Article(id=1309634637060727004, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634614356968036, articleNumber=null, orderNo=null, doi=10.12048/j.issn.1674-229X.2026.03.010, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1745424000000, receivedDateStr=2025-04-24, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1790170829309, onlineDateStr=2026-09-23, pubDate=1774368000000, pubDateStr=2026-03-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1790170829309, onlineIssueDateStr=2026-09-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1790170829309, creator=13701087609, updateTime=1790170829309, updator=13701087609, issue=Issue{id=1309634614356968036, tenantId=1146029695717560320, journalId=1227999776411738115, year='2026', volume='36', issue='3', pageStart='161', pageEnd='240', issueExtLink='null', onlineDate='null', pubDate='1774368000000', pubDateStr='2026-03-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1790170823897, creator='13701087609', updateTime=1790219059643, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1309836929789682362, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634614356968036, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1309836929789682363, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634614356968036, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=219, endPage=223, ext={EN=ArticleExt(id=1309634637203333341, articleId=1309634637060727004, tenantId=1146029695717560320, journalId=1227999776411738115, language=EN, title=Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital, columnId=null, journalTitle=Pharmacy Today, columnName=null, runingTitle=null, highlight=null, articleAbstract=
OBJECTIVE

To investigate the off-label use of pregabalin in the outpatient department of a hospital, analyze the types, reasons, and potential risks of such usage, and provide reference for improving the safety and rationality of its use.

METHODS

A total of 2 183 outpatient prescriptions containing pregabalin issued between May 2023 and April 2024 were selected.Patient basic information, demographics, clinical diagnoses, and concomitant medications were recorded.

RESULTS

Among the 2 183 prescriptions, 421 (19.29%) involved off-label use.The primary categories included off-label indications (94.06%), off-label patient populations (1.66%), and concomitant medications (4.28%). Additionally, 281 prescriptions (12.87%) were deemed irrational, mainly due to inappropriate indications (26 cases) and altered dosing frequency (255 cases).

CONCLUSION

Off-label use of pregabalin is prevalent in the dermatology outpatient department of the hospital. However, significant irrational prescribing practices exist.The hospital should refine and enforce relevant systems, enhance physician training and patient education, and conduct in‐depth specialized prescription reviews and risk assessments to ensure medication safety and rational use.

, authors=Changzhen LI1, Zhiyuan FU1, Xiaobing WANG2, *, authorsList=Changzhen LI, Zhiyuan FU, Xiaobing WANG, authorCompany=null, correspAuthors=Xiaobing WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1309634637668901086, articleId=1309634637060727004, tenantId=1146029695717560320, journalId=1227999776411738115, language=CN, title=皮肤病专科医院门诊普瑞巴林超说明书用药情况分析, columnId=1228268590097433397, journalTitle=今日药学, columnName=超说明书用药专栏, runingTitle=null, highlight=null, articleAbstract=
目的

了解某院门诊普瑞巴林超说明书用药的情况,探讨其超说明书用药的类型、原因及潜在风险,为提升该院该药使用的安全性与合理性提供参考依据。

方法

抽取该院2023年5月~2024年4月门诊开具含普瑞巴林的处方2183张,收集患者的基本信息、临床诊断及联合用药情况。

结果

2183张处方中,普瑞巴林超说明书用药处方有421张,超说明书用药率为19.29%。其主要集中在超适应证(94.06%)、超适用人群(1.66%)及联合用药(4.28%)。不合理用药处方281张,占比12.87%,主要为适应证不适宜(26张)和改变用药频次(255张)。

结论

普瑞巴林在皮肤科门诊的超说明书用药现象较为普遍。但存在较多不合理用药行为,医院应完善和落实相关制度,加强医生培训和患者宣教,深入开展专项点评和风险评估,以保障患者用药安全与合理。

, authors=李嫦珍1, 付志媛1, 王小兵2, *, authorsList=李嫦珍, 付志媛, 王小兵, authorCompany=null, correspAuthors=王小兵, authorNote=

李嫦珍,主管药师,研究方向:临床药学

, correspAuthorsNote=

*

王小兵,主任医师,研究方向:皮肤性病学,E-mail:
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李嫦珍,主管药师,研究方向:临床药学

