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SPARC计划II期:聚焦迷走神经
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科技导报 | 综述 2023,41(6): 121-126
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科技导报 | 综述 2023, 41(6): 121-126
SPARC计划II期:聚焦迷走神经
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辛陈1,荣培晶1*,李少源1,王瑜1,陈瑜1,陈建德2,魏玮3,丛斌4
作者信息
    1. 中国中医科学院针灸研究所,北京 100700
    2. 密歇根大学胃肠病和肝病学部,安娜堡 48109
    3. 中国中医科学院望京医院,北京 100102
    4. 河北医科大学法医学系,石家庄 050017

通讯作者:

荣培晶(通信作者),研究员,研究方向为针灸效应机制,电子信箱:drrongpj@163.com
SPARC Phase II: Focusing on the vagus nerve
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出版时间: 2023-03-28 doi: 10.3981/j.issn.1000-7857.2023.06.012
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美国国立卫生院(NIH)于 2016 年启动的“刺激外周神经缓解疾病症状”(SPARC)计划,已于2022年开展II期研究。与I期关注整体外周神经系统相比,SPARC计划II期的最大特点在于专注研究迷走神经。通过梳理迷走神经刺激(VNS)临床应用现状、迷走神经与炎症反射、迷走神经与内感受系统等前沿进展,探索了SPARC计划II期聚焦迷走神经的原因,提出了迷走神经感觉神经元的识别和研究范式,对揭示针灸作用于体表-脏腑的机制原理具有启发和借鉴意义。
SPARC  /  外周神经  /  迷走神经  /  生物电子药  /  针灸
"Stimulating Peripheral Activity to Relieve Conditions" program (SPARC), which was initiated by the National Institutes of Health (NIH) in 2016, has been proceed to the next stage in 2022. Compared with the first stage, which focused on the peripheral nervous system as a whole, the most important feature of the SPARC Phase II is its focus on the vagus nerve. This paper explores the reasons for the focus of Phase II by sorting out the current status of the clinical application of vagus nerve stimulation (VNS), the vagus nerve and inflammatory reflexes, and the vagus nerve and the introception system. More importantly, the identification and study paradigm of vagal sensory neurons is enlightening and informative to reveal the mechanism of acupuncture acting on the body's surface and visceral organs.
SPARC  /  peripheral nerve  /  vagus nerve  /  bioelectronic medicines  /  acupuncture
辛陈,荣培晶,李少源,王瑜,陈瑜,陈建德,魏玮,丛斌. SPARC计划II期:聚焦迷走神经. 科技导报, 2023 , 41 (6) : 121 -126 . DOI: 10.3981/j.issn.1000-7857.2023.06.012
XIN Chen, RONG Peijing, LI Shaoyuan, WANG Yu, CHEN Yu, CHEN Jiande, WEI Wei, CONG Bin. SPARC Phase II: Focusing on the vagus nerve[J]. Science & Technology Review, 2023 , 41 (6) : 121 -126 . DOI: 10.3981/j.issn.1000-7857.2023.06.012
2023年第41卷第6期
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doi: 10.3981/j.issn.1000-7857.2023.06.012
  • 接收时间:2022-05-28
  • 首发时间:2023-04-23
  • 出版时间:2023-03-28
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  • 收稿日期:2022-05-28
  • 修回日期:2022-12-02
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荣培晶(通信作者),研究员,研究方向为针灸效应机制,电子信箱:drrongpj@163.com
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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