Article(id=1309634779117609594, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, articleNumber=null, orderNo=null, doi=10.12048/j.issn.1674-229X.2026.01.011, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1742400000000, receivedDateStr=2025-03-20, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1790170863179, onlineDateStr=2026-09-23, pubDate=1769270400000, pubDateStr=2026-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1790170863179, onlineIssueDateStr=2026-09-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1790170863179, creator=13701087609, updateTime=1790170863179, updator=13701087609, issue=Issue{id=1309634747681304819, tenantId=1146029695717560320, journalId=1227999776411738115, year='2026', volume='36', issue='1', pageStart='1', pageEnd='80', issueExtLink='null', onlineDate='null', pubDate='1769270400000', pubDateStr='2026-01-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1790170855683, creator='13701087609', updateTime=1790219109143, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1309837137445482891, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1309837137445482892, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=59, endPage=66, ext={EN=ArticleExt(id=1309634779281187453, articleId=1309634779117609594, tenantId=1146029695717560320, journalId=1227999776411738115, language=EN, title=Pharmacological Properties of 18β-Glycyrrhetinic Acid and Its Research Progress in Skin Diseases, columnId=null, journalTitle=Pharmacy Today, columnName=null, runingTitle=null, highlight=null, articleAbstract=
18β-Glycyrrhetinic Acid, a naturally occurring active compound extracted from licorice, has recently garnered significant attention in the field of dermatological research. The pathophysiology of skin diseases is often highly complex, involving pathological processes such as inflammatory responses, oxidative stress, and cellular damage, which can severely impact patients' quality of life. Despite the availability of various treatment options, some medications are hampered by significant side effects or insufficient efficacy, highlighting the need for the development of safe and effective natural natural drugs. 18β-Glycyrrhetinic Acid stands out due to its remarkable pharmacological properties, including anti-inflammatory, antioxidant, wound-healing, and antitumor effects. Its ability to alleviate or improve symptoms of skin diseases through multiple mechanisms has led to widespread recognition of its biological activity and therapeutic potential. This review aims to summarize the research advancements on 18β-Glycyrrhetinic Acid in skin diseases, analyze its mechanisms of action, and discuss its clinical clinical prospects, thereby providing a scientific basis for future investigations and applications.
, authors=Ying XIE
1, Hankun CHEN
2, Ying LIN
3, Wei ZHU
1, *, authorsList=Ying XIE, Hankun CHEN, Ying LIN, Wei ZHU, authorCompany=null, correspAuthors=Wei ZHU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1309634779562205822, articleId=1309634779117609594, tenantId=1146029695717560320, journalId=1227999776411738115, language=CN, title=18β-甘草次酸的药理特性及在皮肤疾病中的研究进展, columnId=1228268593092162252, journalTitle=今日药学, columnName=药学进展, runingTitle=null, highlight=null, articleAbstract=
18β-甘草次酸(18β-Glycyrrhetinic Acid)是一种从甘草中提取的天然活性化合物,近期在皮肤相关疾病研究中备受关注。皮肤疾病的发病机制复杂,常伴随炎症反应、氧化应激及细胞损伤等病理过程,严重影响患者生活质量。尽管现有治疗手段丰富,但部分药物因副作用大或疗效有限而无法满足临床需求,开发安全高效的天然药物已成为研究热点。18β-甘草次酸具有显著的抗炎、抗氧化、促进伤口愈合和抗肿瘤等药理作用,能够通过多种机制改善皮肤疾病的症状,其生物活性及治疗潜力得到广泛认可。本文旨在综述18β-甘草次酸在皮肤疾病中的研究进展,分析其作用机制和临床应用前景,为未来的研究和应用提供科学依据。
, authors=谢英
1, 陈汉坤
2, 林颖
3, 朱伟
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