Article(id=1292765538418192612, tenantId=1146029695717560320, journalId=1291416979304972313, issueId=1291824268032110598, articleNumber=null, orderNo=null, doi=10.3969/j.issn.1005-4847.2026.03.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1744819200000, receivedDateStr=2025-04-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1786148922781, onlineDateStr=2026-08-08, pubDate=1774800000000, pubDateStr=2026-03-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1786148922781, onlineIssueDateStr=2026-08-08, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1786148922781, creator=13701087609, updateTime=1786148922781, updator=13701087609, issue=Issue{id=1291824268032110598, tenantId=1146029695717560320, journalId=1291416979304972313, year='2026', volume='34', issue='3', pageStart='313', pageEnd='468', issueExtLink='null', onlineDate='null', pubDate='1774800000000', pubDateStr='2026-03-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1785924506432, creator='ztmeta', updateTime=1786331936953, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1293533155567366441, tenantId=1146029695717560320, journalId=1291416979304972313, issueId=1291824268032110598, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1293533155567366442, tenantId=1146029695717560320, journalId=1291416979304972313, issueId=1291824268032110598, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=459, endPage=468, ext={EN=ArticleExt(id=1292765538564993253, articleId=1292765538418192612, tenantId=1146029695717560320, journalId=1291416979304972313, language=EN, title=Evaluation of skeletal muscle injury animal models based on characteristics of Chinese and western medicine clinical syndromes, columnId=null, journalTitle=Acta Laboratorium Animalis Scientia Sinica, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Skeletal muscle injury (SMI) is relatively common in clinical practice, and there are different understandings and approaches to its pathogenesis and treatment strategies between Chinese and western medicine. The development of animal models of SMI that can reflect the clinical characteristics of Chinese and western medicine is of great significance to the in-depth study of its pathogenesis and the exploration of effective treatment method. In this paper, starting from the Chinese and western medical etiology and pathogenesis, diagnostic criteria, and identification and typing of SMI, we conducted a comprehensive evaluation of the construction method and characteristics of the existing animal models and their compatibility with Chinese and western medical conditions. The result showed that the heavy falling blow model had the highest degree of agreement with Chinese and western medical conditions, with 69.6% of Chinese and Western medical agreement and 49.4% of Chinese medical agreement; followed by the exercise-induced model, with 49.8% of western medical agreement and 44.1% of Chinese medical agreement; and chemical stimulation and ischemia/reperfusion models had the lowest degree of agreement. Overall, the animal models of SMI involved in this paper were better than the Chinese medical model in terms of western medical agreement, and the existing models were difficult to correspond accurately with the Chinese medical diagnosis and typing. Therefore, the construction of animal models that can accurately reflect the characteristics of Chinese and western medicine and Chinese medicine patterns is still an important direction for future research.

, authors=Yingjun WEI¹, Xingwen XIE^{1, 2, *}, Dingpeng LI^{1, 3}, Xuan HOU⁴, authorsList=Yingjun WEI, Xingwen XIE, Dingpeng LI, Xuan HOU, authorCompany=null, correspAuthors=Xingwen XIE, authorNote=null, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1292765538791485670, articleId=1292765538418192612, tenantId=1146029695717560320, journalId=1291416979304972313, language=CN, title=基于中西医临床病证特点的骨骼肌损伤动物模型评价, columnId=1292765517996122928, journalTitle=中国实验动物学报, columnName=研究进展, runingTitle=null, highlight=null, articleAbstract=

骨骼肌损伤(skeletal muscle injury, SMI)在临床实践中较为常见，中西医对其病理机制和治疗策略存在不同的理解和方法。开发能够体现中西医临床特征的SMI动物模型，对于深入研究其发病机制和探索有效的治疗方法具有重要意义。本文从SMI的中西医病因病机、诊断标准、辨证分型出发，对现有动物模型的构建方法、特点及其与中西医病症的吻合度进行了综合评价。结果显示，重物坠落打击模型与中西医病症的吻合度最高，其中西医吻合度为69.6%，中医吻合度为49.4%；其次是运动诱导模型，西医吻合度为49.8%，中医吻合度为44.1%；而化学刺激和缺血再灌注模型的吻合度最低。总体而言，本文涉及的SMI动物模型在西医吻合度上优于中医吻合度，且现有模型难以与中医辨证分型精准对应。因此，构建能够准确反映中西医病证特点及中医证型的动物模型仍是未来研究的重要方向。

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魏英俊，男，在读博士研究生，研究方向：中医骨伤科学。Email：2206461194@qq.com

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魏英俊，男，在读博士研究生，研究方向：中医骨伤科学。Email：2206461194@qq.com

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