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科技导报 |综述文章 2014 , 32 (30) : 80 -84
远红外在生物医学临床上的应用及其作用机制
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王阳1, 水珊珊2, 王霞1
作者信息
    1. 合肥工业大学医学工程学院, 合肥230009;
    2. 合肥工业大学生物与食品工程学院, 合肥230009
通讯作者:
王霞(通信作者),讲师,研究方向为基于时间生物学的药物和疾病研究,电子信箱:wangx@hfut.edu.cn
作者简介:
王阳,硕士研究生,研究方向为生物医学仪器,电子信箱:331524718@qq.com;
Molecular Mechanism of Far- infrared Therapy and Its Applications in Biomedicine
  • WANG Yang1, SHUI Shanshan2, WANG Xia1
  • Affiliations
      1. School of Medical Engineering, Hefei University of Technology, Hefei 230009, China;
      2. School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, China
    出版时间: 2014-10-28 doi: 10.3981/j.issn.1000-7857.2014.30.014
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    远红外是一种具有强热作用的放射线.作为物理治疗的一种,远红外用于辅助治疗心血管疾病、糖尿病、慢性肾病等多种疾病,表现出良好的临床效果,但是其作用的分子机制尚不清楚.本文从分子信号通路视角,分析远红外与细胞周期、细胞自身保护、第二信使和后转录调控因子等的关系,提出远红外治疗诸多疾病的可能的分子机制,并总结了近年来远红外在生物医学临床中的应用.
    物理治疗  /  远红外  /  分子信号通路
    Physical therapy is an integrating domain of medicine resorts to physical modalities for the work-up, diagnosis, and treatment of disorders and defects. As a representative physical therapy, far-infrared radiation (FIR), an invisible electromagnetic wave with wavelength ranges 3-1000 μm, has been an adjuvant treatment for various diseases with good clinical effects, including cardiovascular disease, diabetes mellitus, chronic kidney disease; however, the molecular mechanism through which FIR works remains elusive. In the present study, by systematic literature review and text mining, we analyzed the effects of FIR on signaling transduction networks including cell cycle, cellular self-defense, second messages and post-transcriptional regulators. The results showed that the possible mechanisms of FIR therapy were closely associated with the inhibition of growth, invasion and metastasis of cancer cells, increased nitric oxide production and modulation of the expression profiles of some circulating miRNAs and heat shock proteins, and through which, it may be a beneficial compliment to some chronic diseases without any side effects. Finally, we summarized the application of FIR therapy in the field of biomedicine.
    physical therapy  /  far-infrared radiation  /  molecular signaling transduction
    王阳, 水珊珊, 王霞. 远红外在生物医学临床上的应用及其作用机制. 科技导报, 2014 , 32 (30) : 80 -84 . DOI: 10.3981/j.issn.1000-7857.2014.30.014
    WANG Yang, SHUI Shanshan, WANG Xia. Molecular Mechanism of Far- infrared Therapy and Its Applications in Biomedicine[J]. Science & Technology Review, 2014 , 32 (30) : 80 -84 . DOI: 10.3981/j.issn.1000-7857.2014.30.014

      校企联合技术研发研目(13-240)

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    doi: 10.3981/j.issn.1000-7857.2014.30.014
    • 接收时间:2014-08-05
    • 首发时间:2014-11-14
    • 出版时间:2014-10-28
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    • 收稿日期:2014-08-05
    • 修回日期:2014-09-02
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    王霞(通信作者),讲师,研究方向为基于时间生物学的药物和疾病研究,电子信箱:wangx@hfut.edu.cn
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    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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