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As a special group of patients, the senile depression patients are often accompanied with physical diseases. This study evaluated the antidepressant efficacy and prognostic quality of life (QoL) of cognitive-behavioral therapy (CBT) combined with low-dose Duloxetine in elderly patients of depression with comorbidities. The indicators are the clinical onset time of the antidepressant based on the Hamilton Rating Scale for Depression (HAMD), the antidepressant efficacy based on the Montgomery-Asberg Depression Rating Scale (MADRS), and the Croog QoL. The results show that the clinical effective rate (77.4%) of the treatment group at 2 weeks was significantly higher than that of the control group (60.8%) (P=0.027). The depression level of the treatment group at 1 year was lower than that of the control group (P=0.005), and the QoL of the treatment group at 1 and 1.5 years was significantly higher than that of the control group (P<0.001) (P=0.035). It suggests that the CBT combined with antidepressant can shorten the onset time, improve its efficacy and the overall function and prognostic QoL of the patients, helping them to return to social activities., authors=LI Ping1,2 , SUN Zhigang1,2 , XU Manhua1 , HE Lanying1 , DU Yimin1 , WANG Lifeng1 , ZHANG Pei1 , SONG Lihua1 , authorsList=LI Ping, SUN Zhigang, XU Manhua, HE Lanying, DU Yimin, WANG Lifeng, ZHANG Pei, SONG Lihua, authorCompany=1. Shijiazhuang Eighth Hospital, Shijiazhuang 050081, China; 2. Shijiazhuang Mental Health Center, Shijiazhuang 050081, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242141970164949026, articleId=1242141967937773588, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=认知行为疗法对合并躯体疾病的老年抑郁症患者的疗效与优势, columnId=1242141965182116849, journalTitle=科技导报, columnName=专题:抗衰老与老年健康, runingTitle=null, highlight=null, articleAbstract=随着人口老龄化的加速,老年抑郁症(DEP)的发病率逐年增加,严重威胁着老年人的身心健康。老年患者是DEP的特殊群体,常合并躯体疾病。以合并躯体疾病的老年DEP患者为研究对象,评价认知行为疗法(CBT)联合低剂量度洛西汀的抗抑郁疗效和预后整体生活质量(QoL),指标包括基于汉密尔顿抑郁量表(HAMD)的临床起效时间、基于蒙哥马利抑郁评定量表(MADRS)的抗抑郁疗效、Croog QoL量表。结果显示,研究组治疗2周时的临床有效率(77.4%)显著高于药物对照组(60.8%)(P =0.027),研究组1 a时的抑郁程度低于对照组(P= 0.005),研究组1、1.5 a时的QoL显著高于对照组(P <0.001)(P =0.035)。说明CBT联合治疗合并躯体疾病的老年DEP具有缩短起效时间、提高抗抑郁疗效,改善患者整体功能,提高预后QoL的优势,可促进患者回归社会生活。, authors=李平1,2 , 孙志刚1,2 , 徐曼华1 , 何兰英1 , 杜义敏1 , 王立峰1 , 张培1 , 宋丽华1 , authorsList=李平, 孙志刚, 徐曼华, 何兰英, 杜义敏, 王立峰, 张培, 宋丽华, authorCompany=1. 石家庄市第八医院, 石家庄 050081; 2. 石家庄市精神心理疾病临床医学研究中心, 石家庄 050081, correspAuthors=null, authorNote=李平,副主任医师,研究方向为情感障碍识别干预、精神障碍诊疗,电子信箱:lipingyucca@163.com;孙志刚(通信作者),主任医师,研究方向为精神分裂症、老年性精神障碍临床研究,心理危机干预,电子信箱:sunzhigang0913@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=w2SrCswlxygagXz5w+dyug==, pdfFileSize=711705, pdfExtLink=null, richHtmlUrl=null, 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科技导报
| 专题:抗衰老与老年健康 2024, 42(22): 49-55
认知行为疗法对合并躯体疾病的老年抑郁症患者的疗效与优势
全屏
李平1,2 , 孙志刚1,2 , 徐曼华1 , 何兰英1 , 杜义敏1 , 王立峰1 , 张培1 , 宋丽华1
作者信息
1. 石家庄市第八医院, 石家庄 050081; 2. 石家庄市精神心理疾病临床医学研究中心, 石家庄 050081
