Article(id=1309634547323593198, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634546845442540, articleNumber=null, orderNo=null, doi=10.12048/j.issn.1674-229X.2026.05.002, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1755446400000, receivedDateStr=2025-08-18, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1790170807914, onlineDateStr=2026-09-23, pubDate=1779638400000, pubDateStr=2026-05-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1790170807914, onlineIssueDateStr=2026-09-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1790170807914, creator=13701087609, updateTime=1790170807914, updator=13701087609, issue=Issue{id=1309634546845442540, tenantId=1146029695717560320, journalId=1227999776411738115, year='2026', volume='36', issue='5', pageStart='321', pageEnd='400', issueExtLink='null', onlineDate='null', pubDate='1779638400000', pubDateStr='2026-05-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1790170807800, creator='13701087609', updateTime=1790218979984, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1309836595717570703, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634546845442540, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1309836595717570704, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634546845442540, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=329, endPage=332, ext={EN=ArticleExt(id=1309634547482976750, articleId=1309634547323593198, tenantId=1146029695717560320, journalId=1227999776411738115, language=EN, title=Preliminary Evaluation of the Analgesic and Anti-Inflammatory Effects of Gout Pills, columnId=null, journalTitle=Pharmacy Today, columnName=null, runingTitle=null, highlight=null, articleAbstract=
OBJECTIVE

To evaluate the analgesic and anti-inflammatory effects of gout pills using animal experiments.

METHODS

The mice were randomly divided into low-medium and high-dose gout pill groups, the model control group and positive control group. The analgesic and anti-inflammatory effects of gout pills were initially evaluated through the acetic acid-induced writhing test, ear swelling test, capillary permeability test and measurement of certain inflammatory factors.

RESULTS

Gout pills significantly reduce the number of writhes, auricular swelling degree and capillary permeability, serum levels of IL-6 and TH1 levels in mice, and elevated the levels of TH2 and IgG.

CONCLUSION

Gout pills have good anti-inflammatory and analgesic effects.

, authors=Yiyun WANG1, Yibo LIANG1, Wei SHEN1, Yuanyi ZHOU1, Zongming LUO2, Dong LV1, *, authorsList=Yiyun WANG, Yibo LIANG, Wei SHEN, Yuanyi ZHOU, Zongming LUO, Dong LV, authorCompany=null, correspAuthors=Dong LV, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1309634547759800816, articleId=1309634547323593198, tenantId=1146029695717560320, journalId=1227999776411738115, language=CN, title=痛风丸镇痛、抗炎作用的初步评价, columnId=1228268589086606089, journalTitle=今日药学, columnName=论著, runingTitle=null, highlight=null, articleAbstract=
目的

利用动物实验评价痛风丸的镇痛、抗炎作用。

方法

将小鼠随机分为痛风丸低、中、高剂量组、模型对照组及阳性对照组,通过小鼠醋酸扭体实验、耳肿胀实验、毛细血管通透性实验及部分炎性因子的测量,初步评价痛风丸的镇痛、抗炎作用。

结果

痛风丸可显著降低小鼠扭体次数、耳廓肿胀度、毛细血管通透性、小鼠血清IL-6、TH1水平,升高TH2、IgG水平。

结论

痛风丸具有良好的抗炎、镇痛作用。

, authors=王奕匀1, 梁一博1, 沈薇1, 周圆一1, 罗宗明2, 吕栋1, *, authorsList=王奕匀, 梁一博, 沈薇, 周圆一, 罗宗明, 吕栋, authorCompany=null, correspAuthors=吕栋, authorNote=

王奕匀,主管药师,研究方向:药品、化妆品、生物制品的安全性评价

, correspAuthorsNote=

*

吕栋,副主任药师,研究方向:药品、化妆品安全性评价,E-mail:
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痛风丸镇痛、抗炎作用的初步评价
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王奕匀 1 , 梁一博 1 , 沈薇 1 , 周圆一 1 , 罗宗明 2 , 吕栋 1, *
今日药学 | 论著 2026,36(5): 329-332
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今日药学 |论著 2026 , 36 (5) : 329 -332
痛风丸镇痛、抗炎作用的初步评价
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王奕匀1, 梁一博1, 沈薇1, 周圆一1, 罗宗明2, 吕栋1, *
作者信息
  • 1.甘肃省药品检验研究院,甘肃 兰州 730070
  • 2.甘肃鸿恩民间中草药医研究所,甘肃 兰州 730030
通讯作者:

