Article(id=1309634767075762711, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, articleNumber=null, orderNo=null, doi=10.12048/j.issn.1674-229X.2026.01.004, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1740326400000, receivedDateStr=2025-02-24, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1790170860308, onlineDateStr=2026-09-23, pubDate=1769270400000, pubDateStr=2026-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1790170860308, onlineIssueDateStr=2026-09-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1790170860308, creator=13701087609, updateTime=1790170860308, updator=13701087609, issue=Issue{id=1309634747681304819, tenantId=1146029695717560320, journalId=1227999776411738115, year='2026', volume='36', issue='1', pageStart='1', pageEnd='80', issueExtLink='null', onlineDate='null', pubDate='1769270400000', pubDateStr='2026-01-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1790170855683, creator='13701087609', updateTime=1790219109143, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1309837137445482891, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1309837137445482892, tenantId=1146029695717560320, journalId=1227999776411738115, issueId=1309634747681304819, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=16, endPage=18, ext={EN=ArticleExt(id=1309634767298060824, articleId=1309634767075762711, tenantId=1146029695717560320, journalId=1227999776411738115, language=EN, title=Calculating Freezing Point of NaCl-NH4Cl-H2O Ternary System by SEHM Model, columnId=null, journalTitle=Pharmacy Today, columnName=null, runingTitle=null, highlight=null, articleAbstract=
OBJECTIVE

To predict the freezing point of the NaCl-NH4Cl-H2O ternary system using the semi-empirical hydration model (SEHM).

METHODS

The freezing point of the ternary system was computed from the solution concentration based on the SEHM model, and compared with values obtained from air humidity cryoscopy and cooling curve cryoscopy (FPD-4A cryoscope).

RESULTS

The freezing points calculated by the SEHM model showed good agreement with those measured by air humidity cryoscopy and cooling curve cryoscopy. However, the cooling curve method was limited to dilute solutions due to the limited measurement range of the instrument.

CONCLUSION

The SEHM model provides a reliable approach for calculating the freezing point of the NaCl-NH4Cl-H2O ternary system based on solution concentration.

, authors=Xiaoxiao WEI1, Xiancheng ZHAN2, *, authorsList=Xiaoxiao WEI, Xiancheng ZHAN, authorCompany=null, correspAuthors=Xiancheng ZHAN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1309634767809765914, articleId=1309634767075762711, tenantId=1146029695717560320, journalId=1227999776411738115, language=CN, title=采用半经验水化模型(SEHM)计算NaCl-NH4Cl-H2O三元体系溶液的冰点, columnId=1228268589086606089, journalTitle=今日药学, columnName=论著, runingTitle=null, highlight=null, articleAbstract=
目的

运用半经验水化模型(SEHM)预测NaCl-NH4Cl-H2O三元体系的冰点。

方法

以NaCl-NH4Cl-H2O三元体系为研究体系,基于SEHM模型从溶液浓度推算其冰点,并将计算结果与空气湿度冰点法、步冷曲线法(FPD-4A冰点仪)的测定值进行对比。

结果

SEHM模型计算得到的冰点值与空气湿度冰点法及步冷曲线法的测量结果基本吻合;但步冷曲线法受限于仪器测量范围,仅适用于低浓度溶液。

结论

采用SEHM模型可通过溶液浓度有效计算NaCl-NH4Cl-H2O三元体系的冰点。

, authors=魏箫箫1, 詹先成2, *, authorsList=魏箫箫, 詹先成, authorCompany=null, correspAuthors=詹先成, authorNote=

魏箫箫,主管药师,研究方向:药物稳定性研究

, correspAuthorsNote=

*

詹先成,教授,研究方向:药物稳定性研究,E-mail:
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魏箫箫,主管药师,研究方向:药物稳定性研究

