今日药学

基于文献计量学对时间药理学的研究现状及热点分析

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张迪梦 ¹ , 吴春兴 ²

今日药学 | 论著 2026,36(7): 512-522

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今日药学 |论著 2026 , 36 (7) : 512 -522

基于文献计量学对时间药理学的研究现状及热点分析

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张迪梦¹, 吴春兴²

作者信息

^1.开封市中医院药学部，河南　开封　475000

^2.滨州市中心医院药剂科，山东　滨州　251700

作者简介:

张迪梦，药师，研究方向：医院药学，E-mail：1448083438@qq.com

The Analysis of Current Status and Hotspots of Chronopharmacology Research Based on Bibliometrics

Dimeng ZHANG¹, Chunxin WU²

Affiliations

^1.Department of Pharmacy, Kaifeng Traditional Chinese Medicine Hospital, Kaifeng, Henan 47500, China

^2.Department of Pharmacy, Binzhou Central Hospital, Binzhou, Shandong 251700, China

出版时间: 2026-07-25 doi: 10.12048/j.issn.1674-229X.2026.07.005

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摘要

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目的

在文献计量学的视角下探讨总结时间药理学的研究成果、热点趋势，以期为本领域的未来研究提供相应借鉴。

方法

以Web of Science为数据来源，并借助多种文献计量学软件进行刊文趋势、作者机构合作、国家/地区合作、文献高被引分析、关键词分析等，以明确本领域的研究现状及热点。

结果

共纳入1 762篇文献，目前本领域研究正受到学者的广泛关注。共有589位学者以及419家机构参与了时间药理学研究，同时本领域研究已具备国际化合作的特点。基于时间药理学的疾病治疗及效果一直是该领域的研究重点，聚类分析获得10个结果；当前研究热点主要集中在疾病治疗的微观层面。

结论

时间药理学研究具有一定的学术价值及临床意义，学者关注度不断增加，相关研究热点持续涌现。未来应在加强学者交流合作的基础上，进一步把握研究热点注重疾病细化研究。

关键词

时间药理学 / 时间药动学 / 时间药效学 / 时间治疗学 / 文献计量学

Abstract

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OBJECTIVE

To systematically explore and summarize the research status and hot trends of chronopharmacology from the perspective of bibliometrics，so as to provide meaningful references for the future research in this field.

METHODS

In this study，relevant articles were collected from Web of Science，and various bibliometric tools were used to conduct corresponding analyses，including publication trends，author and institution collaborations，national (or regional) collaborations，highly cited articles，and keywords which could clarify the research status and hotspots in this field.

RESULTS

A total of 1 762 articles were included，and the research in this field was currently receiving widespread attention from scholars. A total of 589 scholars and 419 institutions worldwide participated in chronopharmacology research，and the research of chronopharmacology had the characteristics of international cooperation. The treatment and efficacy of diseases based on chronopharmacology had always been the research priority in this field，and 10 clusters were obtained through keyword cluster analysis. Meanwhile，the current research hotspots mainly focused on the micro level of disease treatment.

CONCLUSION

The study of chronopharmacology has certain academic value and clinical significance，with increasing attention from scholars and the emergence of related research hotspots. In the future，research should further grasp the research hotspots and focus on refined research on diseases on the basis of strengthening academic exchanges and cooperation.

Key words

chronopharmacology / chronopharmacokinetics / chronopharmacodynamics / chronotherapy / bibliometrics

引用本文

张迪梦, 吴春兴. 基于文献计量学对时间药理学的研究现状及热点分析. 今日药学, 2026 , 36 (7) : 512 -522 . DOI: 10.12048/j.issn.1674-229X.2026.07.005

Dimeng ZHANG, Chunxin WU. The Analysis of Current Status and Hotspots of Chronopharmacology Research Based on Bibliometrics[J]. Pharmacy Today, 2026 , 36 (7) : 512 -522 . DOI: 10.12048/j.issn.1674-229X.2026.07.005

参考文献

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2026年第36卷第7期

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doi: 10.12048/j.issn.1674-229X.2026.07.005

接收时间：2025-10-17
首发时间：2026-10-27
出版时间：2026-07-25

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收稿日期：2025-10-17

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^1.开封市中医院药学部，河南　开封　475000

^2.滨州市中心医院药剂科，山东　滨州　251700

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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