Efficacy and advantages of cognitive-behavioral therapy in elderly depression patients complicated with physical diseases
Affiliations
出版时间: 2024-11-28
doi: 10.3981/j.issn.1000-7857.2024.06.00628
文章导航
随着人口老龄化的加速,老年抑郁症(DEP)的发病率逐年增加,严重威胁着老年人的身心健康。老年患者是DEP的特殊群体,常合并躯体疾病。以合并躯体疾病的老年DEP患者为研究对象,评价认知行为疗法(CBT)联合低剂量度洛西汀的抗抑郁疗效和预后整体生活质量(QoL),指标包括基于汉密尔顿抑郁量表(HAMD)的临床起效时间、基于蒙哥马利抑郁评定量表(MADRS)的抗抑郁疗效、Croog QoL量表。结果显示,研究组治疗2周时的临床有效率(77.4%)显著高于药物对照组(60.8%)(P =0.027),研究组1 a时的抑郁程度低于对照组(P= 0.005),研究组1、1.5 a时的QoL显著高于对照组(P <0.001)(P =0.035)。说明CBT联合治疗合并躯体疾病的老年DEP具有缩短起效时间、提高抗抑郁疗效,改善患者整体功能,提高预后QoL的优势,可促进患者回归社会生活。
老年抑郁症
/
躯体疾病
/
认知行为疗法
/
预后生活质量
/
临床起效时间
/
5-羟色胺及去甲肾上腺素再摄取抑制剂
With the acceleration of population aging, the incidence of senile depression is increasing year by year, which seriously threatens the physical and mental health of the elder adults. As a special group of patients, the senile depression patients are often accompanied with physical diseases. This study evaluated the antidepressant efficacy and prognostic quality of life (QoL) of cognitive-behavioral therapy (CBT) combined with low-dose Duloxetine in elderly patients of depression with comorbidities. The indicators are the clinical onset time of the antidepressant based on the Hamilton Rating Scale for Depression (HAMD), the antidepressant efficacy based on the Montgomery-Asberg Depression Rating Scale (MADRS), and the Croog QoL. The results show that the clinical effective rate (77.4%) of the treatment group at 2 weeks was significantly higher than that of the control group (60.8%) (P=0.027). The depression level of the treatment group at 1 year was lower than that of the control group (P=0.005), and the QoL of the treatment group at 1 and 1.5 years was significantly higher than that of the control group (P<0.001) (P=0.035). It suggests that the CBT combined with antidepressant can shorten the onset time, improve its efficacy and the overall function and prognostic QoL of the patients, helping them to return to social activities.
senile depression
/
physical diseases
/
cognitive-behavioral therapy
/
prognostic quality of life
/
clinical efficacy times
/
selectiveserotonin-norepinephrine reuptake inhibitor
李平, 孙志刚, 徐曼华, 何兰英, 杜义敏, 王立峰, 张培, 宋丽华.
认知行为疗法对合并躯体疾病的老年抑郁症患者的疗效与优势.
科技导报,
2024
, 42
(22)
: 49
-55
.
DOI: 10.3981/j.issn.1000-7857.2024.06.00628
LI Ping, SUN Zhigang, XU Manhua, HE Lanying, DU Yimin, WANG Lifeng, ZHANG Pei, SONG Lihua.
Efficacy and advantages of cognitive-behavioral therapy in elderly depression patients complicated with physical diseases[J].
Science & Technology Review ,
2024
, 42
(22)
: 49
-55
.
DOI: 10.3981/j.issn.1000-7857.2024.06.00628
2024年第42卷第22期
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文章信息
doi: 10.3981/j.issn.1000-7857.2024.06.00628
接收时间:2024-03-05
首发时间:2024-12-26
出版时间:2024-11-28
收稿日期:2024-03-05
修回日期:2024-07-20
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2024.06.00628
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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