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采用半经验水化模型(SEHM)计算NaCl-NH4Cl-H2O三元体系溶液的冰点
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魏箫箫 1 , 詹先成 2, *
今日药学 | 论著 2026,36(1): 16-18
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今日药学 |论著 2026 , 36 (1) : 16 -18
采用半经验水化模型(SEHM)计算NaCl-NH4Cl-H2O三元体系溶液的冰点
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魏箫箫,主管药师,研究方向:药物稳定性研究

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魏箫箫1, 詹先成2, *
作者信息
  • 1.山东特殊教育职业学院,山东 济南 250000
  • 2.四川大学华西药学院,靶向药物与释药系统教育部重点实验室,四川 成都 610041
通讯作者:

*

詹先成,教授,研究方向:药物稳定性研究,E-mail:
作者简介:

魏箫箫,主管药师,研究方向:药物稳定性研究

Calculating Freezing Point of NaCl-NH4Cl-H2O Ternary System by SEHM Model
Xiaoxiao WEI1, Xiancheng ZHAN2, *
Affiliations
  • 1.Shandong Vocational College of Special Education, Jinan, Shandong 250000, China
  • 2.Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan 610041, China
出版时间: 2026-01-25 doi: 10.12048/j.issn.1674-229X.2026.01.004
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目的

运用半经验水化模型(SEHM)预测NaCl-NH4Cl-H2O三元体系的冰点。

方法

以NaCl-NH4Cl-H2O三元体系为研究体系,基于SEHM模型从溶液浓度推算其冰点,并将计算结果与空气湿度冰点法、步冷曲线法(FPD-4A冰点仪)的测定值进行对比。

结果

SEHM模型计算得到的冰点值与空气湿度冰点法及步冷曲线法的测量结果基本吻合;但步冷曲线法受限于仪器测量范围,仅适用于低浓度溶液。

结论

采用SEHM模型可通过溶液浓度有效计算NaCl-NH4Cl-H2O三元体系的冰点。

NaCl-NH4Cl-H2O三元体系  /  冰点  /  SEHM模型  /  空气湿度冰点法
OBJECTIVE

To predict the freezing point of the NaCl-NH4Cl-H2O ternary system using the semi-empirical hydration model (SEHM).

METHODS

The freezing point of the ternary system was computed from the solution concentration based on the SEHM model, and compared with values obtained from air humidity cryoscopy and cooling curve cryoscopy (FPD-4A cryoscope).

RESULTS

The freezing points calculated by the SEHM model showed good agreement with those measured by air humidity cryoscopy and cooling curve cryoscopy. However, the cooling curve method was limited to dilute solutions due to the limited measurement range of the instrument.

CONCLUSION

The SEHM model provides a reliable approach for calculating the freezing point of the NaCl-NH4Cl-H2O ternary system based on solution concentration.

NaCl-NH4Cl-H2O ternary system  /  freezing point  /  SEHM model  /  air humidity cryoscopy  /  cooling curve cryoscopy
魏箫箫, 詹先成. 采用半经验水化模型(SEHM)计算NaCl-NH4Cl-H2O三元体系溶液的冰点. 今日药学, 2026 , 36 (1) : 16 -18 . DOI: 10.12048/j.issn.1674-229X.2026.01.004
Xiaoxiao WEI, Xiancheng ZHAN. Calculating Freezing Point of NaCl-NH4Cl-H2O Ternary System by SEHM Model[J]. Pharmacy Today, 2026 , 36 (1) : 16 -18 . DOI: 10.12048/j.issn.1674-229X.2026.01.004
  • 国家自然科学基金资助项目(81273444)
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doi: 10.12048/j.issn.1674-229X.2026.01.004
  • 接收时间:2025-02-24
  • 首发时间:2026-09-23
  • 出版时间:2026-01-25
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  • 收稿日期:2025-02-24
基金
国家自然科学基金资助项目(81273444)
作者信息
    1.山东特殊教育职业学院,山东 济南 250000
    2.四川大学华西药学院,靶向药物与释药系统教育部重点实验室,四川 成都 610041

通讯作者:

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詹先成,教授,研究方向:药物稳定性研究,E-mail:
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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