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2. Faculty of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi 830011, China, fund=null, authors=MAIMAITIAILI Abudunaibi1 , ABUDUREHEMAN Mulati1 , SHABITI Aisikaer1 , AIBIBULA Aili1 , UPUR Halmurat2 , authorsList=MAIMAITIAILI Abudunaibi, ABUDUREHEMAN Mulati, SHABITI Aisikaer, AIBIBULA Aili, UPUR Halmurat), CN=ArticleExt(id=1242132386700406786, articleId=1242132384125100825, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=维药异常黑胆质成熟剂对异常黑胆质大鼠心肌缺血再灌注损伤的影响, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=为探讨不同剂量异常黑胆质成熟剂对异常黑胆质载体大鼠心肌缺血再灌注损伤的影响,将72 只异常黑胆质模型大鼠和24 只健康雄性SD 大鼠随机分为正常假手术组模型假手术组正常缺血再灌注组模型缺血再灌注组成熟剂干预组(低剂量中剂量及高剂量组)阿托伐他汀干预组8 组各12 只。采用酶联免疫法(ELISA)检测各组大鼠血清心肌酶及肌钙蛋白的水平;苏木精—伊红(HE)染色及高倍电镜方法观察不同组别大鼠心肌组织及超微结构的变化。成熟剂干预组大鼠心肌酶及肌钙蛋白水平明显低于模型缺血再灌注组,其中中剂量组最低;HE 染色心肌组织变化显示,成熟剂干预组大鼠心肌水肿肌纤维增殖较模型组明显;中剂量组大鼠心肌组织损伤最轻。中到高剂量的异常黒胆质成熟剂对缺血再灌注损伤的保护作用可能优于阿托伐他汀,但尚需要进一步的研究来证实。, correspAuthors=null, authorNote=阿布都乃比·麦麦提艾力,主治医师,研究方向为维医异常黑胆质证在心肌缺血再灌注损伤中的作用机制,电子信箱:nebi-boss@hotmail.com, correspAuthorsNote=哈木拉提·吾甫尔(通信作者),教授,研究方向为复杂性疾病维医病症机制,电子信箱:nebi_boss@163.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=3liC8FVtSuD65jH6uI7SYA==, pdfFileSize=2564115, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=1. 新疆医科大学第一附属医院, 乌鲁木齐830054;
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科技导报
| 研究论文 2014, 32(23): 62-66
维药异常黑胆质成熟剂对异常黑胆质大鼠心肌缺血再灌注损伤的影响
全屏
阿布都乃比·麦麦提艾力1 , 木拉提·阿布都热合曼1 , 艾斯卡尔·沙比提1 , 艾力·艾比布拉1 , 哈木拉提·吾甫尔2
作者信息
1. 新疆医科大学第一附属医院, 乌鲁木齐830054;
2. 新疆医科大学维吾尔医学院, 乌鲁木齐830011
通讯作者:
哈木拉提·吾甫尔(通信作者),教授,研究方向为复杂性疾病维医病症机制,电子信箱:nebi_boss@163.com
Effects of Uyghur Medicine Munziq on the Myocardial Ischemiareperfusion Injury of Rats with the Abnormal Savda Syndrome
Affiliations
出版时间: 2014-08-18
doi: 10.3981/j.issn.1000-7857.2014.23.009
文章导航
为探讨不同剂量异常黑胆质成熟剂对异常黑胆质载体大鼠心肌缺血再灌注损伤的影响,将72 只异常黑胆质模型大鼠和24 只健康雄性SD 大鼠随机分为正常假手术组模型假手术组正常缺血再灌注组模型缺血再灌注组成熟剂干预组(低剂量中剂量及高剂量组)阿托伐他汀干预组8 组各12 只。采用酶联免疫法(ELISA)检测各组大鼠血清心肌酶及肌钙蛋白的水平;苏木精—伊红(HE)染色及高倍电镜方法观察不同组别大鼠心肌组织及超微结构的变化。成熟剂干预组大鼠心肌酶及肌钙蛋白水平明显低于模型缺血再灌注组,其中中剂量组最低;HE 染色心肌组织变化显示,成熟剂干预组大鼠心肌水肿肌纤维增殖较模型组明显;中剂量组大鼠心肌组织损伤最轻。中到高剂量的异常黒胆质成熟剂对缺血再灌注损伤的保护作用可能优于阿托伐他汀,但尚需要进一步的研究来证实。
成熟剂
/
异常黑胆质
/
大鼠
/
心肌缺血再灌注损伤
This paper aims to investigate the effects of different doses of abnormal Savda Munziq on myocardial ischemia-reperfusion injury (MI/RI) in rats with the abnormal Savda syndrome. Seventy-two rats with abnormal Savda syndrome and 24 healthy ones were selected and divided into eight groups: ischemia-reperfusion model group, high dose maturation agent group, middle dose group mature agent, small doses of maturation agent group, normal ischemia-reperfusion group, model sham group and atorvastatin intervention group (positive control group). Each group contained 12 rats. The enzyme-linked immunosorbent assay (ELISA) was used to detect the serum myocardial enzyme and troponin levels, and hematoxylin and eosin (HE) staining was used to observe changes of the myocardial tissues in the different groups. The results showed that in the Munziq intervention groups, the serum creatine kinase and troponin levels were significantly lower than those in the model group, and the middle-dose group showed the lowest levels. The HE staining of myocardial tissue showed that the myocardial edema and muscle fiber proliferation levels were significantly higher in the Munziq intervention groups than in the model ischemia-reperfusion injury group, and the middle-dose group showed the least cardiac tissue damage. Moderate to high doses of abnormal Savda Munziq may be more effective on abnormal Savda ischemia-reperfusion injury in rats than atorvastatin, but further studies are still needed to confirm the conclusion.
Munziq
/
abnormal Savda syndrome
/
rats
/
ischemia-reperfusion injury
阿布都乃比·麦麦提艾力, 木拉提·阿布都热合曼, 艾斯卡尔·沙比提, 艾力·艾比布拉, 哈木拉提·吾甫尔.
维药异常黑胆质成熟剂对异常黑胆质大鼠心肌缺血再灌注损伤的影响.
科技导报,
2014
, 32
(23)
: 62
-66
.
DOI: 10.3981/j.issn.1000-7857.2014.23.009
MAIMAITIAILI Abudunaibi, ABUDUREHEMAN Mulati, SHABITI Aisikaer, AIBIBULA Aili, UPUR Halmurat.
Effects of Uyghur Medicine Munziq on the Myocardial Ischemiareperfusion Injury of Rats with the Abnormal Savda Syndrome[J].
Science & Technology Review ,
2014
, 32
(23)
: 62
-66
.
DOI: 10.3981/j.issn.1000-7857.2014.23.009
2014年第32卷第23期
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文章信息
doi: 10.3981/j.issn.1000-7857.2014.23.009
接收时间:2014-04-21
首发时间:2014-08-26
出版时间:2014-08-18
收稿日期:2014-04-21
修回日期:2014-05-26
通讯作者:
哈木拉提·吾甫尔(通信作者),教授,研究方向为复杂性疾病维医病症机制,电子信箱:nebi_boss@163.com
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2014.23.009
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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