Article(id=1242139047364207265, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242139037352403578, articleNumber=null, orderNo=9, doi=10.3981/j.issn.1000-7857.2021.07.003, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1594569600000, receivedDateStr=2020-07-13, revisedDate=1608652800000, revisedDateStr=2020-12-23, acceptedDate=null, acceptedDateStr=null, onlineDate=1620895401337, onlineDateStr=2021-05-13, pubDate=1618243200000, pubDateStr=2021-04-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1620895401337, onlineIssueDateStr=2021-05-13, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774078626715, creator=sys-migrate, updateTime=1774078626715, updator=sys-migrate, issue=Issue{id=1242139037352403578, tenantId=1146029695717560320, journalId=1146031591421210625, year='2021', volume='39', issue='7', pageStart='1', pageEnd='124', issueExtLink='null', onlineDate='null', pubDate='1618243200000', pubDateStr='2021-04-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774078624329, creator='sys-migrate', updateTime=1774078624329, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=28, endPage=37, ext={EN=ArticleExt(id=1242139054247060176, articleId=1242139047364207265, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Advances in tumor markers, columnId=1242139054154785486, journalTitle=Science & Technology Review, columnName=Exclusive: Tumor Markers, runingTitle=null, highlight=null, articleAbstract=With the development of precision medicine, tumor markers have been paid more and more attention by researchers, and their understanding has gradually made a breakthrough. The research content of tumor markers has been gradually expanded to tumor markers based on tumor genome and chromosomal variations, liquid biopsy, epigenetics and metabolomics; moreover, tumor marker-related detection technologies have developed rapidly, including liquid biopsy, high-throughput gene sequencing, single-cell sequencing and other new technologies; furthermore, with the continuous development of these new high-technologies, tumor marker detection has achieved a breakthrough from single detection to multi-factor combined detection; finally, in clinical practice, tumor marker detection has played an important role in early tumor screening and diagnosis, guiding tumor treatment and predicting efficacy as well as predicting tumor recurrence, metastasis and prognosis, which is of great significance to improve the quality of cancer diagnosis and treatment, and fully realize precision medicine., authors=BAI Rilan, LIANG Tingting, CUI Jiuwei, authorsList=BAI Rilan, LIANG Tingting, CUI Jiuwei, authorCompany=Cancer Center, The First Hospital of Jilin University, Changchun 130021, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=5mPsxwfw5d8sO1FXfTTIwg==, pdfFileSize=646944, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242139053315924680, articleId=1242139047364207265, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=肿瘤标志物研究进展, columnId=1242139053236232903, journalTitle=科技导报, columnName=专题：肿瘤标志物, runingTitle=null, highlight=null, articleAbstract=随着精准医疗的发展，肿瘤标志物越来越得到关注。综述了近期肿瘤标志物的突破性进展：肿瘤标志物研究内容逐步扩展，涉及基于肿瘤基因组和染色体变异、液体活检、表观遗传学和代谢组学等多方面的肿瘤标志物；肿瘤标志物相关检测技术飞速发展，包括液体活检、高通量基因测序、单细胞精准检测及其他新型技术等；并且随着这些新型高科技的不断发展，实现了从单一检测到多因素联合检测的突破；在临床实践中，肿瘤标志物检测已在肿瘤早期筛查和诊断、指导肿瘤治疗并预测疗效、预测肿瘤复发转移和预后方面发挥重要作用，对于提高肿瘤诊治质量、充分实现精准医学具有重要意义。, authors=白日兰, 梁婷婷, 崔久嵬, authorsList=白日兰, 梁婷婷, 崔久嵬, authorCompany=吉林大学第一医院肿瘤中心, 长春 130021, correspAuthors=null, authorNote=白日兰,硕士研究生,研究方向为肿瘤综合治疗,电子信箱:bairilan@foxmail.com, correspAuthorsNote=崔久嵬(通信作者),教授,研究方向为肿瘤综合诊治的基础和临床,电子信箱:cuijw@jlu.edu.cn, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=1NhlYFIGYK0b4ccwszb+OQ==, pdfFileSize=646944, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=吉林省发展和改革委员会省级产业创新专项资金项目（2017C022）；吉林省科技厅重点实验室建设项目（20170622011JC）)}, 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