Article(id=1322917095939387413, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322917095268295267, articleNumber=null, orderNo=null, doi=10.14062/j.issn.0454-5648.20200346, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1589731200000, receivedDateStr=2020-05-18, revisedDate=1592928000000, revisedDateStr=2020-06-24, acceptedDate=null, acceptedDateStr=null, onlineDate=1793337614283, onlineDateStr=2026-10-30, pubDate=1608393600000, pubDateStr=2020-12-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793337614283, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793337614282, creator=13701087609, updateTime=1793337614282, updator=13701087609, issue=Issue{id=1322917095268295267, tenantId=1146029695717560320, journalId=1263187385517883426, year='2020', volume='48', issue='12', pageStart='1865', pageEnd='2010', issueExtLink='null', onlineDate='null', pubDate='1608393600000', pubDateStr='2020-12-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793337614123, creator='13701087609', updateTime=1793345927101, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322951962475507806, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322917095268295267, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322951962475507807, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1322917095268295267, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1944, endPage=1952, ext={EN=ArticleExt(id=1322917096136519702, articleId=1322917095939387413, tenantId=1146029695717560320, journalId=1263187385517883426, language=EN, title=Research Progress of Monosodium Urate Monohydrate Crystals, columnId=null, journalTitle=Journal of the Chinese Ceramic Society, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Gout is a term given to the disorder of uric acid metabolism, which results from the deposition of crystals of monosodium urate monohydrate in various connective tissues. Recent domestic researches on the treatment of gout still focus on the development and application of medicine, mainly through drug treatment and acupuncture to relieve the pain of patients. However, less attention is paid to the mechanism of monosodium urate monohydrate crystallization. In principle, gout is the crystallization of monosodium urate solute when it reaches supersaturation in the body fluid circulation. This review, from the perspective of materials, represented recent research work on the structure, morphology, in vitro preparation method and inhibition method of monosodium urate monohydrate crystals, and put forward the direction of further research in the future.

, authors=Tian TIAN, Zefen LI, Jiayue XU, authorsList=Tian TIAN, Zefen LI, Jiayue XU, authorCompany=null, correspAuthors=Jiayue XU, authorNote=

TIAN tian (1985-), male, Ph.D., associate Professor. E-mail:

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XU jiayue (1965-), male, Ph.D., Professor. E-mail:
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目前国内对于痛风的治疗研究仍集中在医药领域,主要通过药物治疗和针灸治疗缓解患者的疼痛,对尿酸钠结晶机理研究关注较少。从原理上进行分析,痛风是尿酸钠溶质在体液循环中达到过饱和时的结晶表现。从材料学的角度出发,阐述了尿酸钠晶体的结构、形貌、体外制备方法和抑制手段等方面的研究进展,并提出了未来可进一步开展研究的方向。

, authors=田甜, 李泽芬, 徐家跃, authorsList=田甜, 李泽芬, 徐家跃, authorCompany=null, correspAuthors=徐家跃, authorNote=

田甜(1985—),男,博士,副教授。

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徐家跃(1965—),男,博士,教授。
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尿酸钠晶体的研究进展
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田甜 , 李泽芬 , 徐家跃
硅酸盐学报 | 综合评述 2020,48(12): 1944-1952
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硅酸盐学报 |综合评述 2020 , 48 (12) : 1944 -1952
尿酸钠晶体的研究进展
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田甜 , 李泽芬, 徐家跃
作者信息
  • 上海应用技术大学材料科学与工程学院,晶体生长研究所,上海 201418
通讯作者:
徐家跃(1965—),男,博士,教授。
作者简介:

田甜(1985—),男,博士,副教授。

Research Progress of Monosodium Urate Monohydrate Crystals
Tian TIAN , Zefen LI, Jiayue XU
Affiliations
  • Institute of Crystal Growth, School of Materials Science and Engineering, Shanghai Institute of Technology, Shanghai 201418, China
  • Corresponding Author:
    XU jiayue (1965-), male, Ph.D., Professor. E-mail:

    TIAN tian (1985-), male, Ph.D., associate Professor. E-mail:

出版时间: 2020-12-20 doi: 10.14062/j.issn.0454-5648.20200346
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目前国内对于痛风的治疗研究仍集中在医药领域,主要通过药物治疗和针灸治疗缓解患者的疼痛,对尿酸钠结晶机理研究关注较少。从原理上进行分析,痛风是尿酸钠溶质在体液循环中达到过饱和时的结晶表现。从材料学的角度出发,阐述了尿酸钠晶体的结构、形貌、体外制备方法和抑制手段等方面的研究进展,并提出了未来可进一步开展研究的方向。

痛风  /  尿酸钠晶体  /  晶体生长  /  抑制机理

Gout is a term given to the disorder of uric acid metabolism, which results from the deposition of crystals of monosodium urate monohydrate in various connective tissues. Recent domestic researches on the treatment of gout still focus on the development and application of medicine, mainly through drug treatment and acupuncture to relieve the pain of patients. However, less attention is paid to the mechanism of monosodium urate monohydrate crystallization. In principle, gout is the crystallization of monosodium urate solute when it reaches supersaturation in the body fluid circulation. This review, from the perspective of materials, represented recent research work on the structure, morphology, in vitro preparation method and inhibition method of monosodium urate monohydrate crystals, and put forward the direction of further research in the future.

gout  /  monosodium urate monohydrate crystals  /  crystal growth  /  inhibition mechanism
田甜, 李泽芬, 徐家跃. 尿酸钠晶体的研究进展. 硅酸盐学报, 2020 , 48 (12) : 1944 -1952 . DOI: 10.14062/j.issn.0454-5648.20200346
Tian TIAN, Zefen LI, Jiayue XU. Research Progress of Monosodium Urate Monohydrate Crystals[J]. Journal of the Chinese Ceramic Society, 2020 , 48 (12) : 1944 -1952 . DOI: 10.14062/j.issn.0454-5648.20200346
  • 国家自然科学基金(51972208)
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doi: 10.14062/j.issn.0454-5648.20200346
  • 接收时间:2020-05-18
  • 首发时间:2026-10-30
  • 出版时间:2020-12-20
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  • 收稿日期:2020-05-18
  • 修回日期:2020-06-24
基金
国家自然科学基金(51972208)
作者信息
    上海应用技术大学材料科学与工程学院,晶体生长研究所,上海 201418

通讯作者:

徐家跃(1965—),男,博士,教授。
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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