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The iron supplementation therapy was reported to improve the symptoms of sleep movements in some children., authors=SUN Yifan, LI Taomei, ZHANG Haipeng, SHI Yuan, TANG Xiangdong, authorsList=SUN Yifan, LI Taomei, ZHANG Haipeng, SHI Yuan, TANG Xiangdong, authorCompany=Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=TyV+mhzKXPBwU9Hlq0riUA==, pdfFileSize=695940, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242139438638244008, articleId=1242139436939555344, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=铁缺乏相关儿童睡眠障碍研究进展, 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科技导报 | 专题:儿童青少年心理健康 2021,39(18): 57-64
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科技导报 |专题:儿童青少年心理健康 2021 , 39 (18) : 57 -64
铁缺乏相关儿童睡眠障碍研究进展
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孙一凡, 李桃美, 张海鹏, 时媛, 唐向东
作者信息
    四川大学华西医院睡眠医学中心, 成都 610041
通讯作者:
唐向东(通信作者),教授,研究方向为睡眠医学,电子信箱:2372564613@qq.com
作者简介:
孙一凡,硕士,研究方向为睡眠医学,电子信箱:1014585663@qq.com
Review of studies of iron deficiency-related sleep disorders in children
  • SUN Yifan, LI Taomei, ZHANG Haipeng, SHI Yuan, TANG Xiangdong
  • Affiliations
      Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China
    出版时间: 2021-09-28 doi: 10.3981/j.issn.1000-7857.2021.18.008
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    铁缺乏是儿童最常见的微量营养素缺乏症。中国缺铁儿童数量众多,尤其婴幼儿是铁缺乏的高发人群;睡眠是机体发育、修复、调整的重要环节,良好的睡眠对发育中的个体尤其重要。近年来,研究发现铁缺乏可能与几类常见的儿童睡眠障碍有关。从临床特点、病理机制和补铁治疗等方面,回顾了国内外铁缺乏相关儿童睡眠障碍的研究前沿成果。研究结果表明,铁缺乏可能通过引起神经递质紊乱,影响神经髓鞘和树突的形成等途径,导致缺铁儿童睡眠中异常活动增多,补铁治疗被发现可改善部分患儿的睡眠运动症状。
    铁缺乏  /  缺铁性贫血  /  儿童睡眠障碍
    The iron deficiency is the most common micro-nutrient deficiency in children, with a large number of children falling victims in China, especially infants, which are at a very high risk. The sleep plays an important part in the body's development, repair and adjustment, and is particularly important in the developing stage. It is revealed by increasing number of studies that the iron deficiency is probably associated with several common sleep disorders in children. This paper reviews the cutting-edge studies of iron deficiency-related sleep disorders in children, including the clinical characteristics, the possible pathological mechanism and the iron supplement therapy. The iron deficiency may lead to increased abnormal activities during sleep in children by causing disorders of neurotransmitters, altering the processes of the myelination and the formation of dendrites. The iron supplementation therapy was reported to improve the symptoms of sleep movements in some children.
    iron deficiency  /  iron deficiency anemia  /  sleep disorders in children
    孙一凡, 李桃美, 张海鹏, 时媛, 唐向东. 铁缺乏相关儿童睡眠障碍研究进展. 科技导报, 2021 , 39 (18) : 57 -64 . DOI: 10.3981/j.issn.1000-7857.2021.18.008
    SUN Yifan, LI Taomei, ZHANG Haipeng, SHI Yuan, TANG Xiangdong. Review of studies of iron deficiency-related sleep disorders in children[J]. Science & Technology Review, 2021 , 39 (18) : 57 -64 . DOI: 10.3981/j.issn.1000-7857.2021.18.008

      国家自然科学基金项目(81530002)

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    doi: 10.3981/j.issn.1000-7857.2021.18.008
    • 接收时间:2020-09-27
    • 首发时间:2021-10-09
    • 出版时间:2021-09-28
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    • 收稿日期:2020-09-27
    • 修回日期:2021-02-18
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    唐向东(通信作者),教授,研究方向为睡眠医学,电子信箱:2372564613@qq.com
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    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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