Article(id=1244321221098188993, tenantId=1146029695717560320, journalId=1244284848500682798, issueId=1244321215637209904, articleNumber=null, orderNo=null, doi=10.16156/j.1004-7220.2025.05.002, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1759248000000, receivedDateStr=2025-10-01, revisedDate=1760025600000, revisedDateStr=2025-10-10, acceptedDate=null, acceptedDateStr=null, onlineDate=1774598897479, onlineDateStr=2026-03-27, pubDate=1759248000000, pubDateStr=2025-10-01, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1774598897479, onlineIssueDateStr=2026-03-27, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774598897479, creator=13701087609, updateTime=1774598897479, updator=13701087609, issue=Issue{id=1244321215637209904, tenantId=1146029695717560320, journalId=1244284848500682798, year='2025', volume='40', issue='5', pageStart='1079', pageEnd='1366', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1774598896178, creator=13701087609, updateTime=1774599509568, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1244323788452639476, tenantId=1146029695717560320, journalId=1244284848500682798, issueId=1244321215637209904, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1244323788452639477, tenantId=1146029695717560320, journalId=1244284848500682798, issueId=1244321215637209904, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1092, endPage=1100, ext={EN=ArticleExt(id=1244321221458899141, articleId=1244321221098188993, tenantId=1146029695717560320, journalId=1244284848500682798, language=EN, title=Biomechanical Mechanism and Clinical Research Progress of Knee Osteotomy, columnId=1244321221362430147, journalTitle=Journal of Medical Biomechanics, columnName=Expert Forum, runingTitle=null, highlight=null, articleAbstract=

Knee osteoarthritis (OA) is a primary cause of joint dysfunction. Knee osteotomy has garnered significant attention due to its potential to delay the progression of knee OA and enhance joint function. As a pivotal biomechanical factor in the onset and progression of OA, the accurate correction of abnormal knee alignment is the central objective of knee osteotomy. This article systematically reviews the biomechanical research progress related to knee osteotomy, with a focus on the precision and personalized correction of force line. The development of new classification system and measurement technology of force line is summarized, the biomechanical mechanism of knee OA induced by abnormal mechanical load is analyzed, and the goal of force line and clinical application progress of knee osteotomy is discusses, so as to provide a new perspective and idea for the clinical treatment of knee OA with knee osteotomy.

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膝骨关节炎（osteoarthritis，OA）是导致关节功能障碍的主要原因之一。膝关节周围截骨因能延缓膝OA进展、改善关节功能而备受关注。膝关节力线异常是膝OA发生发展的关键生物力学因素，其精准控制是膝关节周围截骨术的核心目标。本文系统综述了膝关节周围截骨术相关的生物力学研究进展，重点围绕力线的精准化与个性化矫正展开：梳理了力线分型体系与测量技术的发展，分析了异常力学负荷诱发膝OA的生物力学机制，探讨了膝关节周围截骨术的力线目标与临床应用进展，以期为临床膝关节周围截骨治疗膝OA提供新的视角与思路。

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Patient-specific instrumentation for medial opening wedge high tibial osteotomies in the management of medial compartment osteoarthritis yields high accuracy and low complication rates: A systematic review[J]. J ISAKOS, 2023, 8(3): 163-176., articleTitle=Patient-specific instrumentation for medial opening wedge high tibial osteotomies in the management of medial compartment osteoarthritis yields high accuracy and low complication rates: A systematic review, refAbstract=null), Reference(id=1244321244456268247, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, doi=null, pmid=null, pmcid=null, year=2021, volume=26, issue=3, pageStart=339, pageEnd=345, url=null, language=null, rfNumber=[70], rfOrder=69, authorNames=JIANG X, XIE K, LI B, journalName=J Shanghai Jiaotong Univ Sci, refType=null, unstructuredReference=JIANG X, XIE K, LI B, et al. Using a patient-specific 3D-printed surgical guide for high tibial osteotomy: A technical note[J]. 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Orthop Surg, 2023, 15(11): 2786-2793., articleTitle=Micro electromechanical system navigation assists femoral extramedullary alignment osteotomy in total knee arthroplasty: A single-blind randomizing Study, refAbstract=null), Reference(id=1244321244783423968, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, doi=null, pmid=null, pmcid=null, year=2024, volume=6, issue=1, pageStart=39, pageEnd=null, url=null, language=null, rfNumber=[73], rfOrder=72, authorNames=CHUI ECS, MAK KKK, NG RHT, journalName=Arthroplasty, refType=null, unstructuredReference=CHUI ECS, MAK KKK, NG RHT, et al. Application of image recognition-based tracker-less augmented reality navigation system in a series of sawbone trials[J]. Arthroplasty, 2024, 6(1): 39., articleTitle=Application of image recognition-based tracker-less augmented reality navigation system in a series of sawbone trials, refAbstract=null), Reference(id=1244321244879892965, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, doi=null, pmid=null, pmcid=null, year=2024, volume=19, issue=11, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[74], rfOrder=73, authorNames=BAEK JH, LEE SC, LEE DN, journalName=PLoS One, refType=null, unstructuredReference=BAEK JH, LEE SC, LEE DN, et al. Better accuracy of robotic-assisted total knee arthroplasty compared to conventional technique in patients with failed high tibial osteotomy[J]. PLoS One, 2024, 19(11): e0313391., articleTitle=Better accuracy of robotic-assisted total knee arthroplasty compared to conventional technique in patients with failed high tibial osteotomy, refAbstract=null)], funds=[Fund(id=1244321231273570997, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, awardId=12272232; 82202680, language=CN, fundingSource=国家自然科学基金项目(12272232; 82202680), fundOrder=null, country=null), Fund(id=1244321231378428609, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, awardId=22YF1422900, language=CN, fundingSource=上海市科学技术委员会启明星培育项目(22YF1422900), fundOrder=null, country=null), Fund(id=1244321231516840654, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, awardId=JYZZ219, language=CN, fundingSource=上海交通大学医学院附属第九人民医院种子基金(JYZZ219), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1244321222599749854, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, xref=null, ext=[AuthorCompanyExt(id=1244321222616527071, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, companyId=1244321222599749854, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China), AuthorCompanyExt(id=1244321222641692897, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, companyId=1244321222599749854, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=上海交通大学医学院附属第九人民医院　骨科，上海市骨科内植物重点实验室，上海　200011)])], figs=[ArticleFig(id=1244321229973336615, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=EN, label=Fig. 1, caption=Mechanism of subchondral bone remodeling induced by abnormal mechanical environment, figureFileSmall=bSIhjfMNtHYywYdR6lbg4Q==, figureFileBig=ZF3gFGRqv1r5OWOSjFBbOA==, tableContent=null), ArticleFig(id=1244321230073999923, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=CN, label=图1, caption=异常力学环境诱导软骨下骨骨重塑的机制, figureFileSmall=bSIhjfMNtHYywYdR6lbg4Q==, figureFileBig=ZF3gFGRqv1r5OWOSjFBbOA==, tableContent=null), ArticleFig(id=1244321230342435403, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=EN, label=Fig. 2, caption=Mechanism of cartilage injury induced by abnormal mechanical environment, figureFileSmall=Kt8stfftPvSEzQWfUET5VA==, figureFileBig=wxmYt+BdY3tDaSQQHeI/FQ==, tableContent=null), ArticleFig(id=1244321230506013277, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=CN, label=图2, caption=异常力学环境诱导软骨损伤的机制, figureFileSmall=Kt8stfftPvSEzQWfUET5VA==, figureFileBig=wxmYt+BdY3tDaSQQHeI/FQ==, tableContent=null), ArticleFig(id=1244321230686368367, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=EN, label=Tab. 1, caption=

