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The PDWs, ALBs and MPVs of the two groups were observed and the clinical values of predicting thyroid cancer were evaluated. Results show that MPV and ALB of the study group are lower and PDW is higher than those of the control group, and the differences are statistically significant (P<0.05). PDW, MPV,ALB in the diagnosis of thyroid cancer AUC are not statistically significant (P > 0.05). The specificity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone, and the sensitivity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone. Therefore, PDW, MPV and ALB are of moderate clinical value in the differential diagnosis of benign and malignant thyroid nodules. Different combination of the three indexes is helpful to the diagnosis or exclusion of thyroid cancer., authors=LI Juan, ZHANG Xuehui, FENG Shuangshuang, SHEN Jinfu, XIE Shuyong, NIU Min, authorsList=LI Juan, ZHANG Xuehui, FENG Shuangshuang, SHEN Jinfu, XIE Shuyong, NIU Min, authorCompany=Fuyang People's Hospital, Fuyang 236000, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=xBfRRDAEGpcBMaQLsTGjEw==, pdfFileSize=746060, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242139058789494888, articleId=1242139056440684633, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=血小板分布宽度和血清白蛋白水平鉴别甲状腺肿瘤性质的临床进展, columnId=1242139053236232903, journalTitle=科技导报, columnName=专题:肿瘤标志物, runingTitle=null, highlight=null, articleAbstract=为观察和分析血小板分布宽度(PDW)、平均血小板体积(MPV)和血清白蛋白(Alb)水平对甲状腺癌与甲状腺良性结节的鉴别价值,选择2018年12月至2020年9月在安徽省阜阳市人民医院确诊的237例甲状腺癌患者作为研究组,并抽取在该院就诊的237例良性甲状腺结节患者作为对照组。观察2组患者PDW、MPV和Alb水平及预测甲状腺癌的临床价值。结果表明:研究组MPV、Alb均低于对照组,PDW高于对照组,差异均有统计学意义(P<0.05);PDW、MPV、Alb诊断甲状腺癌曲线下面积(AUC)相比较差异均无统计学意义(P>0.05)。PDW、MPV、Alb均阳性为检测指标特异性高于PDW、MPV、Alb单纯诊断的特异性;PDW、MPV、Alb之一阳性为检查指标灵敏度高于PDW、MPV、Alb单独诊断的灵敏度。因此,PDW、MPV和Alb对甲状腺良恶性结节的鉴别具有中等临床价值,3者不同联合方式有助于甲状腺癌确诊或排除。, authors=李娟, 张学辉, 冯双双, 申金付, 谢树永, 牛敏, authorsList=李娟, 张学辉, 冯双双, 申金付, 谢树永, 牛敏, authorCompany=安徽省阜阳市人民医院, 阜阳 236000, correspAuthors=null, authorNote=李娟,副主任医师,研究方向为糖尿病、下丘脑、垂体、矮小、性早熟,电子信箱:563083501@qq.com, correspAuthorsNote=牛敏(通信作者),主任医师,研究方向为糖尿病、甲状腺疾、垂体、矮小症等,电子信箱:niumin661588@163.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=L+rFhjL6bBHfikjgqBop/Q==, pdfFileSize=746060, 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血小板分布宽度和血清白蛋白水平鉴别甲状腺肿瘤性质的临床进展
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科技导报 | 专题:肿瘤标志物 2021,39(7): 79-84
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科技导报 | 专题:肿瘤标志物 2021, 39(7): 79-84
血小板分布宽度和血清白蛋白水平鉴别甲状腺肿瘤性质的临床进展
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李娟, 张学辉, 冯双双, 申金付, 谢树永, 牛敏
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    安徽省阜阳市人民医院, 阜阳 236000

通讯作者:

牛敏(通信作者),主任医师,研究方向为糖尿病、甲状腺疾、垂体、矮小症等,电子信箱:niumin661588@163.com
Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules
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出版时间: 2021-04-13 doi: 10.3981/j.issn.1000-7857.2021.07.008
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为观察和分析血小板分布宽度(PDW)、平均血小板体积(MPV)和血清白蛋白(Alb)水平对甲状腺癌与甲状腺良性结节的鉴别价值,选择2018年12月至2020年9月在安徽省阜阳市人民医院确诊的237例甲状腺癌患者作为研究组,并抽取在该院就诊的237例良性甲状腺结节患者作为对照组。观察2组患者PDW、MPV和Alb水平及预测甲状腺癌的临床价值。结果表明:研究组MPV、Alb均低于对照组,PDW高于对照组,差异均有统计学意义(P<0.05);PDW、MPV、Alb诊断甲状腺癌曲线下面积(AUC)相比较差异均无统计学意义(P>0.05)。PDW、MPV、Alb均阳性为检测指标特异性高于PDW、MPV、Alb单纯诊断的特异性;PDW、MPV、Alb之一阳性为检查指标灵敏度高于PDW、MPV、Alb单独诊断的灵敏度。因此,PDW、MPV和Alb对甲状腺良恶性结节的鉴别具有中等临床价值,3者不同联合方式有助于甲状腺癌确诊或排除。
甲状腺癌  /  甲状腺结节  /  血小板分布宽度  /  白蛋白  /  血小板平均体积
In order to analyze the differential values of platelet distribution width (PDW), mean platelet volumes (MPVs), and serum albumin (ALB) levels in thyroid cancer and benign thyroid nodules, 237 patients with thyroid cancer diagnosed in the hospital from Jan. 2016 to Sept. 2020 were selected as the study group, and 237 patients with benign thyroid nodules were selected as the control group. The PDWs, ALBs and MPVs of the two groups were observed and the clinical values of predicting thyroid cancer were evaluated. Results show that MPV and ALB of the study group are lower and PDW is higher than those of the control group, and the differences are statistically significant (P<0.05). PDW, MPV,ALB in the diagnosis of thyroid cancer AUC are not statistically significant (P > 0.05). The specificity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone, and the sensitivity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone. Therefore, PDW, MPV and ALB are of moderate clinical value in the differential diagnosis of benign and malignant thyroid nodules. Different combination of the three indexes is helpful to the diagnosis or exclusion of thyroid cancer.
thyroid cancer  /  thyroid nodules  /  platelet distribution width  /  albumin  /  mean platelet volum
李娟, 张学辉, 冯双双, 申金付, 谢树永, 牛敏. 血小板分布宽度和血清白蛋白水平鉴别甲状腺肿瘤性质的临床进展. 科技导报, 2021 , 39 (7) : 79 -84 . DOI: 10.3981/j.issn.1000-7857.2021.07.008
LI Juan, ZHANG Xuehui, FENG Shuangshuang, SHEN Jinfu, XIE Shuyong, NIU Min. Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules[J]. Science & Technology Review, 2021 , 39 (7) : 79 -84 . DOI: 10.3981/j.issn.1000-7857.2021.07.008
2021年第39卷第7期
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doi: 10.3981/j.issn.1000-7857.2021.07.008
  • 接收时间:2020-10-04
  • 首发时间:2021-05-13
  • 出版时间:2021-04-13
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  • 收稿日期:2020-10-04
  • 修回日期:2020-12-11
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牛敏(通信作者),主任医师,研究方向为糖尿病、甲状腺疾、垂体、矮小症等,电子信箱:niumin661588@163.com
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Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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