Article(id=1242139443621081637, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242139419398975988, articleNumber=null, orderNo=19, doi=10.3981/j.issn.1000-7857.2021.18.013, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1558454400000, receivedDateStr=2019-05-22, revisedDate=1570204800000, revisedDateStr=2019-10-05, acceptedDate=null, acceptedDateStr=null, onlineDate=1633747989647, onlineDateStr=2021-10-09, pubDate=1632758400000, pubDateStr=2021-09-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1633747989647, onlineIssueDateStr=2021-10-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774078721190, creator=sys-migrate, updateTime=1774078721190, updator=sys-migrate, issue=Issue{id=1242139419398975988, tenantId=1146029695717560320, journalId=1146031591421210625, year='2021', volume='39', issue='18', pageStart='0', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1632758400000', pubDateStr='2021-09-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774078715416, creator='sys-migrate', updateTime=1774078715416, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=94, endPage=100, ext={EN=ArticleExt(id=1242139446880051400, articleId=1242139443621081637, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=The hypoglycemic effects of jackfruit oligopeptides in db/db diabetic mice, columnId=1150494644690366681, journalTitle=Science & Technology Review, columnName=Papers, runingTitle=null, highlight=null, articleAbstract=To study the hypoglycemic effects of jackfruit oligopeptides in db/db diabetic mice, 48 db/db diabetic mice are randomly divided into six groups (with 8 mice in each group):three jackfruit oligopeptides groups (with 0.2 g/kg·bw, 0.4 g/kg·bw and 0.8 g/kg·bw JOPs, respectively, by intragastric administration), a diabetic model group, a metformin control group (with 0.2 g/kg·bw metformin hydrochloride enteric-coated tablets aqueous solution by intragastric administration) and a whey protein control group (with 0.4 g/kg·bw whey protein aqueous solution by intragastric administration), while 10 db/m mice are used as the blank control for non-diabetic mice. The fasting glucose, the OGTT-AUC, the liver glycogen and the muscle glycogen are measured during the intervention. It is shown that the JOPs could decrease the fasting blood glucose and the OGTT-AUC in the diabetic mice (P<0.05), especially in the 0.4g/kg·bw-dose group. The long-term jackfruit oligopeptides intervention can effectively reduce the blood glucose level and improve the glucose tolerance of diabetic mice., authors=LIU Xinran, KANG Jiawei, WANG Tianxing, HAO Yuntao, ZHU Na, LIU Rui, HU Jiani, MAO Ruixue, LI Yong, authorsList=LIU Xinran, KANG Jiawei, WANG Tianxing, HAO Yuntao, ZHU Na, LIU Rui, HU Jiani, MAO Ruixue, LI Yong, authorCompany=Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=z9bgCme7Is+2r/hboMBf8A==, pdfFileSize=1369000, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242139446016029242, articleId=1242139443621081637, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=菠萝蜜低聚肽对db/db糖尿病小鼠血糖的影响, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=关于菠萝蜜的研究显示其具有一定的降血糖作用，但尚未有关于菠萝蜜低聚肽（Jack-fruit oligopeptides，JOPs）降血糖的研究。通过菠萝蜜低聚肽干预，研究其对db/db糖尿病模型小鼠血糖的影响作用。将db/db糖尿病小鼠模型，随机分为3个菠萝蜜低聚肽组（0.2 g/kg·bw、0.4 g/kg·bw、0.8 g/kg·bw）以及糖尿病模型对照组、二甲双胍对照组、乳清蛋白对照组；并选用db/m小鼠作为非糖尿病小鼠空白对照。经过为期6周的干预，检测小鼠空腹血糖、糖耐量实验血糖曲线下面积及组织中糖原含量。结果表明，菠萝蜜低聚肽可显著降低db/db糖尿病小鼠空腹血糖水平，显著降低糖耐量实验血糖曲线下面积（P<0.05），其效果以0.4 g/kg·bw剂量组最为显著。菠萝蜜低聚肽干预可有效降低糖尿病小鼠的血糖水平，改善糖耐量，具有辅助降血糖作用。, authors=刘欣然, 康家伟, 王天星, 郝云涛, 珠娜, 刘睿, 胡佳妮, 毛瑞雪, 李勇, authorsList=刘欣然, 康家伟, 王天星, 郝云涛, 珠娜, 刘睿, 胡佳妮, 毛瑞雪, 李勇, authorCompany=北京大学公共卫生学院营养与食品卫生学系, 北京 100191, correspAuthors=null, authorNote=刘欣然,博士研究生,研究方向为营养与疾病,电子信箱:liuhappy07@163.com, correspAuthorsNote=李勇(通信作者),教授,研究方向为肽营养学;营养与疾病,电子信箱:liyongbmu@163.com, copyrightStatement=null, 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