, neurologic, neuromuscular, hepatic, renal, pulmonary, and cardiovascular diseases, and without a history of unusual susceptibility to neuromuscular blocking drugs or malignant hyperthermia. Anesthesia was induced by intravenous injection of sufentanil and propofol, after which different doses of cisatricurium were given in 5 s. Tracheal intubation was performed. As soon as the Train-of-Four Stimulations (TOF) arrived at 0, the onset time, clinical duration, recovery time and recovery index were recorded. The results show that tracheal intubation are performed successfully in all four groups. The onset time is shortened and the recovery time is prolonged as the dose of cisatricurium besilate is increased. But the recovery index is similar in all groups. No adverse effects were recorded in all groups. It is concluded that all 4 doses of cisatricurium besylate can produce anesthesia induction and intubation. As doses are increased in 2ED95～6ED95, the onset time is shortened and the recovery time is prolonged while the recovery index is similar for adults., authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=Fan Ting, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=QzczKDc44KETVzW7cq03Wg==, pdfFileSize=726885, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242117117097611841, articleId=1242117114291618027, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=国产苯磺酸顺式阿曲库铵在成人麻醉诱导中的应用, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=观察不同剂量国产苯磺酸顺式阿曲库铵用于成人麻醉诱导的药效学与插管条件。根据美国麻醉医师协会（ASA）分级I～II级，选择60例择期行面肌痉挛纤维血管减压术、年龄在27～65岁的患者，随机均分为C2（2倍ED95组：2倍95%的有效药物剂量）、C3（3倍ED95组）、C4（4倍ED95组）和C6（6倍ED95组）4个组。各组在麻醉诱导后于5 s内单次静脉注入相应剂量的苯磺酸顺式阿曲库铵。采用国产BIOMETER拇内收肌肌张力肌松监测仪测定拇内收肌诱发颤搐反应的变化，观察气管插管条件以及苯磺酸顺式阿曲库铵的药效学。结果显示，4个组均能完成气管插管，C6组插管评分显著低于C2、C3、C4组，而C2、C3和C4组插管评分差异无统计学意义（P>0.05）。4组阻滞起效时间随剂量的增加相应缩短，TOF无反应期、阻滞维持时间、体内作用时间随剂量增加而延长，但各组肌松恢复指数差异无统计学意义（P>0.05）。4组患者均无过敏反应发生。因此得出结论：成年患者，2倍ED95、3倍ED95 、4倍ED95和6倍ED95苯磺酸顺式阿曲库铵均能成功诱导插管，不同剂量苯磺酸顺阿曲库铵随剂量的增加起效时间缩短，肌松作用时间延长，但肌松恢复指数无差异。, authors=范婷,安建雄,林艳君, authorsList=范婷;安建雄;林艳君, authorCompany=清华大学玉泉医院麻醉与疼痛医学科, correspAuthors=null, authorNote=null, correspAuthorsNote=范婷, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=6s4BbvBEx5WYK6Uw9s9D3g==, pdfFileSize=726885, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, 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