Article(id=1309634294151217340, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634291257143967, articleNumber=null, orderNo=null, doi=10.12048/j.issn.1674-229X.2026.06.006, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1760112000000, receivedDateStr=2025-10-11, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1790170747554, onlineDateStr=2026-09-23, pubDate=1782316800000, pubDateStr=2026-06-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1790170747554, onlineIssueDateStr=2026-09-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1790170747554, creator=13701087609, updateTime=1790170747554, updator=13701087609, issue=Issue{id=1309634291257143967, tenantId=1146029695717560320, journalId=1227999776411738115, year='2026', volume='36', issue='6', pageStart='401', pageEnd='480', issueExtLink='null', onlineDate='null', pubDate='1782316800000', pubDateStr='2026-06-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1790170746864, creator='13701087609', updateTime=1790218948815, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1309836464964337802, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634291257143967, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1309836464964337803, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634291257143967, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=434, endPage=441, ext={EN=ArticleExt(id=1309634294461595837, articleId=1309634294151217340, tenantId=1146029695717560320, journalId=1227999776411738115, language=EN, title=The Knowledge Graph Analysis of the Research Progress on the Chinese Herb Morinda officinalis How. Using CiteSpace, columnId=null, journalTitle=Pharmacy Today, columnName=null, runingTitle=null, highlight=null, articleAbstract=
OBJECTIVE

To explore the global research progress and future trends of Morinda officinalis How. (Bajitian) from 2000 to 2024.

METHODS

Using CiteSpace software combined with bibliometric methods, relevant Chinese and English literature on Bajitian were collected from the China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, VIP Biomedical Database, and Web of Science. Duplicate literatures were eliminated with NoteExpress software, and visual analysis and knowledge graph construction were performed on the publication countries, publication volumes, authors, institutions, keywords, etc., using CiteSpace software.

RESULTS

A total of 2 712 Chinese articles and 374 English articles were included. From 2000 to 2024, the publication volume of research related to Bajitian had steadily increased, and both domestic and international research entered a rapid development stage in 2009. China was the leading country in Bajitian research, and the core domestic research institution was Guangzhou University of Chinese Medicine. Research on Bajitian covered various aspects such as content determination, pharmacological effects, mechanisms of action, and processing methods. Internationally, the focus had been primarily on the pharmacological effects and active ingredients of Bajitian extracts.

CONCLUSION

Research on Bajitian had entered a diversified development stage, covering multiple aspects including medication rules, chemical constituents, content determination, fingerprint spectrum, famous TCM physician experience, and clinical application. After 2020, studies using data mining, network pharmacology, and other technologies for molecular docking and mechanisms of action have become a research hotspot, mainly focusing on anti-inflammation, anti-depression, anti-osteoporosis, anti-oxidation, and the treatment of ovarian and testicular dysfunction.

, authors=Hancheng LI1a, Xiaoying LI1a, Chaohua LUO2, Yuting HUANG1a, Wenhua LIU1b, Rimeng CHEN3, Deyun MA1a, Zhixian MO2, *, authorsList=Hancheng LI, Xiaoying LI, Chaohua LUO, Yuting HUANG, Wenhua LIU, Rimeng CHEN, Deyun MA, Zhixian MO, authorCompany=null, correspAuthors=Zhixian MO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1309634295271096510, articleId=1309634294151217340, tenantId=1146029695717560320, journalId=1227999776411738115, language=CN, title=中药巴戟天研究进展的CiteSpace知识图谱分析, columnId=1228268589086606089, journalTitle=今日药学, columnName=论著, runingTitle=null, highlight=null, articleAbstract=
目的

探讨2000~2024年间全球视域下的巴戟天Morinda officinalis How.的科研进展以及未来趋势。

方法

通过CiteSpace软件与文献计量学法相结合,分别从中国学术期刊全文数据库(CNKI)、万方数据知识服务平台、维普生物医学数据库和Web of Science数据库中,收集巴戟天相关的中英文文献。利用NoteExpress软件去重,再采用CiteSpace等软件分别对中英文文献的发文国家、发文量、作者、发文机构、关键词等进行可视化分析和知识图谱的构建。