CPAK classification

, figureFileSmall=null, figureFileBig=null, tableContent=

CPAK分型	aHKA/（°）	JLO	特点
Ⅰ型	<-2	<177	内翻aHKA及顶点远端JLO
Ⅱ型	0±2	<177	中立aHKA及顶点远端JLO
Ⅲ型	>2	<177	外翻aHKA及顶点远端JLO
Ⅳ型	<-2	180±3	内翻aHKA及中立JLO
Ⅴ型	0±2	180±3	中立aHKA及中立JLO
Ⅵ型	>2	180±3	外翻aHKA及中立JLO
Ⅶ型	<-2	>183	内翻aHKA及顶点近端JLO
Ⅷ型	0±2	>183	中立aHKA及顶点近端JLO
Ⅸ型	>2	>183	外翻aHKA及顶点近端JLO

), ArticleFig(id=1244321230828974721, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=CN, label=表1, caption=

CPAK分型

, figureFileSmall=null, figureFileBig=null, tableContent=

CPAK分型	aHKA/（°）	JLO	特点
Ⅰ型	<-2	<177	内翻aHKA及顶点远端JLO
Ⅱ型	0±2	<177	中立aHKA及顶点远端JLO
Ⅲ型	>2	<177	外翻aHKA及顶点远端JLO
Ⅳ型	<-2	180±3	内翻aHKA及中立JLO
Ⅴ型	0±2	180±3	中立aHKA及中立JLO
Ⅵ型	>2	180±3	外翻aHKA及中立JLO
Ⅶ型	<-2	>183	内翻aHKA及顶点近端JLO
Ⅷ型	0±2	>183	中立aHKA及顶点近端JLO
Ⅸ型	>2	>183	外翻aHKA及顶点近端JLO

), ArticleFig(id=1244321230946415246, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=EN, label=Tab. 2, caption=

Correction goals for the percentage of WBL in the tibial plateau after HTO

, figureFileSmall=null, figureFileBig=null, tableContent=

内翻畸形及以下情况	WBL百分比的目标位置/%
①内侧负荷过大但无相应的软骨损伤	50~55
②没有骨关节炎的手术操作
①内侧关节腔骨关节炎I级或II级	55~60
②进行软骨重建术（OATS，ACT）
③半月板修复/移植
④慢性外侧/后外侧不稳定
①内侧关节腔骨关节炎III级或IV级	60~65

), ArticleFig(id=1244321231084827294, tenantId=1146029695717560320, journalId=1244284848500682798, articleId=1244321221098188993, language=CN, label=表2, caption=

HTO术后胫骨平台WBL百分比的矫正目标

, figureFileSmall=null, figureFileBig=null, tableContent=

内翻畸形及以下情况	WBL百分比的目标位置/%
①内侧负荷过大但无相应的软骨损伤	50~55
②没有骨关节炎的手术操作
①内侧关节腔骨关节炎I级或II级	55~60
②进行软骨重建术（OATS，ACT）
③半月板修复/移植
④慢性外侧/后外侧不稳定
①内侧关节腔骨关节炎III级或IV级	60~65

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