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皮肤病专科医院门诊普瑞巴林超说明书用药情况分析
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李嫦珍 1 , 付志媛 1 , 王小兵 2, *
今日药学 | 超说明书用药专栏 2026,36(3): 219-223
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今日药学 |超说明书用药专栏 2026 , 36 (3) : 219 -223
皮肤病专科医院门诊普瑞巴林超说明书用药情况分析
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李嫦珍1, 付志媛1, 王小兵2, *
作者信息
  • 1.江西省皮肤病专科医院,江西 南昌 330001
  • 2.江西省皮肤病临床医学研究中心,江西 南昌 330001
通讯作者:

*

王小兵,主任医师,研究方向:皮肤性病学,E-mail:
作者简介:

李嫦珍,主管药师,研究方向:临床药学

Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital
Changzhen LI1, Zhiyuan FU1, Xiaobing WANG2, *
Affiliations
  • 1.Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi 330001, China
  • 2.Jiangxi Provincial Clinical Research Center For Skin Diseases, Nanchang, Jiangxi 330001, China
出版时间: 2026-03-25 doi: 10.12048/j.issn.1674-229X.2026.03.010
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目的

了解某院门诊普瑞巴林超说明书用药的情况,探讨其超说明书用药的类型、原因及潜在风险,为提升该院该药使用的安全性与合理性提供参考依据。

方法

抽取该院2023年5月~2024年4月门诊开具含普瑞巴林的处方2183张,收集患者的基本信息、临床诊断及联合用药情况。

结果

2183张处方中,普瑞巴林超说明书用药处方有421张,超说明书用药率为19.29%。其主要集中在超适应证(94.06%)、超适用人群(1.66%)及联合用药(4.28%)。不合理用药处方281张,占比12.87%,主要为适应证不适宜(26张)和改变用药频次(255张)。

结论

普瑞巴林在皮肤科门诊的超说明书用药现象较为普遍。但存在较多不合理用药行为,医院应完善和落实相关制度,加强医生培训和患者宣教,深入开展专项点评和风险评估,以保障患者用药安全与合理。

普瑞巴林  /  超说明书用药  /  瘙痒  /  合理用药
OBJECTIVE

To investigate the off-label use of pregabalin in the outpatient department of a hospital, analyze the types, reasons, and potential risks of such usage, and provide reference for improving the safety and rationality of its use.

METHODS

A total of 2 183 outpatient prescriptions containing pregabalin issued between May 2023 and April 2024 were selected.Patient basic information, demographics, clinical diagnoses, and concomitant medications were recorded.

RESULTS

Among the 2 183 prescriptions, 421 (19.29%) involved off-label use.The primary categories included off-label indications (94.06%), off-label patient populations (1.66%), and concomitant medications (4.28%). Additionally, 281 prescriptions (12.87%) were deemed irrational, mainly due to inappropriate indications (26 cases) and altered dosing frequency (255 cases).

CONCLUSION

Off-label use of pregabalin is prevalent in the dermatology outpatient department of the hospital. However, significant irrational prescribing practices exist.The hospital should refine and enforce relevant systems, enhance physician training and patient education, and conduct in‐depth specialized prescription reviews and risk assessments to ensure medication safety and rational use.

pregabalin  /  off-label drug use  /  itch  /  rational use of medicines
李嫦珍, 付志媛, 王小兵. 皮肤病专科医院门诊普瑞巴林超说明书用药情况分析. 今日药学, 2026 , 36 (3) : 219 -223 . DOI: 10.12048/j.issn.1674-229X.2026.03.010
Changzhen LI, Zhiyuan FU, Xiaobing WANG. Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital[J]. Pharmacy Today, 2026 , 36 (3) : 219 -223 . DOI: 10.12048/j.issn.1674-229X.2026.03.010
  • 江西省卫生健康委科技计划项目(202410551)
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doi: 10.12048/j.issn.1674-229X.2026.03.010
  • 接收时间:2025-04-24
  • 首发时间:2026-09-23
  • 出版时间:2026-03-25
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  • 收稿日期:2025-04-24
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江西省卫生健康委科技计划项目(202410551)
作者信息
    1.江西省皮肤病专科医院,江西 南昌 330001
    2.江西省皮肤病临床医学研究中心,江西 南昌 330001

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王小兵,主任医师,研究方向:皮肤性病学,E-mail:
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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