结果

纳入中文文献2 712篇,英文文献374篇。在2000~2024年间,与巴戟天相关研究的发文量在持续增长,国内国际都在2009年进入快速发展阶段。中国是研究巴戟天的主要国家,国内的主要核心研究机构是广州中医药大学,对巴戟天的研究涉及到了多方面。例如含量测定、药理作用、作用机制、炮制等方面。国际上对巴戟天的研究主要聚焦于巴戟天提取物的药理作用和活性成分。

结论

巴戟天的研究已进入多元化的发展阶段,覆盖了用药规律、化学成分、含量测定、指纹图谱、中药、名医经验以及临床应用等多方面。2020年后利用数据挖掘、网络药理学等科技手段进行分子对接、作用机制的研究,研究热点一直聚焦于抗炎、抗抑郁、骨质疏松、抗氧化、治疗卵巢以及睾丸功能障碍等。

, authors=李汉成1a, 李晓莹1a, 罗超华2, 黄玉婷1a, 刘文华1b, 陈日檬3, 马德运1a, 莫志贤2, *, authorsList=李汉成, 李晓莹, 罗超华, 黄玉婷, 刘文华, 陈日檬, 马德运, 莫志贤, authorCompany=null, correspAuthors=莫志贤, authorNote=

李汉成,博士,副教授,硕士生导师,研究方向:中药药理学

, correspAuthorsNote=

*

莫志贤,教授,博士生导师,研究方向:中药药理学,E-mail:
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李汉成,博士,副教授,硕士生导师,研究方向:中药药理学

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中药巴戟天研究进展的CiteSpace知识图谱分析
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李汉成 1a , 李晓莹 1a , 罗超华 2 , 黄玉婷 1a , 刘文华 1b , 陈日檬 3 , 马德运 1a , 莫志贤 2, *
今日药学 | 论著 2026,36(6): 434-441
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今日药学 |论著 2026 , 36 (6) : 434 -441
中药巴戟天研究进展的CiteSpace知识图谱分析
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李汉成1a, 李晓莹1a, 罗超华2, 黄玉婷1a, 刘文华1b, 陈日檬3, 马德运1a, 莫志贤2, *
作者信息
  • 1a.肇庆学院,食品与制药工程学院,广东 肇庆 526061
  • 1b.肇庆学院,南药研究开发重点实验室,广东 肇庆 526061
  • 2.南方医科大学中医药学院,广东 广州 510515
  • 3.湛江市食品药品检验所,广东 湛江 524008
通讯作者:

*

莫志贤,教授,博士生导师,研究方向:中药药理学,E-mail:
作者简介:

李汉成,博士,副教授,硕士生导师,研究方向:中药药理学

The Knowledge Graph Analysis of the Research Progress on the Chinese Herb Morinda officinalis How. Using CiteSpace
Hancheng LI1a, Xiaoying LI1a, Chaohua LUO2, Yuting HUANG1a, Wenhua LIU1b, Rimeng CHEN3, Deyun MA1a, Zhixian MO2, *
Affiliations
  • 1a.School of Food and Pharmaceutical Engineering, Zhaoqing University, Zhaoqing, Guangdong 526061, China
  • 1b.Key Laboratory for Research and Utilization of Southern Medicine, Zhaoqing University, Zhaoqing, Guangdong 526061, China
  • 2.School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China
  • 3.Zhanjiang Institute for Food and Drug Control, Zhanjiang, Guangdong 524008, China
出版时间: 2026-06-25 doi: 10.12048/j.issn.1674-229X.2026.06.006
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目的

探讨2000~2024年间全球视域下的巴戟天Morinda officinalis How.的科研进展以及未来趋势。

方法

通过CiteSpace软件与文献计量学法相结合,分别从中国学术期刊全文数据库(CNKI)、万方数据知识服务平台、维普生物医学数据库和Web of Science数据库中,收集巴戟天相关的中英文文献。利用NoteExpress软件去重,再采用CiteSpace等软件分别对中英文文献的发文国家、发文量、作者、发文机构、关键词等进行可视化分析和知识图谱的构建。

结果

纳入中文文献2 712篇,英文文献374篇。在2000~2024年间,与巴戟天相关研究的发文量在持续增长,国内国际都在2009年进入快速发展阶段。中国是研究巴戟天的主要国家,国内的主要核心研究机构是广州中医药大学,对巴戟天的研究涉及到了多方面。例如含量测定、药理作用、作用机制、炮制等方面。国际上对巴戟天的研究主要聚焦于巴戟天提取物的药理作用和活性成分。

结论

巴戟天的研究已进入多元化的发展阶段,覆盖了用药规律、化学成分、含量测定、指纹图谱、中药、名医经验以及临床应用等多方面。2020年后利用数据挖掘、网络药理学等科技手段进行分子对接、作用机制的研究,研究热点一直聚焦于抗炎、抗抑郁、骨质疏松、抗氧化、治疗卵巢以及睾丸功能障碍等。

巴戟天  /  知识图谱  /  可视化分析  /  研究进展  /  CiteSpace
OBJECTIVE

To explore the global research progress and future trends of Morinda officinalis How. (Bajitian) from 2000 to 2024.

