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被誉为“减肥神药”的司美格鲁肽（Semaglutide）再次突破了人们的认知边界。长期以来，医学界普遍认为此类药物改善关节炎仅仅是因为“体重减轻降低了关节负重”。然而，中国科学院深圳先进技术研究院童丽萍、陈棣、John Speakman团队联合暨南大学张还添团队发现，司美格鲁肽能直接作用于软骨细胞，通过重塑能量代谢规律来保护关节，且这一过程完全独立于减重效果。2026年2月9日，相关研究成果发表于《Cell Metabolism》。

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（图片来源：骨科医生网）

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