Article(id=1322943461141389643, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322942780003201932, articleNumber=null, orderNo=null, doi=10.14062/j.issn.0454-5648.20210204, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1616774400000, receivedDateStr=2021-03-27, revisedDate=1618761600000, revisedDateStr=2021-04-19, acceptedDate=null, acceptedDateStr=null, onlineDate=1793343900236, onlineDateStr=2026-10-30, pubDate=1632067200000, pubDateStr=2021-09-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793343900236, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793343900236, creator=13701087609, updateTime=1793343900236, updator=13701087609, issue=Issue{id=1322942780003201932, tenantId=1146029695717560320, journalId=1263187385517883426, year='2021', volume='49', issue='9', pageStart='1785', pageEnd='2044', issueExtLink='null', onlineDate='null', pubDate='1632067200000', pubDateStr='2021-09-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793343737841, creator='13701087609', updateTime=1793345873558, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322951737916665918, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322942780003201932, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322951737916665919, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322942780003201932, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1837, endPage=1845, ext={EN=ArticleExt(id=1322943461544042828, articleId=1322943461141389643, tenantId=1146029695717560320, journalId=1263187385517883426, language=EN, title=Mechanical and Biological Properties of ZrO2 Bioceramics by Stereolithography Technique, columnId=1322942810562900072, journalTitle=Journal of the Chinese Ceramic Society, columnName=Additive Manufacturing of Ceramics—Research Article, runingTitle=null, highlight=null, articleAbstract=

In order to use ZrO2 all-ceramic restorations in the dental field, ZrO2 slurry suitable for SL technology was obtained and ZrO2 bioceramic was prepared by SL. The mechanical properties and biocompatibility were investigated. The transformation from m-ZrO2 to t-ZrO2 or c-ZrO2 in the original ZrO2 powder was completed when sintered at different temperatures. The density of ceramic increases and the number of pores decreases as the sintering temperature increases, and the grain size increases and becomes uneven when the temperature further increases. The Vickers hardness and fracture toughness of ZrO2 bioceramic firstly increase and then decrease when the sintering temperature increases from 1 450℃ to 1 600℃, and they reach their maximum values (i.e., 14.87 GPa and 6.73 MPa·m1/2) at 1 500℃. The linear shrinkage and relative density are 23.42% and 97.32%, respectively. In addition, rat bone marrow mesenchymal stem cells (rBMSCs) were used for in vitro cell experiments, thus proving that ZrO2 bioceramic fabricated by SL technique have a good biocompatibility, which can have some application prospects in dental restoration.

, authors=Fen CHEN1, 2, Yaru WU1, 2, Hao ZHU3, Jiamin WU1, 2, Jun XIAO3, Yusheng SHI1, 2, authorsList=Fen CHEN, Yaru WU, Hao ZHU, Jiamin WU, Jun XIAO, Yusheng SHI, authorCompany=null, correspAuthors=Jiamin WU, authorNote=

CHEN Fen (1997-), female, Master candidate. E-mail:

, correspAuthorsNote=
WU Jiamin (1984-), male, Ph.D., Associate Professor. E-mail:
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制备了用于立体光固化技术(SL)的ZrO2浆料,采用SL打印制备了ZrO2生物陶瓷,研究了烧结样品的力学性能与生物相容性。经过不同温度烧结后,ZrO2原粉中的m-ZrO2均完成了向t-ZrO2或c-ZrO2的转变。随着烧结温度的提高,陶瓷致密化程度提高,气孔数量减少;当烧结温度继续提高时,晶粒尺寸继续增大且大小不均匀。当烧结温度从1 450℃升高至1 600℃时,ZrO2生物陶瓷的维氏硬度和断裂韧性先增大后减小,且均在1 500℃达到最大值,分别为14.87 GPa和6.73 MPa·m1/2,此时的线收缩率与相对密度分别为23.42%和97.32%。同时利用大鼠骨髓间充质干细胞(rBMSCs)进行体外细胞实验,证明了SL成形的ZrO2生物陶瓷具有较好的生物相容性,在牙科修复中具有广阔的应用前景。

, authors=陈芬1, 2, 吴亚茹1, 2, 朱皓3, 吴甲民1, 2, 肖骏3, 史玉升1, 2, authorsList=陈芬, 吴亚茹, 朱皓, 吴甲民, 肖骏, 史玉升, authorCompany=null, correspAuthors=吴甲民, authorNote=

陈芬(1997—),女,硕士研究生。

, correspAuthorsNote=
吴甲民(1984—),男,副教授。
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氧化锆生物陶瓷的立体光固化制备及其力学与生物性能
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陈芬 1, 2 , 吴亚茹 1, 2 , 朱皓 3 , 吴甲民 1, 2 , 肖骏 3 , 史玉升 1, 2
硅酸盐学报 | 陶瓷增材制造专题-研究论文 2021,49(9): 1837-1845
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硅酸盐学报 |陶瓷增材制造专题-研究论文 2021 , 49 (9) : 1837 -1845
氧化锆生物陶瓷的立体光固化制备及其力学与生物性能
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陈芬1, 2 , 吴亚茹1, 2, 朱皓3, 吴甲民1, 2 , 肖骏3, 史玉升1, 2
作者信息
  • 1.华中科技大学材料科学与工程学院,材料成形与模具技术国家重点实验室,武汉 430074
  • 2.增材制造陶瓷材料教育部工程研究中心,武汉 430074
  • 3.华中科技大学同济医学院同济医院骨科,武汉 430030
通讯作者:
吴甲民(1984—),男,副教授。
作者简介:

