Article(id=1318978541769839597, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1318978537852359595, articleNumber=null, orderNo=null, doi=10.14062/j.issn.0454-5648.20230189, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1679846400000, receivedDateStr=2023-03-27, revisedDate=1683648000000, revisedDateStr=2023-05-10, acceptedDate=null, acceptedDateStr=null, onlineDate=1792398589794, onlineDateStr=2026-10-19, pubDate=1697731200000, pubDateStr=2023-10-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792398589794, onlineIssueDateStr=2026-10-19, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792398589794, creator=13701087609, updateTime=1792398589794, updator=13701087609, issue=Issue{id=1318978537852359595, tenantId=1146029695717560320, journalId=1263187385517883426, year='2023', volume='51', issue='10', pageStart='2517', pageEnd='2738', issueExtLink='null', onlineDate='null', pubDate='1697731200000', pubDateStr='2023-10-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792398588860, creator='13701087609', updateTime=1792399337892, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1318981679578993157, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1318978537852359595, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1318981679578993158, tenantId=1146029695717560320, journalId=1263187385517883426, issueId=1318978537852359595, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2527, endPage=2535, ext={EN=ArticleExt(id=1318978541996332014, articleId=1318978541769839597, tenantId=1146029695717560320, journalId=1263187385517883426, language=EN, title=Preparation and In Vitro Bioactivity of Cerium-Incorporated Bioglass Microspheres via Spray Drying Method, columnId=1321891267076805371, journalTitle=Journal of the Chinese Ceramic Society, columnName=Special Issue on Inorganic Bioactive Materials—Research Articles, runingTitle=null, highlight=null, articleAbstract=

Bioglass (BG) microspheres with a constitution of CaO-SiO₂-P₂O₅ demonstrate promising applications in bone repair. It has been proved that the cerium ion incorporation in bioglass structure can provide materials with additional antioxidant, anti-inflammatory and angiogenesis functions. In this study, cerium-incorporated bioglass (Ce-BG) microspheres were prepared via a spray drying process. The effects of Ce content on the phase composition, degradation performance and in vitro bioactivity of Ce-BG microspheres were investigated. The results show that all microspheres are uniform in element distribution with relatively smooth surfaces and a high degree of sphericity. The Ce incorporation introduces a small amount of CePO₄ and CeO₂ crystalline phases. Along with the increase of Ce content, the degradation rate of Ce-BG microspheres slows down, and the effect of degradation products on the increase of environmental pH value is alleviated, and the pH value was found to be the lowest after 7 d of immersion for Ce-BG microspheres with mole ratio of Ce and Ce+Ca of 0.03∶1.00 in Tris-HCl buffer. Ce-BG microspheres with different Ce content have good ability to induce apatite deposition in vitro.

, authors=Baolong CHEN¹, Yaping HU¹, Min ZHU¹, Yufang ZHU², authorsList=Baolong CHEN, Yaping HU, Min ZHU, Yufang ZHU, authorCompany=null, correspAuthors=Min ZHU, Yufang ZHU, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1318978542206047215, articleId=1318978541769839597, tenantId=1146029695717560320, journalId=1263187385517883426, language=CN, title=喷雾干燥法制备含铈生物玻璃微球及其体外生物活性, columnId=1321891267257160444, journalTitle=硅酸盐学报, columnName=无机生物活性材料专题—研究论文, runingTitle=null, highlight=null, articleAbstract=

CaO-SiO₂-P₂O₅体系生物玻璃微球在骨修复材料领域具有应用前景。适量铈离子可赋予生物玻璃抗氧化、抗炎、促血管生成等功能特性。通过喷雾干燥法制备了不同铈离子含量的生物玻璃（Ce-BG）微球粉体材料，研究了Ce含量对Ce-BG微球的物相组成、降解性能以及体外生物活性的影响。结果表明：Ce-BG微球表面光滑，球形度高，元素分布均匀；BG微球中添加Ce会生成CePO₄及CeO₂相，且随Ce含量提高，Ce-BG微球降解速率变慢，降解产物引起环境pH值升高逐渐减缓。Ce与Ce+Ca的摩尔比为0.03∶1.00的Ce-BG微球浸泡在Tris-HCl缓冲液中7d后pH值最低。不同Ce含量的Ce-BG微球都具有良好的体外诱导磷灰石沉积的能力。

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CHEN Baolong (1997-), male, Master candidate. E-mail: 1362299424@qq.com

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CHEN Baolong (1997-), male, Master candidate. E-mail: 1362299424@qq.com

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陈宝龙（1997—），男，硕士研究生。

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陈宝龙（1997—），男，硕士研究生。

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