METHODS

Using CiteSpace software combined with bibliometric methods, relevant Chinese and English literature on Bajitian were collected from the China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, VIP Biomedical Database, and Web of Science. Duplicate literatures were eliminated with NoteExpress software, and visual analysis and knowledge graph construction were performed on the publication countries, publication volumes, authors, institutions, keywords, etc., using CiteSpace software.

RESULTS

A total of 2 712 Chinese articles and 374 English articles were included. From 2000 to 2024, the publication volume of research related to Bajitian had steadily increased, and both domestic and international research entered a rapid development stage in 2009. China was the leading country in Bajitian research, and the core domestic research institution was Guangzhou University of Chinese Medicine. Research on Bajitian covered various aspects such as content determination, pharmacological effects, mechanisms of action, and processing methods. Internationally, the focus had been primarily on the pharmacological effects and active ingredients of Bajitian extracts.

CONCLUSION

Research on Bajitian had entered a diversified development stage, covering multiple aspects including medication rules, chemical constituents, content determination, fingerprint spectrum, famous TCM physician experience, and clinical application. After 2020, studies using data mining, network pharmacology, and other technologies for molecular docking and mechanisms of action have become a research hotspot, mainly focusing on anti-inflammation, anti-depression, anti-osteoporosis, anti-oxidation, and the treatment of ovarian and testicular dysfunction.

Morinda officinalis How.  /  knowledge graph  /  visualization analysis  /  research progress  /  CiteSpace
李汉成, 李晓莹, 罗超华, 黄玉婷, 刘文华, 陈日檬, 马德运, 莫志贤. 中药巴戟天研究进展的CiteSpace知识图谱分析. 今日药学, 2026 , 36 (6) : 434 -441 . DOI: 10.12048/j.issn.1674-229X.2026.06.006
Hancheng LI, Xiaoying LI, Chaohua LUO, Yuting HUANG, Wenhua LIU, Rimeng CHEN, Deyun MA, Zhixian MO. The Knowledge Graph Analysis of the Research Progress on the Chinese Herb Morinda officinalis How. Using CiteSpace[J]. Pharmacy Today, 2026 , 36 (6) : 434 -441 . DOI: 10.12048/j.issn.1674-229X.2026.06.006
  • 国家自然科学基金资助项目(81873030)
  • 广东省科技厅项目(KTP20200176)
  • 中国中医药信息学会科研项目(CIA-2025-(KCFH)-001)
  • 肇庆市科技创新指导类项目(肇科〔2025〕25号-No.169)
  • 肇庆学院省级大学生创新创业训练计划项目(S202510580068)
  • 广东省本科高校教学质量与教学改革工程建设项目(52)
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doi: 10.12048/j.issn.1674-229X.2026.06.006
  • 接收时间:2025-10-11
  • 首发时间:2026-09-23
  • 出版时间:2026-06-25
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出版历史
  • 收稿日期:2025-10-11
基金
国家自然科学基金资助项目(81873030)
广东省科技厅项目(KTP20200176)
中国中医药信息学会科研项目(CIA-2025-(KCFH)-001)
肇庆市科技创新指导类项目(肇科〔2025〕25号-No.169)
肇庆学院省级大学生创新创业训练计划项目(S202510580068)
广东省本科高校教学质量与教学改革工程建设项目(52)
作者信息
    1a.肇庆学院,食品与制药工程学院,广东 肇庆 526061
    1b.肇庆学院,南药研究开发重点实验室,广东 肇庆 526061
    2.南方医科大学中医药学院,广东 广州 510515
    3.湛江市食品药品检验所,广东 湛江 524008

通讯作者:

*

莫志贤,教授,博士生导师,研究方向:中药药理学,E-mail:
参考文献
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2种不同金属材料的力学参数
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Family
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Number of
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属
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Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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