Article(id=1242130750238163062, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242130734488556105, articleNumber=null, orderNo=null, doi=10.3981/j.issn.1000-7857.2013.23.011, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1355932800000, receivedDateStr=2012-12-20, revisedDate=1370188800000, revisedDateStr=2013-06-03, acceptedDate=null, acceptedDateStr=null, onlineDate=1376755200000, onlineDateStr=2013-08-18, pubDate=1376755200000, pubDateStr=2013-08-18, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1376755200000, onlineIssueDateStr=2013-08-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774076648527, creator=sys-migrate, updateTime=1774076648527, updator=sys-migrate, issue=Issue{id=1242130734488556105, tenantId=1146029695717560320, journalId=1146031591421210625, year='2013', volume='31', issue='23', pageStart='1', pageEnd='96', issueExtLink='null', onlineDate='null', pubDate='1376755200000', pubDateStr='2013-08-18', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774076644773, creator='sys-migrate', updateTime=1774076644773, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=62, endPage=67, ext={EN=ArticleExt(id=1242130755145503396, articleId=1242130750238163062, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Clinical Epidemiology Investigation of Vitiligo and Correlation Research of Immune Function in View of Syndrome Characteristics of Traditional Uighur Medicine, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=In this paper the epidemiology of vitiligo and immune function in view of syndrome characteristics of traditional Uighur medicine are studied. Epidemiological investigation for syndrome characteristics of the traditional Uygur medicine in vitiligo patients who stayed in the department of Dermatology of the Kashgar Uighur Medical Hospital was introduced, including general information and clinical symptoms. The factors including CD3⁺, CD4⁺, CD8⁺, CD25⁺, IL-2, IL-4, IL-6, IL-8, ICAM-1, IFN-γ, TNF-а, were respectively detected by flow cytometry technique and enzyme-linked immunosorbent assay (ELISA) in whole blood. The results show that the female patients (57.92%) outnumber the male patients (42.08%). The amount of patients aging among 3-15 (36.61%) is more than that of the other aging groups. The proportions of four abnormal Hilit groups are descripted as the following order: Abnormal Balgham group> Abnormal Savda group>Abnormal Sapra group>Abnormal Khan group. In comparison with the normal group (P<0.05), the plasma level of vitiligo patients on CD8⁺, IL-2, IL-6, IL-8, IFN-γ, TNF-а, ICAM-1 increased and the level on CD3⁺, CD25⁺, IL-4 decreased in abnormal and normal balhgam syndrome. There were not obviously differences among level of CD3⁺CD25⁺IL-4, IL-6, IL-8, in abnormal and normal Balgham syndrome(P<0.05). It is concluded that the abnormal Balgham is the main syndrome in the traditional Uighur medicine. The level of CD3⁺, CD25⁺, IL-4, IL-6, IL-8 are closely related with Uighur Medicine Abnormal Balgham, especially the change of some immunity parameter may be indicated to the abnormal Abnormal Balgham of vitiligo., authors=AMAT Nurmuhammat¹, EKIM Mahsum¹, EIZIZ Ranagul¹, SIDIK Axirjan², TRIM Halidam², TOHTI Patigul², OBUL Buhliqam², TURDI Nabijan², UPUR Halmurat¹, authorsList=AMAT Nurmuhammat;EKIM Mahsum;EIZIZ Ranagul;SIDIK Axirjan;TRIM Halidam;TOHTI Patigul;OBUL Buhliqam;TURDI Nabijan;UPUR Halmurat, authorCompany=1. Inistitute of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi 830011, China;2. Kashgar Uighur Medicine Hospital, Kashgar 844000, Xinjiang Uygur Autonomous Region, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=Xv1xl1tGEFUtoqScgEvHPw==, pdfFileSize=1163957, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242130754063368329, articleId=1242130750238163062, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=白癜风患者维医证候学特征及其临床流行病学调查与免疫功能变化的相关性, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=通过观察新疆白癜风患者的维医证候特征及其临床流行病学特征,探讨白癜风患者各体液证型与免疫功能变化的关系。