*

吕栋,副主任药师,研究方向:药品、化妆品安全性评价,E-mail:
作者简介:

王奕匀,主管药师,研究方向:药品、化妆品、生物制品的安全性评价

Preliminary Evaluation of the Analgesic and Anti-Inflammatory Effects of Gout Pills
Yiyun WANG1, Yibo LIANG1, Wei SHEN1, Yuanyi ZHOU1, Zongming LUO2, Dong LV1, *
Affiliations
  • 1.Gansu Institute of Drug Control, Lanzhou, Gansu 730070, China
  • 2.Gansu Hong'en Folk Chinese Herbal Medicine Research Institute, Lanzhou, Gansu 730030, China
出版时间: 2026-05-25 doi: 10.12048/j.issn.1674-229X.2026.05.002
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目的

利用动物实验评价痛风丸的镇痛、抗炎作用。

方法

将小鼠随机分为痛风丸低、中、高剂量组、模型对照组及阳性对照组,通过小鼠醋酸扭体实验、耳肿胀实验、毛细血管通透性实验及部分炎性因子的测量,初步评价痛风丸的镇痛、抗炎作用。

结果

痛风丸可显著降低小鼠扭体次数、耳廓肿胀度、毛细血管通透性、小鼠血清IL-6、TH1水平,升高TH2、IgG水平。

结论

痛风丸具有良好的抗炎、镇痛作用。

痛风丸  /  镇痛  /  抗炎  /  IL-6  /  TH1  /  TH2  /  IgG
OBJECTIVE

To evaluate the analgesic and anti-inflammatory effects of gout pills using animal experiments.

METHODS

The mice were randomly divided into low-medium and high-dose gout pill groups, the model control group and positive control group. The analgesic and anti-inflammatory effects of gout pills were initially evaluated through the acetic acid-induced writhing test, ear swelling test, capillary permeability test and measurement of certain inflammatory factors.

RESULTS

Gout pills significantly reduce the number of writhes, auricular swelling degree and capillary permeability, serum levels of IL-6 and TH1 levels in mice, and elevated the levels of TH2 and IgG.

CONCLUSION

Gout pills have good anti-inflammatory and analgesic effects.

Gout Pill  /  analgesic effect  /  anti-inflammatory effect  /  IL-6  /  TH1  /  TH2  /  IgG
王奕匀, 梁一博, 沈薇, 周圆一, 罗宗明, 吕栋. 痛风丸镇痛、抗炎作用的初步评价. 今日药学, 2026 , 36 (5) : 329 -332 . DOI: 10.12048/j.issn.1674-229X.2026.05.002
Yiyun WANG, Yibo LIANG, Wei SHEN, Yuanyi ZHOU, Zongming LUO, Dong LV. Preliminary Evaluation of the Analgesic and Anti-Inflammatory Effects of Gout Pills[J]. Pharmacy Today, 2026 , 36 (5) : 329 -332 . DOI: 10.12048/j.issn.1674-229X.2026.05.002
  • 甘肃省药品科研项目(2023GSMPA063)
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doi: 10.12048/j.issn.1674-229X.2026.05.002
  • 接收时间:2025-08-18
  • 首发时间:2026-09-23
  • 出版时间:2026-05-25
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  • 收稿日期:2025-08-18
基金
甘肃省药品科研项目(2023GSMPA063)
作者信息
    1.甘肃省药品检验研究院,甘肃 兰州 730070
    2.甘肃鸿恩民间中草药医研究所,甘肃 兰州 730030

通讯作者:

*

吕栋,副主任药师,研究方向:药品、化妆品安全性评价,E-mail:
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https://castjournals.cast.org.cn/joweb/jryx/CN/10.12048/j.issn.1674-229X.2026.05.002
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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