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Addressing the persistent challenge that general safety regulations are inadequate for metal mines employing specialized processes such as in-situ leaching, this study focuses on China's dominant in-situ leaching uranium mines and proposes a safety governance framework termed "three-layer decoupling and bidirectional integration". This methodology systematically develops China's Safety Regulations for In-situ Leaching Uranium Mines and three sets of mandatory safety assessment templates by decoupling complex risks, process stages, and heterogeneous standards, and integrating on-site requirements with regulatory provisions. The innovations are reflected in: the first cross-industry transformation and process adaptation of safety standards from multiple fields such as geological exploration and chemical engineering pipelines; the use of numerical simulation technology to verify and optimize threshold values for key clauses concerning drilling stability and leakage diffusion; and the complete reconstruction of the safety assessment paradigm, establishing a "standard-evaluation" closed-loop management and control system deeply integrated with the regulations. The outcomes have been implemented as mandatory industry standards. Application data indicate that mine safety compliance inspection efficiency has improved by approximately 50%. The systematic construction method and the integrated "regulation-assessment-application" formed in this research provide a replicable solution for the safety governance of other metal mines using similar leaching processes.

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采用原地浸出工艺开采金属矿山，长期面临通用安全法规“不适用、不管用”的行业共性难题。以中国主导产能的原地浸出铀矿为研究对象，提出并实践了“三层解耦-双向融合”的安全治理体系构建方法论。该方法通过解耦复杂风险、工艺环节与异源标准，并融合现场需求与法规条款，制定了中国首部《原地浸出铀矿山安全规程》及其相应的强制性安全评价模板。该研究首次实现了地质勘探、化工管道等多领域安全标准的跨行业转化与工艺适配；采用数值仿真技术对钻井稳定性、泄漏扩散等关键条款的阈值进行了验证与优化；重构了安全评价范式，建立了与《规程》深度绑定的“标准-评价”闭环管控体系。研究成果已作为行业强制标准实施，实际应用显示矿山安全合规检查效率提升约50%。本研究所形成的体系化构建方法及“规-评-用”一体化成果，为稀土、铜等同类溶浸工艺金属矿山的安全治理，提供了具备高度可复制性的系统解决方案。

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