Article(id=1208361640513352549, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1208361635656352181, articleNumber=null, orderNo=25, doi=10.3981/j.issn.1000-7857.2025.01.00025, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1736092800000, receivedDateStr=2025-01-06, revisedDate=1744387200000, revisedDateStr=2025-04-12, acceptedDate=1755446400000, acceptedDateStr=2025-08-18, onlineDate=1766025465371, onlineDateStr=2025-12-18, pubDate=1757692800000, pubDateStr=2025-09-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1762358400000, onlineIssueDateStr=2025-11-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1766025465371, creator=13701087609, updateTime=1774079977208, updator=sys-migrate, issue=Issue{id=1208361635656352181, tenantId=1146029695717560320, journalId=1146031591421210625, year='2025', volume='43', issue='17', pageStart='1', pageEnd='144', issueExtLink='null', onlineDate='null', pubDate='1757692800000', pubDateStr='2025-09-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1766025464214, creator='13701087609', updateTime=1774330860874, updator='13041195026', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1243196994169189037, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1208361635656352181, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1243196994169189038, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1208361635656352181, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=141, endPage=144, ext={EN=ArticleExt(id=1208361640840508274, articleId=1208361640513352549, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=A new dimension of gene regulation——Ambros's and Ruvkun's research experience and implications, columnId=1150494646058185020, journalTitle=Science & Technology Review, columnName=Science and Humanity, runingTitle=null, highlight=null, articleAbstract=

The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun "for the discovery of miRNA and its role in post−transcriptional gene regulation". The article reviews the discovery journey of miRNA and its role of regulation, proposing that always pursuing one's own interests and constantly delving deeper, not afraid to pause temporarily, learning to simplify complex research are all crucial factor for supporting researchers to climb the peak of scientific research.

, authors=null, authorsList=Biao CHEN, Yuhao JIAO, Mengru SHEN, Anting PENG, Yuewei ZHU, Yangmenglin RUI, Chunxiu WANG, Xinying HAO, authorCompany=null, correspAuthors=Xinying HAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=All rights reserved. Unauthorized reproduction is prohibited., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1208361642493064069, articleId=1208361640513352549, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=微小RNA，大时代：安布罗斯与鲁夫昆的科研征途及启示, columnId=1150494646196597053, journalTitle=科技导报, columnName=科技人文, runingTitle=null, highlight=null, articleAbstract=

维克托·安布罗斯和加里·鲁夫昆因发现“miRNA及其在转录后基因调控中的作用”而获2024年诺贝尔生理学或医学奖。梳理了2人发现miRNA及其调控作用的科研之路，总结出追寻兴趣深入、不惧暂时驻足、学会化繁为简3点对于科研人员勇攀科研高峰至关重要的影响因素。

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陈彪，副教授，研究方向为科技史、科技考古，电子信箱：chenbiao@ustc.edu.cn

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