采用流式细胞技术、酶联免疫吸附试验(ELISA法)检测全血中CD3⁺、CD4⁺、CD8⁺、CD25⁺、白介素-2(IL-2)、白介素-4(IL-4)、白介素-6(IL-6)、白介素-8(IL-8)、细胞间附分子(ICAM-1)、γ干扰素(IFN-γ)、肿瘤坏死因子(TNF-а)、粒细胞-巨噬细胞集落刺激因子(GM-CSF)和干细胞因子(SCF)等指标,并进行分析。结果显示,183例白癜风患者中女性106例(57.92%),男性77例(42.08%),3~15岁之间的患者比例较高(36.61%),白癜风患者在不同异常体液中的构成比不同,黏液质型白癜风组107例(占58.47%)和非黏液质型白癜风组76例(占41.53%),其构成比大小顺序为:异常黏液质型白癜风>异常黑胆质型白癜风>异常胆液质型白癜风>异常血液质型白癜风。与正常对照组相比,CD8⁺、IL-2、IL-6、IL-8、IFN-γ、TNF-а、ICAM-1在异常黏液质型白癜风组和非异常黏液质型白癜风组均升高(P<0.05);CD3⁺、CD25⁺、IL-4在异常黏液质型白癜风组和非异常黏液质型白癜风组均降低 (P<0.05)。与非异常黏液质型白癜风组相比,CD8⁺、IL-6、IL-8在异常黏液质型白癜风患者升高明显(P<0.05);CD3⁺、CD25⁺、IL-4在异常黏液质型白癜风患者降低明显(P<0.05),CD4⁺、CD4⁺/D8⁺,在各组间比较无差异(P>0.05)。由此推断,异常黏液质型白癜风是白癜风维医主要证型,且白癜风患者存在自身免疫调节的异常,异常黏液质型白癜风患者的免疫功能紊乱程度较非异常黏液质型白癜风患者更为明显。, authors=努尔买买提·艾买提¹, 麦合苏木·艾克木¹, 热娜古丽·艾则孜¹, 阿西尔江·斯迪克², 哈力旦木·铁力木², 帕提古丽·托乎提², 布合力其木·巴克², 乃比江·吐尔地², 哈木拉提·吾甫尔¹, authorsList=努尔买买提·艾买提;麦合苏木·艾克木;热娜古丽·艾则孜;阿西尔江·斯迪克;哈力旦木·铁力木;帕提古丽·托乎提;布合力其木·巴克;乃比江·吐尔地;哈木拉提·吾甫尔, authorCompany=1. 新疆医科大学维吾尔医学院, 乌鲁木齐 830011;2. 喀什地区维吾尔医医院, 新疆喀什 844000, correspAuthors=null, authorNote=null, correspAuthorsNote=哈木拉提·吾甫尔,教授,研究方向为新疆重大疾病及其中西维医干预,电子信箱:halmurat@263.net, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=iekwSgJAxwuyCMzraMd4dQ==, pdfFileSize=1163957, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1242130752402423931, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=CN, orderNo=1, keyword=白癜风), Keyword(id=1242130753677492349, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=CN, orderNo=1, keyword=维医证候), Keyword(id=1242130753761378432, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=CN, orderNo=1, keyword=特征), Keyword(id=1242130753853653123, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=CN, orderNo=1, keyword=临床流行病学), Keyword(id=1242130753937539206, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=CN, orderNo=1, keyword=免疫功能变化), Keyword(id=1242130754658964127, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=EN, orderNo=1, keyword=vitiligo), Keyword(id=1242130754742850208, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=EN, orderNo=1, keyword=syndrome characteristic), Keyword(id=1242130754826736289, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=EN, orderNo=1, keyword=traditional Uygur medicine), Keyword(id=1242130754914816674, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=EN, orderNo=1, keyword=clinical epidemiology), Keyword(id=1242130755007091363, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242130750238163062, language=EN, orderNo=1, keyword=immunity parameter)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1125356956822126595, delFlag=0, nameCn=科技导报, nameEn=Science & Technology Review, nameHistory1=null, nameHistory2=null, issn=1000-7857, eissn=, cn=11-1421/N, coden=null, periodic=3, language=CN, oaType=0, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=wfghvu3bhh/dKxuZ+ucVHA==, journalPrice=null, startedYear=null, abbrevIsoEn=Sci Technol Rev, journalRemark=null, publicationField=null, createdTime=null, updatedTime=1774230116083, createdBy=null, updatedBy=13041195026, firstLetterCn=S, firstLetterEn=S, subjectCode=Natural Sciences, subjectName=自然科学, subjectCodeEn=Natural Sciences, subjectNameEn=null, picCn=wfghvu3bhh/dKxuZ+ucVHA==, picEn=yjSfclmpNm7ihn9NbTZ69g==, jcr=null, cjcr=null, exts=[JournalExt(id=1242774439910290156, language=CN, name=科技导报, nameHistory1=null, nameHistory2=null, managedBy=中国科学技术协会, sponsoredBy=中国科学技术协会, publishedBy=科技导报社, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/CN/home, createdTime=1774230116107, updatedTime=1774230116107, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/CN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.cast.org.cn/webm, submissionEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionReviewUrl=https://kjdbauthor.cast.org.cn/webm, submissionCeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionAeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, option={"copyright":""}), JournalExt(id=1242774439960621805, language=EN, name=Science & Technology Review, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/EN/home, createdTime=1774230116119, updatedTime=1774230116119, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/EN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionReviewUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionCeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionAeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, option={"copyright":""})], databaseList=null, tenantJournalId=1146031591421210625, websiteList=[Website(id=1146104741081231361, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/CN, language=CN, createTime=1751182263881, createBy=18614031015, updateTime=1751778001962, updateBy=18614031015, name=科技导报, tplId=1146099689490845704, title=科技导报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1148021146403992296, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=articleTextType, value=kx, createTime=1751639170504, updateTime=1751639170504, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146378826469, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=banner, value=null, createTime=1751639170498, updateTime=1751639170498, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146366243556, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1751639170495, updateTime=1751639170495, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146395603687, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic, createTime=1751639170502, updateTime=1751639170502, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146387215078, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1751639170500, updateTime=1751639170500, creator=18614031015, updator=18614031015)]), Website(id=1146105254833139715, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/EN, language=EN, createTime=1751182386363, createBy=18614031015, updateTime=1753500121937, updateBy=18614031015, name=科技导报, tplId=1146101810881728533, title=Science & Technology Review, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1155838567709528217, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=articleTextType, value=kx, createTime=1753502988984, updateTime=1753502988984, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567692750998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=banner, value=null, createTime=1753502988980, updateTime=1753502988980, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567688556693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1753502988979, updateTime=1753502988979, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567705333912, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic, createTime=1753502988983, updateTime=1753502988983, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567701139607, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1753502988982, updateTime=1753502988982, creator=18614031015, updator=18614031015)])], journalTitle=科技导报, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Science & Technology Review, journalPhotoCn=wfghvu3bhh/dKxuZ+ucVHA==, journalPhotoEn=yjSfclmpNm7ihn9NbTZ69g==, journalFirstLetter=S, journalRecommend=null, journalNew=null, journalCollection=1, jcrJf=null, cjcrJf=0.91, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=null, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2013.23.011, detailUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/10.3981/j.issn.1000-7857.2013.23.011, pdfUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/PDF/10.3981/j.issn.1000-7857.2013.23.011, pdfUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/PDF/10.3981/j.issn.1000-7857.2013.23.011, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1376755200000, fullTextJson=null, articleText=null, reference=null)