陈芬(1997—),女,硕士研究生。

Mechanical and Biological Properties of ZrO2 Bioceramics by Stereolithography Technique
Fen CHEN1, 2 , Yaru WU1, 2, Hao ZHU3, Jiamin WU1, 2 , Jun XIAO3, Yusheng SHI1, 2
Affiliations
  • 1.State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
  • 2.Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China
  • 3.Department of Orthopedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China
  • Corresponding Author:
    WU Jiamin (1984-), male, Ph.D., Associate Professor. E-mail:

    CHEN Fen (1997-), female, Master candidate. E-mail:

出版时间: 2021-09-20 doi: 10.14062/j.issn.0454-5648.20210204
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制备了用于立体光固化技术(SL)的ZrO2浆料,采用SL打印制备了ZrO2生物陶瓷,研究了烧结样品的力学性能与生物相容性。经过不同温度烧结后,ZrO2原粉中的m-ZrO2均完成了向t-ZrO2或c-ZrO2的转变。随着烧结温度的提高,陶瓷致密化程度提高,气孔数量减少;当烧结温度继续提高时,晶粒尺寸继续增大且大小不均匀。当烧结温度从1 450℃升高至1 600℃时,ZrO2生物陶瓷的维氏硬度和断裂韧性先增大后减小,且均在1 500℃达到最大值,分别为14.87 GPa和6.73 MPa·m1/2,此时的线收缩率与相对密度分别为23.42%和97.32%。同时利用大鼠骨髓间充质干细胞(rBMSCs)进行体外细胞实验,证明了SL成形的ZrO2生物陶瓷具有较好的生物相容性,在牙科修复中具有广阔的应用前景。

增材制造  /  氧化锆  /  立体光固化  /  力学性能  /  生物相容性

In order to use ZrO2 all-ceramic restorations in the dental field, ZrO2 slurry suitable for SL technology was obtained and ZrO2 bioceramic was prepared by SL. The mechanical properties and biocompatibility were investigated. The transformation from m-ZrO2 to t-ZrO2 or c-ZrO2 in the original ZrO2 powder was completed when sintered at different temperatures. The density of ceramic increases and the number of pores decreases as the sintering temperature increases, and the grain size increases and becomes uneven when the temperature further increases. The Vickers hardness and fracture toughness of ZrO2 bioceramic firstly increase and then decrease when the sintering temperature increases from 1 450℃ to 1 600℃, and they reach their maximum values (i.e., 14.87 GPa and 6.73 MPa·m1/2) at 1 500℃. The linear shrinkage and relative density are 23.42% and 97.32%, respectively. In addition, rat bone marrow mesenchymal stem cells (rBMSCs) were used for in vitro cell experiments, thus proving that ZrO2 bioceramic fabricated by SL technique have a good biocompatibility, which can have some application prospects in dental restoration.

additive manufacturing  /  zirconia  /  stereolithography  /  mechanical properties  /  biocompatibility
陈芬, 吴亚茹, 朱皓, 吴甲民, 肖骏, 史玉升. 氧化锆生物陶瓷的立体光固化制备及其力学与生物性能. 硅酸盐学报, 2021 , 49 (9) : 1837 -1845 . DOI: 10.14062/j.issn.0454-5648.20210204
Fen CHEN, Yaru WU, Hao ZHU, Jiamin WU, Jun XIAO, Yusheng SHI. Mechanical and Biological Properties of ZrO2 Bioceramics by Stereolithography Technique[J]. Journal of the Chinese Ceramic Society, 2021 , 49 (9) : 1837 -1845 . DOI: 10.14062/j.issn.0454-5648.20210204
  • 国家重点研发计划(2018YFB1105503)
  • 湖北省技术创新专项重大项目(2019AAA002)
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2021年第49卷第9期
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doi: 10.14062/j.issn.0454-5648.20210204
  • 接收时间:2021-03-27
  • 首发时间:2026-10-30
  • 出版时间:2021-09-20
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  • 收稿日期:2021-03-27
  • 修回日期:2021-04-19
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国家重点研发计划(2018YFB1105503)
湖北省技术创新专项重大项目(2019AAA002)
作者信息
    1.华中科技大学材料科学与工程学院,材料成形与模具技术国家重点实验室,武汉 430074
    2.增材制造陶瓷材料教育部工程研究中心,武汉 430074
    3.华中科技大学同济医学院同济医院骨科,武汉 430030

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吴甲民(1984—),男,副教授。
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https://castjournals.cast.org.cn/joweb/gsyxb/CN/10.14062/j.issn.0454-5648.20210204
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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